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Protein

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Gene

100279930

Organism
Zea mays (Maize)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).UniRule annotation

Catalytic activityi

Succinate + a quinone = fumarate + a quinol.UniRule annotation

Cofactori

FADUniRule annotation

Pathwayi: tricarboxylic acid cycle

This protein is involved in step 1 of the subpathway that synthesizes fumarate from succinate (eukaryal route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (100280324), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial, Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (100216648), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (sdh2-rps14), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (100502233), Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial (100279930), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (100216648), Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial (sdh2-rps14)
This subpathway is part of the pathway tricarboxylic acid cycle, which is itself part of Carbohydrate metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes fumarate from succinate (eukaryal route), the pathway tricarboxylic acid cycle and in Carbohydrate metabolism.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductaseUniRule annotation
Biological processElectron transportUniRule annotation, Transport, Tricarboxylic acid cycleUniRule annotation
LigandFADUniRule annotation, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00223; UER01006

Names & Taxonomyi

Protein namesi
Recommended name:
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrialUniRule annotation (EC:1.3.5.1UniRule annotation)
Gene namesi
Name:100279930Imported
ORF Names:ZEAMMB73_Zm00001d018758Imported
OrganismiZea mays (Maize)Imported
Taxonomic identifieri4577 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaLiliopsidaPoalesPoaceaePACMAD cladePanicoideaeAndropogonodaeAndropogoneaeTripsacinaeZea
Proteomesi
  • UP000007305 Componenti: Chromosome 7

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MembraneUniRule annotation

PTM / Processingi

Proteomic databases

PaxDbiB8A0Q6
PRIDEiB8A0Q6

Expressioni

Gene expression databases

ExpressionAtlasiB8A0Q6 differential

Interactioni

Protein-protein interaction databases

STRINGi4577.GRMZM2G064799_P01

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini36 – 432FAD_binding_2InterPro annotationAdd BLAST397
Domaini487 – 619Succ_DH_flav_CInterPro annotationAdd BLAST133

Sequence similaritiesi

Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.UniRule annotation

Keywords - Domaini

Transit peptideUniRule annotation

Phylogenomic databases

eggNOGiKOG2403 Eukaryota
COG1053 LUCA
KOiK00234
OMAiGDSPWEH
OrthoDBiEOG093604YT

Family and domain databases

Gene3Di3.50.50.60, 2 hits
3.90.700.10, 1 hit
InterProiView protein in InterPro
IPR003953 FAD-binding_2
IPR036188 FAD/NAD-bd_sf
IPR003952 FRD_SDH_FAD_BS
IPR037099 Fum_R/Succ_DH_flav-like_C_sf
IPR015939 Fum_Rdtase/Succ_DH_flav-like_C
IPR027477 Succ_DH/fumarate_Rdtase_cat_sf
IPR011281 Succ_DH_flav_su_fwd
IPR014006 Succ_Dhase_FrdA_Gneg
PfamiView protein in Pfam
PF00890 FAD_binding_2, 1 hit
PF02910 Succ_DH_flav_C, 1 hit
SUPFAMiSSF46977 SSF46977, 1 hit
SSF51905 SSF51905, 2 hits
SSF56425 SSF56425, 1 hit
TIGRFAMsiTIGR01816 sdhA_forward, 1 hit
TIGR01812 sdhA_frdA_Gneg, 1 hit
PROSITEiView protein in PROSITE
PS00504 FRD_SDH_FAD_BINDING, 1 hit

Sequencei

Sequence statusi: Complete.

B8A0Q6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRSCVSRGL SRAKASASRL LSTASSSYTV VDHTYDAVVV GAGGAGLRAA
60 70 80 90 100
IGLSEHGFNT ACITKLFPTR SHTVAAQGGI NAALGNMSED DWRWHMYDTV
110 120 130 140 150
KGSDWLGDQD SIQYMCREAP KAVIELENYG LPFSRTEEGK IYQRAFGGQS
160 170 180 190 200
LDFGKGGQAY RCACAADRTG HAMLHTLYGQ AMKHNTQFFV EYFALDLLMD
210 220 230 240 250
NEGKCQGIIA LNMEDGTLHR FRASNTILAT GGYGRAYFSA TSAHTCTGDG
260 270 280 290 300
NAMVARAGLP LQDLEFVQFH PTGIYGAGCL ITEGSRGEGG ILRNSEGERF
310 320 330 340 350
MERYAPTAKD LASRDVVSRS MTMEIREGRG VGPLKDHIYL HLNHLPPEVL
360 370 380 390 400
KERLPGISET AAIFAGVDVT KEPIPVLPTV HYNMGGIPTN YHGEVVDIKG
410 420 430 440 450
DNPDAVVPGL MAAGEAACAS VHGANRLGAN SLLDIVVFGR ACANRVADIS
460 470 480 490 500
KPGEKQKPLE KDAGEKTIAW LDKLRNANGS LPTSKIRLNM QRVMQNNAAV
510 520 530 540 550
FRTQETLEEG CELISKTWES FHDVKLSDQS LIWNSDLIET LELENLLINA
560 570 580 590 600
CITMYSAEAR KESRGAHARE DFTTRDDEKW MKHSLGYWEN EKVRLAYRPV
610
HMNTLDDEVE SFPPKARVY
Length:619
Mass (Da):67,970
Last modified:March 3, 2009 - v1
Checksum:i8A89F70D0AEDE61C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT055148 mRNA Translation: ACL53755.1
BT069258 mRNA Translation: ACN36155.1
BT069259 mRNA Translation: ACN36156.1
CM007650 Genomic DNA Translation: ONM51239.1
CM007650 Genomic DNA Translation: ONM51240.1
RefSeqiNP_001146352.1, NM_001152880.1
UniGeneiZm.16130

Genome annotation databases

EnsemblPlantsiZm00001d018758_T002; Zm00001d018758_P002; Zm00001d018758
Zm00001d018758_T003; Zm00001d018758_P003; Zm00001d018758
GeneIDi100279930
GrameneiZm00001d018758_T002; Zm00001d018758_P002; Zm00001d018758
Zm00001d018758_T003; Zm00001d018758_P003; Zm00001d018758
KEGGizma:100279930

Similar proteinsi

Entry informationi

Entry nameiB8A0Q6_MAIZE
AccessioniPrimary (citable) accession number: B8A0Q6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 69 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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