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B8CKS7 (B8CKS7_SHEPW) Unreviewed, UniProtKB/TrEMBL

Last modified May 29, 2013. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphoribosylformylglycinamidine synthase HAMAP-Rule MF_00419
Short name=FGAM synthase HAMAP-Rule MF_00419
Short name=FGAMS HAMAP-Rule MF_00419
EC=6.3.5.3 HAMAP-Rule MF_00419
Alternative name(s):
Formylglycinamide ribotide amidotransferase HAMAP-Rule MF_00419
Formylglycinamide ribotide synthetase HAMAP-Rule MF_00419
Gene names
Name:purL HAMAP-Rule MF_00419
Ordered Locus Names:swp_1467
OrganismShewanella piezotolerans (strain WP3 / JCM 13877) [Complete proteome] [HAMAP] EMBL ACJ28253.1
Taxonomic identifier225849 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Alteromonadales › Shewanellaceae › Shewanella ›

Protein attributes

Sequence length1293 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + H2O = ADP + phosphate + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate. HAMAP-Rule MF_00419 SAAS SAAS022940

Pathway

Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 1/2. HAMAP-Rule MF_00419 SAAS SAAS022940

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00419 SAAS SAAS022940

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00419.

Sequence similarities

Contains 1 glutamine amidotransferase type-1 domain. HAMAP-Rule MF_00419 SAAS SAAS022940

In the N-terminal section; belongs to the FGAMS family. HAMAP-Rule MF_00419

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Domain1040 – 1293254Glutamine amidotransferase type-1 By similarity HAMAP-Rule MF_00419
Nucleotide binding305 – 31612ATP By similarity HAMAP-Rule MF_00419

Sites

Active site11331Nucleophile By similarity HAMAP-Rule MF_00419
Active site12581 By similarity HAMAP-Rule MF_00419
Active site12601 By similarity HAMAP-Rule MF_00419

Sequences

Sequence LengthMass (Da)Tools
B8CKS7 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 43C61359F178E86F

FASTA1,293140,704
        10         20         30         40         50         60 
MEIIRGAPAL SAFRVQKLMQ ACESAALPVR QIYAEFIHLA DLKESLEENE SQQLEKILTY 

        70         80         90        100        110        120 
GPAIEAHQPE GKLHFVTPRP GTISPWSSKA TDIAHNCGLD KVLRLERGIA YYVVADELTA 

       130        140        150        160        170        180 
AQTKSLLELL HDRMVEVVVN DFNAADVLFA RTEPAKFKSV DILGQGRSAL ELANTTLGLA 

       190        200        210        220        230        240 
LAEDEIDYLV ENFKRLERNP NDVELMMFAQ ANSEHCRHKI FNADWTIDGE VQPKSLFKMI 

       250        260        270        280        290        300 
KNTFETTPEN VLSAYKDNAA VMTGSTAGRF FPKQDGVYGY HTEPMHILMK VETHNHPTAI 

       310        320        330        340        350        360 
SPYPGAATGS GGEIRDEGAT GRGSKPKAGL TGFSVSNLKI PGFVQPWEAD YGKPDRIVTA 

       370        380        390        400        410        420 
LDIMTEGPLG GAAFNNEFGR PALVGYFRTY EQEVNSHNGV EVRGYHKPIM LAGGLGNIRE 

       430        440        450        460        470        480 
EHVQKGEITV GAKLVVLGGP AMNIGLGGGA ASSMTSGQSS EDLDFASVQR ENPEMERRCQ 

       490        500        510        520        530        540 
EVIDRCWQMG DANPIQFIHD VGAGGLSNAF PELVDDGGRG GNFELRRVPS DEPGMSPLEI 

       550        560        570        580        590        600 
WCNESQERYV MSIAPENLAV FTAICQRERA PFAVVGVATE ERELILSDEH FENHPIELPL 

       610        620        630        640        650        660 
EVLLGKAPKM SRDVVSAKAN SSALDQSDIA VKEAAHRLLR LPTIAEKTFL ITIGDRTVTG 

       670        680        690        700        710        720 
LVNRDQMVGP WQVPVADCAV TAASYDSYVG EAMSIGERTP LALLDFGASA RMAVAESILN 

       730        740        750        760        770        780 
IAGTDIGSFK RIKLSANWMS PAGHPGEDAG LYEAVKAIGE ELCPDLSLTI PVGKDSMSMK 

       790        800        810        820        830        840 
TAWEDNGVQK AVTSPMSLVI TAFGVVQDVR NTVTPELRSD KGDSELLLLD LGLGQNRLGG 

       850        860        870        880        890        900 
SCLAQVYSEL GDIAPDLDNS ATLKGFFEVI QPLVADQSIL AYHDRSDGGL YTTLVEMAFA 

       910        920        930        940        950        960 
GHTGLNVDLS ALTGTDVERL FNEELGAVIQ VRREDSAAIS AKFNAAGVAC HKVAELTDTD 

       970        980        990       1000       1010       1020 
QIAIFDGERE VLTETRTSLR TIWAETTYRM QSLRDNPECA KEEHALKQDA NDLGLTVDLS 

      1030       1040       1050       1060       1070       1080 
FDPSEDVAAP FILKGAAPKM AILREQGVNS HIEMAAAFDR AGFESKDVHM SDILSGRISL 

      1090       1100       1110       1120       1130       1140 
EEFQGLVACG GFSYGDVLGA GEGWAKSILF NARAREQFSQ FFERDDSFSL GVCNGCQMLS 

      1150       1160       1170       1180       1190       1200 
NLKDIIPGTD LWPHFVRNRS ERFEARFSLV EVQKSPSLFF QGMEGSRMPI AVSHGEGRAE 

      1210       1220       1230       1240       1250       1260 
FASPEALAAA EASGTIALRY VDGNGQIATQ YPQNPNGSPN AITALSSTDG RVTIMMPHPE 

      1270       1280       1290 
RVFRTVANSW HPDSWGEDSP WMRMFRNVRK SIG

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References

[1]"Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3."
Wang F., Wang J., Jian H., Zhang B., Li S., Wang F., Zeng X., Gao L., Bartlett D.H., Yu J., Hu S., Xiao X.
PLoS ONE 3:E1937-E1937(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WP3 / JCM 13877.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000472 Genomic DNA. Translation: ACJ28253.1.

3D structure databases

ProteinModelPortalB8CKS7.
ModBaseSearch...

Protein-protein interaction databases

STRING225849.swp_1467.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACJ28253; ACJ28253; swp_1467.
KEGGswp:swp_1467.
PATRIC23541531. VBIShePie65056_1341.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0046.
HOGENOMHOG000261359.
KOK01952.
OMATVKAVGM.
ProtClustDBPRK05297.

Enzyme and pathway databases

BioCycSPIE225849:GH6V-1415-MONOMER.
UniPathwayUPA00074; UER00128.

Family and domain databases

HAMAPMF_00419. PurL_1.
InterProIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR017926. GATASE.
IPR010073. PRibForGlyAmidine_synth.
IPR022940. PRibForGlyAmidine_synth_bac.
IPR016188. PurM_N-like.
[Graphical view]
PfamPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 2 hits.
[Graphical view]
SUPFAMSSF56042. AIR_synth_C. 2 hits.
SSF55326. PurM_N-like. 2 hits.
TIGRFAMsTIGR01735. FGAM_synt. 1 hit.
PROSITEPS51273. GATASE_TYPE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameB8CKS7_SHEPW
AccessionPrimary (citable) accession number: B8CKS7
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 29, 2013
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info