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Protein
Submitted name:

ZFP57 protein

Gene

ZFP57

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. nucleic acid binding Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
ZFP57 proteinImported
Gene namesi
Name:ZFP57Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. intracellular Source: InterPro
Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134937821.

PTM / Processingi

Proteomic databases

PaxDbiB7ZW61.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000366080.

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotation, Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiNOG267305.
HOGENOMiHOG000155778.
HOVERGENiHBG108764.
KOiK09228.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR001909. Krueppel-associated_box.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 7 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7ZW61-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFEQLKPIEP VQKTLPWVGE VAATLQEAMK RDCWREARVK KKPVTFEDVA
60 70 80 90 100
VNFTQEEWDC LDASQRVLYQ DVMSETFKNL TSVARIFLHK PELITKLEQE
110 120 130 140 150
EEQWREFVHL PNTEGLSEGK KKELREQHPS LRDEGTSDDK VFLACRGAGQ
160 170 180 190 200
CPLSAPAGTM DRTRVLQASQ AGPPFFCYTC DKCFSRRSYL YSHQFVHNPK
210 220 230 240 250
LTNSCSQCGK LFRSPKSLSY HRRMHLGERP FCCTLCDKTY CDASGLSRHR
260 270 280 290 300
RVHLGYRPHS CSVCGKSFRD QSELKRHQKI HQNQEPVDGN QECTLRIPGT
310 320 330 340 350
QAEFQTPIAR SQGSIQGLLD VNHAPVARSQ EPIFRTEGPM AQNQASVLKN
360 370 380 390 400
QAPVTRTQAP ITGTLCQDAR SNSHPVKPSR LNVFCCPHCS LTFSKKSYLS
410 420 430 440 450
RHQKAHLTEP PNYCFHCSKS FSSFSRLVRH QQTHWKQKSY LCPICDLSFG
460 470 480 490 500
EKEGLMDHWR GYKGKDLCQS SHHKCRVILG QWLGFSHDVP TMAGEEWKHG
510 520 530
GDQSPPRIHT PRRRGLREKA CKGDKTKEAV SILKHK
Length:536
Mass (Da):61,317
Last modified:March 3, 2009 - v1
Checksum:i6321DDFF0A6ED77B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC171888 mRNA. Translation: AAI71888.1.
RefSeqiNP_001103279.2. NM_001109809.2.
UniGeneiHs.156326.

Genome annotation databases

GeneIDi346171.
KEGGihsa:346171.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC171888 mRNA. Translation: AAI71888.1.
RefSeqiNP_001103279.2. NM_001109809.2.
UniGeneiHs.156326.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000366080.

Proteomic databases

PaxDbiB7ZW61.

Protocols and materials databases

DNASUi346171.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi346171.
KEGGihsa:346171.

Organism-specific databases

CTDi346171.
PharmGKBiPA134937821.

Phylogenomic databases

eggNOGiNOG267305.
HOGENOMiHOG000155778.
HOVERGENiHBG108764.
KOiK09228.

Miscellaneous databases

GenomeRNAii346171.
NextBioi98937.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR001909. Krueppel-associated_box.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF00096. zf-C2H2. 2 hits.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00355. ZnF_C2H2. 7 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 6 hits.
PS50157. ZINC_FINGER_C2H2_2. 7 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].

Entry informationi

Entry nameiB7ZW61_HUMAN
AccessioniPrimary (citable) accession number: B7ZW61
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 1, 2015
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.