Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Transmembrane protein 92

Gene

Tmem92

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Transmembrane protein 92
Gene namesi
Name:Tmem92
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:3034723. Tmem92.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini23 – 63ExtracellularSequence analysisAdd BLAST41
Transmembranei64 – 84HelicalSequence analysisAdd BLAST21
Topological domaini85 – 162CytoplasmicSequence analysisAdd BLAST78

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000041612023 – 162Transmembrane protein 92Add BLAST140

Proteomic databases

PaxDbiB7ZWI3.
PRIDEiB7ZWI3.

Expressioni

Gene expression databases

BgeeiENSMUSG00000075610.
ExpressionAtlasiB7ZWI3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000125159.

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi104 – 150Pro-richAdd BLAST47

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG410J3FY. Eukaryota.
ENOG41117DU. LUCA.
GeneTreeiENSGT00390000014943.
HOGENOMiHOG000133046.
HOVERGENiHBG084496.
InParanoidiB7ZWI3.
OMAiSFRPEKY.
OrthoDBiEOG091G11G2.
TreeFamiTF338534.

Family and domain databases

InterProiView protein in InterPro
IPR021684. WBP1-like.
PfamiView protein in Pfam
PF11669. WBP-1. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: B7ZWI3-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLDTWVWGTL TLTFGLLSSL QGVSFNETAN TCDILNCPKG FTCCVKECCP
60 70 80 90 100
ERKVWDPAND RFRFLVILAC IIFPILFICA LVSLFCPNCT ELQHDVRRVD
110 120 130 140 150
HQTPIEPPSI APLESIWVTS LDPPPPYSQV VQMTPPTEPP PPYSLRPEGP
160
AGQMRGRAYA TL
Length:162
Mass (Da):18,079
Last modified:March 3, 2009 - v1
Checksum:iC8399F19809FB143
GO
Isoform 2 (identifier: B7ZWI3-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     83-130: Missing.

Note: No experimental confirmation available.
Show »
Length:114
Mass (Da):12,686
Checksum:i42426BEDDC94EC33
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_04250783 – 130Missing in isoform 2. 1 PublicationAdd BLAST48

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK139848 mRNA. Translation: BAE24159.1.
AL645764 Genomic DNA. No translation available.
BC172064 mRNA. Translation: AAI72064.1.
CCDSiCCDS36285.1. [B7ZWI3-2]
CCDS48890.1. [B7ZWI3-1]
RefSeqiNP_001030068.1. NM_001034896.2. [B7ZWI3-2]
NP_001156644.1. NM_001163172.1. [B7ZWI3-1]
UniGeneiMm.379774.

Genome annotation databases

EnsembliENSMUST00000100554; ENSMUSP00000128300; ENSMUSG00000075610. [B7ZWI3-2]
ENSMUST00000162809; ENSMUSP00000125159; ENSMUSG00000075610. [B7ZWI3-1]
GeneIDi544806.
KEGGimmu:544806.
UCSCiuc007kzl.1. mouse. [B7ZWI3-2]
uc029rno.1. mouse. [B7ZWI3-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiTMM92_MOUSE
AccessioniPrimary (citable) accession number: B7ZWI3
Secondary accession number(s): E9Q2K3, Q3UT21
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 21, 2012
Last sequence update: March 3, 2009
Last modified: May 10, 2017
This is version 50 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot