Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CCR4-NOT transcription complex subunit 1

Gene

Cnot1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CCR4-NOT transcription complex subunit 1Imported
Submitted name:
Cnot1 proteinImported
Gene namesi
Name:Cnot1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 8

Organism-specific databases

MGIiMGI:2442402. Cnot1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063565.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini501 – 656156CNOT1_HEATInterPro annotationAdd
BLAST
Domaini816 – 998183CNOT1_TTP_bindInterPro annotationAdd
BLAST
Domaini1084 – 1306223CNOT1_CAF1_bindInterPro annotationAdd
BLAST
Domaini1382 – 1529148DUF3819InterPro annotationAdd
BLAST
Domaini1993 – 2303311Not1InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiKOG1831. Eukaryota.
COG5103. LUCA.
GeneTreeiENSGT00390000014869.
HOVERGENiHBG060834.

Family and domain databases

InterProiIPR007196. CCR4-Not_Not1_C.
IPR024557. CCR4-Not_Not1su_DUF3819.
IPR032191. CNOT1_CAF1_bind.
IPR032194. CNOT1_HEAT.
IPR032193. CNOT1_TTP_bind.
[Graphical view]
PfamiPF16415. CNOT1_CAF1_bind. 1 hit.
PF16418. CNOT1_HEAT. 1 hit.
PF16417. CNOT1_TTP_bind. 1 hit.
PF12842. DUF3819. 1 hit.
PF04054. Not1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7ZWL1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLDSLSLAL SQISYLVDNL TKKNYRASQQ EIQHIVNRHG PEADRHLLRC
60 70 80 90 100
LFSHVDFSGD GKSSGKDFHQ TQFLIQECAS LITKPNFIST LSYAIDNPLH
110 120 130 140 150
YQKSLKPAPH LFAQLSKVLK LSKVQEVIFG LALLNSSSPD LRGFAAQFIK
160 170 180 190 200
QKLPDLLRSY IDADVSGNQE GGFQDIAIEV LHLLLSHLLF GQKGAFGVGQ
210 220 230 240 250
EQIDAFLKTL RRDFPQERCP VVLAPLLYPE KRDILMDRIL PDSGGVAKTM
260 270 280 290 300
MESSLADFMQ EVGYGFCASI EECRNIIMQF GVREVTAAQV ARVLGMMART
310 320 330 340 350
HSGLTDGIPL QSISAPGSGI WSDGKDKSEG AQAHTWNVEV LIDVLKELNP
360 370 380 390 400
SLNFKEVTYE LDHPGFQIRD SKGLHNVVYG IQRGLGMEVF PVDFIYRPWK
410 420 430 440 450
HAEGQLSFIQ HSLINPEVFC FADYPCHTVA TDILKAPPED DNREIATWKS
460 470 480 490 500
LDLIESLLRL AEVGQYEQVK QLFSFPIKHC PDMLVLALLQ INTSWHTLRH
510 520 530 540 550
ELISTLMPIF LGNHPNSAII LHYAWHGQGQ SPSIRQLIMH AMAEWYMRGE
560 570 580 590 600
QYDQAKLSRI LDVAQDLKAL SMLLNGTPFA FVIDLAALAS RREYLKLDKW
610 620 630 640 650
LTDKIREHGE PFIQACMTFL KRRCPSILGG LAPEKDQPKS AQLPAETLAT
660 670 680 690 700
MLACLQACAG SVSQELSETI LTMVANCSNV MNKARQPPPG VMPKGRPPSA
710 720 730 740 750
SSLDAISPVQ IDPLAGMASL SIGGSAAPHT QSMQGFPPNL GSAFSTPQSP
760 770 780 790 800
AKAFPPLSTP NQTTAFSGIG GLSSQLPVGG LGTGSLTGIG TGALGLPAVN
810 820 830 840 850
NDPFVQRKLG TSGLNQPTFQ QTDLSQVWPE ANQHFSKEID DEANSYFQRI
860 870 880 890 900
YNHPPHPTMS VDEVLEMLQR FKDSTIKRER EVFNCMLRNL FEEYRFFPQY
910 920 930 940 950
PDKELHITAC LFGGIIEKGL VTYMALGLAL RYVLEALRKP FGSKMYYFGI
960 970 980 990 1000
AALDRFKNRL KDYPQYCQHL ASISHFMQFP HHLQEYIEYG QQSRDPPVKM
1010 1020 1030 1040 1050
QGSITTPGSI ALAQAQAQAQ VPAKAPLAGQ VNTMVTTSTT TTVAKTVTVT
1060 1070 1080 1090 1100
KPTGVSFKKD VPPSINTTNI DTLLVATDQT ERIVEPPENI QEKIAFIFNN
1110 1120 1130 1140 1150
LSQSNMTQKV EELKETVKEE FMPWVSQYLV MKRVSIEPNF HSLYSNFLDT
1160 1170 1180 1190 1200
LKNPEFNKMV LNETYRNIKV LLTSDKAAAN FSDRSLLKNL GHWLGMITLA
1210 1220 1230 1240 1250
KNKPILHTDL DVKSLLLEAY VKGQQELLYV VPFVAKVLES SIRSLVFRPP
1260 1270 1280 1290 1300
NPWTMAIMNV LAELHQEHDL KLNLKFEIEV LCKNLALDIN ELKPGNLLKD
1310 1320 1330 1340 1350
KDRLKNLDEQ LSAPKKDVKQ PEELPAITTT TTSTTPATST TCTATVPPQP
1360 1370 1380 1390 1400
QYSYHDINVY SLAGLAPHIT LNPTIPLFQA HPQLKQCVRQ AIERAVQELV
1410 1420 1430 1440 1450
HPVVDRSIKI AMTTCEQIVR KDFALDSEES RMRIAAHHMM RNLTAGMAMI
1460 1470 1480 1490 1500
TCREPLLMSI STNLKNSFAS ALRTASPQQR EMMDQAAAQL AQDNCELACC
1510 1520 1530 1540 1550
FIQKTAVEKA GPEMDKRLAT EFELRKHARQ EGRRYCDPVV LTYQAERMPE
1560 1570 1580 1590 1600
QIRLKVGGVD PKQLAVYEEF ARNVPGFLPT NDLSQPTGFL AQPMKQAWAT
1610 1620 1630 1640 1650
DDVAQIYDKC ITELEQHLHA IPPTLAMNPQ AQALRSLLEV VVLSRNSRDA
1660 1670 1680 1690 1700
IAALGLLQKA VEGLLDATSG ADADLLLRYR ECHLLVLKAL QDGRAYGSPW
1710 1720 1730 1740 1750
CNKQITRCLI ECRDEYKYNV EAVELLIRNH LVNMQQYDLH LAQSMENGLN
1760 1770 1780 1790 1800
YMAVAFAMQL VKILLVDERS VAHITEADLF HTIETLMRIN AHSRGNAPEG
1810 1820 1830 1840 1850
LPQLMEVVRS NYEAMIDRAH GGPNFMMHSG ISQASEYDDP PGLREKAEYL
1860 1870 1880 1890 1900
LREWVNLYHS AAAGRDSTKA FSAFVGQMHQ QGILKTDDLI TRFFRLCTEM
1910 1920 1930 1940 1950
CVEISYRAQA EQQHNPAANP TMIRAKCYHN LDAFVRLIAL LVKHSGEATN
1960 1970 1980 1990 2000
TVTKINLLNK VLGIVVGVLL QDHDVRQSEF QQLPYHRIFI MLLLELNAPE
2010 2020 2030 2040 2050
HVLETINFQT LTAFCNTFHI LRPTKAPGFV YAWLELISHR IFIARMLAHT
2060 2070 2080 2090 2100
PQQKGWPMYA QLLIDLFKYL APFLRNVELT KPMQILYKGT LRVLLVLLHD
2110 2120 2130 2140 2150
FPEFLCDYHY GFCDVIPPNC IQLRNLILSA FPRNMRLPDP FTPNLKVDML
2160 2170 2180 2190 2200
SEINIAPRIL TNFTGVMPPQ FKKDLDSYLK TRSPVTFLSD LRSNLQVSNE
2210 2220 2230 2240 2250
PGNRYNLQLI NALVLYVGTQ AIAHIHNKGS TPSMSTITHS AHMDIFQNLA
2260 2270 2280 2290 2300
VDLDTEGRYL FLNAIANQLR YPNSHTHYFS CTMLYLFAEA NTEAIQEQIT
2310 2320
RLFQSVAQCC MGQKQAQQVM EGTGAS
Length:2,326
Mass (Da):260,958
Last modified:March 3, 2009 - v1
Checksum:i72E0E89463918288
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113951 Genomic DNA. No translation available.
AC127300 Genomic DNA. No translation available.
BC172105 mRNA. Translation: AAI72105.1.
RefSeqiNP_694804.3. NM_153164.3.
UniGeneiMm.259220.

Genome annotation databases

EnsembliENSMUST00000068452; ENSMUSP00000063565; ENSMUSG00000036550.
GeneIDi234594.
UCSCiuc012gis.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC113951 Genomic DNA. No translation available.
AC127300 Genomic DNA. No translation available.
BC172105 mRNA. Translation: AAI72105.1.
RefSeqiNP_694804.3. NM_153164.3.
UniGeneiMm.259220.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000063565.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000068452; ENSMUSP00000063565; ENSMUSG00000036550.
GeneIDi234594.
UCSCiuc012gis.2. mouse.

Organism-specific databases

CTDi23019.
MGIiMGI:2442402. Cnot1.

Phylogenomic databases

eggNOGiKOG1831. Eukaryota.
COG5103. LUCA.
GeneTreeiENSGT00390000014869.
HOVERGENiHBG060834.

Miscellaneous databases

ChiTaRSiCnot1. mouse.
SOURCEiSearch...

Family and domain databases

InterProiIPR007196. CCR4-Not_Not1_C.
IPR024557. CCR4-Not_Not1su_DUF3819.
IPR032191. CNOT1_CAF1_bind.
IPR032194. CNOT1_HEAT.
IPR032193. CNOT1_TTP_bind.
[Graphical view]
PfamiPF16415. CNOT1_CAF1_bind. 1 hit.
PF16418. CNOT1_HEAT. 1 hit.
PF16417. CNOT1_TTP_bind. 1 hit.
PF12842. DUF3819. 1 hit.
PF04054. Not1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB7ZWL1_MOUSE
AccessioniPrimary (citable) accession number: B7ZWL1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 8, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.