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Protein
Submitted name:

2-oxoglutarate dehydrogenase E1 component

Gene

THAPSDRAFT_269718

Organism
Thalassiosira pseudonana (Marine diatom) (Cyclotella nana)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: UniProtKB-EC
  2. thiamine pyrophosphate binding Source: InterPro

GO - Biological processi

  1. tricarboxylic acid cycle Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseImported

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase E1 componentImported (EC:1.2.4.2Imported)
Gene namesi
ORF Names:THAPSDRAFT_269718Imported
OrganismiThalassiosira pseudonana (Marine diatom) (Cyclotella nana)Imported
Taxonomic identifieri35128 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesBacillariophytaCoscinodiscophyceaeThalassiosirophycidaeThalassiosiralesThalassiosiraceaeThalassiosira
ProteomesiUP000001449 Componenti: Chromosome 13

PTM / Processingi

Proteomic databases

PRIDEiB8CBX3.

Interactioni

Protein-protein interaction databases

STRINGi35128.JGI269718.

Structurei

3D structure databases

ProteinModelPortaliB8CBX3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259586.
InParanoidiB8CBX3.
KOiK00164.

Family and domain databases

Gene3Di3.40.50.970. 3 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 3 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.

Sequencei

Sequence statusi: Complete.

B8CBX3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRLSHGSGRH SSSNYISHHG NNSSIIRHLS THPSKNDSFL SASSSLYIES
60 70 80 90 100
MLERYEQDPD SVPESWRTYF EMGAADASTS SSGEEAMFNQ PTIVLSTHLI
110 120 130 140 150
RAYQVNGHRS ANLDPLGLHT NESFPSHDGF AATLNVGFHG FDPNKDMDRE
160 170 180 190 200
LNFKGVHTGG NKGFLEDLTS MPGKVTLRKV LDRLRQTYCG TIGVEYMHIG
210 220 230 240 250
STEQCNWIRE RVEHPSFLQC DREKKIHIYE RLCFADTFEN YMAHKFNTTK
260 270 280 290 300
RFGLDGGEAI VPALKDAIDR ASELGAHSFI IGMPHRGRLN VLANVMRKPM
310 320 330 340 350
TTIFSEFQGT HYEMGYYTKM KEDWGSSGDV KYHLGSSMDR TYPDGRKIHL
360 370 380 390 400
SLVANPSHLE CVNPVVLGKA RAKQFYCGDS DEDMRNVVPI LLHGDAAFAG
410 420 430 440 450
QGVVYETMQM MGVDDFKVGG TLHVIVNNQI GFTTNPINSR STPYASDLGK
460 470 480 490 500
AFNCPIFHCN GDDPVAVSRA LETAVEWRHE WGTDVVIDMI CYRRNGHNEL
510 520 530 540 550
DQPMFTQPKL YKAITRHPST LEIFEKKLIE EGTMSKEEVE EIRAFTLQSY
560 570 580 590 600
ETDYEASKTY KPKPEDWLSS KWSGFKSPRQ HSRIRPTGVD IDTLRYIGNK
610 620 630 640 650
AGEVPEGFKI HRQMNKIFKA RQTMAQEGTE IDWGLAEAMA FGSLLLEGNH
660 670 680 690 700
VRLTGQDVQR GTFSHRHAVV KDQDTEEEYT PLNSLARILS MSAPLEELRL
710 720 730 740 750
PDTQAKLTVR NSILSEFAVL GFEHGYSLEN PNALVLWEAQ FGDFVNGAQV
760 770 780 790 800
MLDQFIAAGE DKWLRQSGLV MLLPHGYDGQ GAEHSSCRVE RYLQMVEEDP
810 820 830 840 850
HHIPPMGKDE RNQIQKVNWQ IVNCTTPANY FHCLRRQIHR DFRKPLIVVA
860 870 880 890 900
PKNLLRNKRC VSSLDDMGPG TIFHRTFDET DEVIKNNPEN VKTLVFCTGQ
910 920 930 940 950
IYYELVGERE KLGRHDVAIV RLEQIAPFAF DKVALYCSKY GNAEVIWAQQ
960 970 980 990 1000
EPKNMGAYSY VLPRLMTATR EINNNEKRAR YVGRLVSSAP ATGMSKIHLK
1010
EYRDIMEGVF GEASE
Length:1,015
Mass (Da):114,945
Last modified:March 3, 2009 - v1
Checksum:i3A7C94E0152488DB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000648 Genomic DNA. Translation: EED89203.1.
RefSeqiXP_002293467.1. XM_002293431.1.

Genome annotation databases

EnsemblProtistsiThaps269718; Thaps269718; Thaps269718.
GeneIDi7450803.
KEGGitps:THAPSDRAFT_269718.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000648 Genomic DNA. Translation: EED89203.1.
RefSeqiXP_002293467.1. XM_002293431.1.

3D structure databases

ProteinModelPortaliB8CBX3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi35128.JGI269718.

Proteomic databases

PRIDEiB8CBX3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiThaps269718; Thaps269718; Thaps269718.
GeneIDi7450803.
KEGGitps:THAPSDRAFT_269718.

Phylogenomic databases

eggNOGiCOG0567.
HOGENOMiHOG000259586.
InParanoidiB8CBX3.
KOiK00164.

Family and domain databases

Gene3Di3.40.50.970. 3 hits.
InterProiIPR011603. 2oxoglutarate_DH_E1.
IPR001017. DH_E1.
IPR029061. THDP-binding.
IPR005475. Transketolase-like_Pyr-bd.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.
PfamiPF00676. E1_dh. 1 hit.
PF02779. Transket_pyr. 1 hit.
[Graphical view]
PIRSFiPIRSF000157. Oxoglu_dh_E1. 1 hit.
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 3 hits.
TIGRFAMsiTIGR00239. 2oxo_dh_E1. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CCMP1335Imported.
  2. Cited for: GENOME REANNOTATION.
    Strain: CCMP1335Imported.

Entry informationi

Entry nameiB8CBX3_THAPS
AccessioniPrimary (citable) accession number: B8CBX3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: January 7, 2015
This is version 37 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.