B8A691 (B8A691_DANRE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Toll-like receptor PIRNR PIRNR037595

Gene names

Name:	tlr4bb Ensembl ENSDARP00000028819 ZFIN ZDB-GENE-040219-9
Synonyms:	tlr4b EMBL CAX12073.1 ZFIN ZDB-GENE-040219-9
ORF Names:	CH211-198A12.2-001 EMBL CAX12073.1

Organism

Danio rerio (Zebrafish) (Brachydanio rerio) EMBL CAX12073.1

Taxonomic identifier

7955 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio

Protein attributes

Sequence length	819 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the Toll-like receptor family. PIRNR PIRNR037595 Contains 1 TIR domain. SAAS SAAS000157

Ontologies

Keywords
Biological process	Immunity Inflammatory response PIRNR PIRNR037595 Innate immunity PIRNR PIRNR037595
Molecular function	Receptor PIRNR PIRNR037595 EMBL CAX12073.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	inflammatory response Inferred from electronic annotation. Source: UniProtKB-KW innate immune response Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro intracellular Inferred from electronic annotation. Source: InterPro
Molecular function	transmembrane signaling receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B8A691 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 8CF8B0CED03E165E	FASTA	819	94,654
	10 20 30 40 50 60 MIMSNGERMI FLSSIFILVN AGQGQECTEL IKNKEYSCSG RNLTCIPGSL PFSVASLDFS 70 80 90 100 110 120 FNFLTSLHKR VFPVMLNLQL LDLTRCYIRQ IEKDAFYNVK NLMTLILTGN PITYLAPECL 130 140 150 160 170 180 NSLYKLQRLV LVDVRLESLQ LQINNLTKLQ DLKVGTNCIQ SMTLPSFMST FKDFSLLDLH 190 200 210 220 230 240 ANNISIIRMD HTAVLREIGR NMTLILSRNP LIHIEPGAFK DVILRELHLL AAFISFNAQK 250 260 270 280 290 300 ECHKALTGLT VDKLFVGRYR MDEKIKVSVP DYLEGLCSIN FNEIYLVQKE WSDSEMHLFR 310 320 330 340 350 360 CMVNATKITI KKAYMNSMKH IPFHRLKELY LSDTGLSVVP FISHIPSLEK LVMKSPFPIT 370 380 390 400 410 420 FTGVSDLPLL QYVDLSGNML ILHECCSILF PRTPNIQYLN LSQNSEITFV NEPFSALDLL 430 440 450 460 470 480 EVLDFHHTKL VIVFYFGFFK HLRNLKYLDI SYTRVHFNTL TFQDLHNLTV LKMAGNSFSG 490 500 510 520 530 540 DKLSYFLQNL TSLEVLDISQ CGIEKVSMRS FTGTQKLRHL YLSRNKLMVL DFLTQPELTH 550 560 570 580 590 600 LTSVYIDKNS ITTIPLDVLQ KLPMNLSEFD LSSNSIDCSC SQTDFILWII QKQNILKQLE 610 620 630 640 650 660 NIRCKTFSAN TDFKAIDFDI DYCVHKKRLT IVLSVICVTF VVVLAILLYK FWFYVQYCFI 670 680 690 700 710 720 LFSGYRSPGQ QECSYDAFVI FSSYDEAWVM NELMENLENG VPPIQLCLHM RDFQAGKSIA 730 740 750 760 770 780 SNIIDEGIMG SRKIIVVVSQ HFIDSSWCRF EFELAQSRFL MERNANIIII ILEDVAERKT 790 800 810 KKVFGLHKHL KKNTYLKWSR DPLSNMRFWI RLRKAILQK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Corby N. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The genomic sequence of Danio rerio." The Danio rerio Sequencing Project at the Sanger Institute Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen Ensembl ENSDARP00000028819.
[3]	Ensembl Submitted (JUL-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: Tuebingen Ensembl ENSDARP00000028819.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX908770 Genomic DNA. Translation: CAX12073.1.
IPI	IPI00484361.
UniGene	Dr.89442.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSDART00000034852; ENSDARP00000028819; ENSDARG00000022048.
Organism-specific databases
ZFIN	ZDB-GENE-040219-9. tlr4bb.
Phylogenomic databases
HOGENOM	HBG278305.
HOVERGEN	HBG018823.
OMA	DISSCKL.
OrthoDB	EOG4P8FHQ.
PhylomeDB	B8A691.
Gene expression databases
Bgee	B8A691.
Family and domain databases
InterPro	IPR000157. TIR_dom. IPR017241. Toll-like_receptor. [Graphical view]
Pfam	PF01582. TIR. 1 hit. [Graphical view]
PIRSF	PIRSF037595. Toll-like_receptor. 1 hit.
SMART	SM00255. TIR. 1 hit. [Graphical view]
SUPFAM	SSF52200. TIR. 1 hit.
PROSITE	PS50104. TIR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

B8A691_DANRE

Accession

Primary (citable) accession number: B8A691

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	January 25, 2012
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)