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B8CI29 (SYR_SHEPW) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 37. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:swp_0474
OrganismShewanella piezotolerans (strain WP3 / JCM 13877) [Complete proteome] [HAMAP]
Taxonomic identifier225849 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaAlteromonadalesShewanellaceaeShewanella

Protein attributes

Sequence length581 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 581581Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_1000198931

Regions

Motif126 – 13611"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
B8CI29 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 4D77FCB4CC518E2D

FASTA58165,067
        10         20         30         40         50         60 
MKSHTQSLLA ESLNALKQQG VVPADFEARI QVDRTKDKSH GDFATNLAMM LTKAARKNPR 

        70         80         90        100        110        120 
EIAQLIIDNL PQSSHVEKVE IAGPGFINFF IDDNALANQL MDALNSDHLG VTLPESQTVV 

       130        140        150        160        170        180 
VDYSSPNLAK EMHVGHLRST IIGDSVVRSL EFMGHNVIRQ NHVGDWGTQF GMLLAYMEEL 

       190        200        210        220        230        240 
RAANGEQAQI ELSDLENFYR AAKVRFDESE DFANRARKLV VALQSGDEYC NKLWREFNDI 

       250        260        270        280        290        300 
SLSHCHEIYE RLGVSLTRQD VRGESSYNDD LEQVVADLDS QGLLSESNGA KVVFQEEFKN 

       310        320        330        340        350        360 
KEGEPLPVII QKADGGYLYA TSDMAAMRYR SNVLKADRAL YFVDLRQALH FQQVFKLAKT 

       370        380        390        400        410        420 
AKFVREEMSF EHMGFGTMNG EDGRPFKTRS GGVVKLIDLL KEADTRALEL VRSKNPDMDE 

       430        440        450        460        470        480 
AELAEIARVV GIASVKYADL SKNRTSDYIF SFEQMLSFEG NTAPYLLYAY TRVAGIFKRA 

       490        500        510        520        530        540 
QDVDLSDAKI VLEHEKEKDL GTKLAQFGEV MNRVVNKGQP HALCAYLFEL AGAFSSFYEA 

       550        560        570        580 
CPVLAADTEA QKKSRLLLAQ LTAKTLKQGL NLLGLETLER M 

« Hide

References

[1]"Environmental adaptation: genomic analysis of the piezotolerant and psychrotolerant deep-sea iron reducing bacterium Shewanella piezotolerans WP3."
Wang F., Wang J., Jian H., Zhang B., Li S., Wang F., Zeng X., Gao L., Bartlett D.H., Yu J., Hu S., Xiao X.
PLoS ONE 3:E1937-E1937(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: WP3 / JCM 13877.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000472 Genomic DNA. Translation: ACJ27305.1.
RefSeqYP_002309892.1. NC_011566.1.

3D structure databases

ProteinModelPortalB8CI29.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING225849.swp_0474.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaACJ27305; ACJ27305; swp_0474.
GeneID7031590.
KEGGswp:swp_0474.
PATRIC23539692. VBIShePie65056_0436.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMANPNGPLH.
OrthoDBEOG6JB13C.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycSPIE225849:GH6V-464-MONOMER.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_SHEPW
AccessionPrimary (citable) accession number: B8CI29
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: March 3, 2009
Last modified: April 16, 2014
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries