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B8A5H6

- B8A5H6_DANRE

UniProt

B8A5H6 - B8A5H6_DANRE

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Protein
Submitted name: Uncharacterized protein
Gene
hkdc1
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. fructokinase activity Source: RefGenome
  3. glucokinase activity Source: RefGenome
  4. mannokinase activity Source: RefGenome

GO - Biological processi

  1. carbohydrate phosphorylation Source: GOC
  2. cellular glucose homeostasis Source: RefGenome
  3. glucose 6-phosphate metabolic process Source: GOC
  4. glycolytic process Source: RefGenome
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotations, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotations

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotations, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:hkdc1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
ProteomesiUP000000437: Chromosome 13

Organism-specific databases

ZFINiZDB-GENE-030131-9801. hkdc1.

Subcellular locationi

GO - Cellular componenti

  1. cytosol Source: RefGenome
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000056522.

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG5026.
GeneTreeiENSGT00390000017159.
HOGENOMiHOG000162671.
HOVERGENiHBG005020.
KOiK00844.
OMAiVKMLPTH.
OrthoDBiEOG7S21X5.
PhylomeDBiB8A5H6.
TreeFamiTF314238.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B8A5H6-1 [UniParc]FASTAAdd to Basket

« Hide

MFAVHLLSFY FSKLQEDQIK KVDRFLYAMR LSEDQLKDIS ARFRLEMEKG    50
LSSESNAAAA VKMLPTHVYS TPDGSEKGEF LALDLGGSKF KVLQVKVSED 100
GKGKVEMESE TFPIPEEIVN GRGTELFEHV AESLKSFLQK HHINHTRKPL 150
GFTFSFPCAQ SKIDEGVLLS WSKNFKVRGV QGTNVVQSLR KAIRKVGDLD 200
VDVLAMVNDT VGAMMTCGYD DQNCEVGVIV GTGTNACYME EMRHIDLVEG 250
DEGRMCINTE LGAFGDDGVL DDFITSFDRE IDAASINPGK QLFEKMVSGM 300
YMGELVRLIL LRMAKKGLLF RGQISDALRT KGTFHTNHMC LIEQYKSGLE 350
NTKEILEDLG LNPSDDDCIA VQHVCTIVSF RSANLVAAAL AAILTRIREN 400
KKLKTLRTTV GVDGTVYRTH PQYPKRLHKV VRHLVPDCHV RFVLSESGSA 450
KGAAMVTAVA QRLASQRKEI DDTLAAFALT STQLQEVKQK MHVELERGLK 500
KETHPTASVK MLPTYVYRTP DGTERGKYLA LDLGGTNFRV LVVKIRTGMR 550
NSVRMYNKIY AIPLEIMQGT GEELFDHIVQ CISDFLDYMG MKNTRLPLGF 600
TFSFPCNQTG IDKGDLVCWT KGFKATDCEG YDVVDMLREA IKRRNEFDLD 650
IVAIVNDTVG TMMTCAYEDP KCQIGLIAGT GSNVCYMEEM KNIEIVEGDE 700
GQMCVNTEWG GFGENDNIED IRTRYDREVD SGSLNAGKQR FEKMTSGMYL 750
GEIVRQILID LTKRGFLFRG RITERLKTKG IFETKFLSQI ESDRLALLQV 800
RCILQSLGLD STCDDSIIVK EVCGAVSRRA AQLCGAGMAA IVDKIRENRG 850
LDRLDITVGV DGTLYKLHPH FSTILKETVR ELAPNCKVDF ILSEDGSGKG 900
AALITAVARQ HHVQKQEQN 919
Length:919
Mass (Da):102,548
Last modified:March 3, 2009 - v1
Checksum:iE06A9CAC14BF6FDB
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX546482 Genomic DNA. No translation available.
RefSeqiNP_001108597.1. NM_001115125.1.
UniGeneiDr.34012.

Genome annotation databases

EnsembliENSDART00000056523; ENSDARP00000056522; ENSDARG00000038703.
GeneIDi321224.
KEGGidre:321224.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX546482 Genomic DNA. No translation available.
RefSeqi NP_001108597.1. NM_001115125.1.
UniGenei Dr.34012.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 7955.ENSDARP00000056522.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSDART00000056523 ; ENSDARP00000056522 ; ENSDARG00000038703 .
GeneIDi 321224.
KEGGi dre:321224.

Organism-specific databases

CTDi 80201.
ZFINi ZDB-GENE-030131-9801. hkdc1.

Phylogenomic databases

eggNOGi COG5026.
GeneTreei ENSGT00390000017159.
HOGENOMi HOG000162671.
HOVERGENi HBG005020.
KOi K00844.
OMAi VKMLPTH.
OrthoDBi EOG7S21X5.
PhylomeDBi B8A5H6.
TreeFami TF314238.

Miscellaneous databases

NextBioi 20807291.
PROi B8A5H6.

Family and domain databases

InterProi IPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view ]
PANTHERi PTHR19443. PTHR19443. 1 hit.
Pfami PF00349. Hexokinase_1. 2 hits.
PF03727. Hexokinase_2. 2 hits.
[Graphical view ]
PRINTSi PR00475. HEXOKINASE.
PROSITEi PS00378. HEXOKINASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The zebrafish reference genome sequence and its relationship to the human genome."
    Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.
    , White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.
    Nature 496:498-503(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: TuebingenImported.
  2. Ensembl
    Submitted (AUG-2013) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: TuebingenImported.

Entry informationi

Entry nameiB8A5H6_DANRE
AccessioniPrimary (citable) accession number: B8A5H6
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 9, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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