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Protein
Submitted name:

Fibronectin

Gene

Fn1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
FibronectinImported
Submitted name:
Fn1 proteinImported
Gene namesi
Name:Fn1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:95566. Fn1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2727Sequence analysisAdd
BLAST
Chaini28 – 21762149Sequence analysisPRO_5007644915Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PeptideAtlasiB7ZNJ1.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini51 – 9141Fibronectin type-IInterPro annotationAdd
BLAST
Domaini96 – 13944Fibronectin type-IInterPro annotationAdd
BLAST
Domaini140 – 18344Fibronectin type-IInterPro annotationAdd
BLAST
Domaini185 – 22945Fibronectin type-IInterPro annotationAdd
BLAST
Domaini230 – 27445Fibronectin type-IInterPro annotationAdd
BLAST
Domaini306 – 34540Fibronectin type-IInterPro annotationAdd
BLAST
Domaini355 – 40349Fibronectin type-IIInterPro annotationAdd
BLAST
Domaini415 – 46349Fibronectin type-IIInterPro annotationAdd
BLAST
Domaini468 – 51144Fibronectin type-IInterPro annotationAdd
BLAST
Domaini516 – 55843Fibronectin type-IInterPro annotationAdd
BLAST
Domaini559 – 60244Fibronectin type-IInterPro annotationAdd
BLAST
Domaini610 – 717108Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini721 – 81191Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini812 – 90392Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini908 – 99790Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini998 – 108790Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1088 – 117487Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1175 – 126591Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1268 – 136093Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1361 – 144888Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1449 – 154294Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1543 – 163391Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1634 – 172390Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1725 – 181389Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1814 – 190491Fibronectin type-IIIInterPro annotationAdd
BLAST
Domaini1993 – 203745Fibronectin type-IInterPro annotationAdd
BLAST
Domaini2038 – 208043Fibronectin type-IInterPro annotationAdd
BLAST
Domaini2082 – 212241Fibronectin type-IInterPro annotationAdd
BLAST

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00830000128240.
HOVERGENiHBG005731.

Family and domain databases

Gene3Di2.10.10.10. 2 hits.
2.60.40.10. 15 hits.
InterProiIPR000083. Fibronectin_type1.
IPR003961. FN3_dom.
IPR000562. FN_type2_col-bd.
IPR013783. Ig-like_fold.
IPR013806. Kringle-like.
[Graphical view]
PfamiPF00039. fn1. 12 hits.
PF00040. fn2. 2 hits.
PF00041. fn3. 15 hits.
[Graphical view]
SMARTiSM00058. FN1. 12 hits.
SM00059. FN2. 2 hits.
SM00060. FN3. 15 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 9 hits.
SSF57440. SSF57440. 2 hits.
PROSITEiPS01253. FN1_1. 12 hits.
PS51091. FN1_2. 12 hits.
PS00023. FN2_1. 2 hits.
PS51092. FN2_2. 2 hits.
PS50853. FN3. 14 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7ZNJ1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRGPGPGRL LLLAVLCLGT SVRCTEAGKS KRQAQQIVQP QSPVAVSQSK
60 70 80 90 100
PGCFDNGKHY QINQQWERTY LGNALVCTCY GGSRGFNCES KPEPEETCFD
110 120 130 140 150
KYTGNTYKVG DTYERPKDSM IWDCTCIGAG RGRISCTIAN RCHEGGQSYK
160 170 180 190 200
IGDKWRRPHE TGGYMLECLC LGNGKGEWTC KPIAEKCFDH AAGTSYVVGE
210 220 230 240 250
TWEKPYQGWM MVDCTCLGEG NGRITCTSRN RCNDQDTRTS YRIGDTWSKK
260 270 280 290 300
DNRGNLLQCV CTGNGRGEWK CERHALQSAS AGSGSFTDVR TAIYQPQTHP
310 320 330 340 350
QPAPYGHCVT DSGVVYSVGM QWLKSQGNKQ MLCTCLGNGV SCQETAVTQT
360 370 380 390 400
YGGNSNGEPC VLPFTYNGRT FYSCTTEGRQ DGHLWCSTTS NYEQDQKYSF
410 420 430 440 450
CTDHAVLVQT RGGNSNGALC HFPFLYNNRN YTDCTSEGRR DNMKWCGTTQ
460 470 480 490 500
NYDADQKFGF CPMAAHEEIC TTNEGVMYRI GDQWDKQHDL GHMMRCTCVG
510 520 530 540 550
NGRGEWACIP YSQLRDQCIV DDITYNVNDT FHKRHEEGHM LNCTCFGQGR
560 570 580 590 600
GRWKCDPIDQ CQDSETRTFY QIGDSWEKFV HGVRYQCYCY GRGIGEWHCQ
610 620 630 640 650
PLQTYPGTTG PVQVIITETP SQPNSHPIQW NAPEPSHITK YILRWRPKTS
660 670 680 690 700
TGRWKEATIP GHLNSYTIKG LTPGVIYEGQ LISIQQYGHR EVTRFDFTTS
710 720 730 740 750
ASTPVTSNTV TGETAPYSPV VATSESVTEI TASSFVVSWV SASDTVSGFR
760 770 780 790 800
VEYELSEEGD EPQYLDLPST ATSVNIPDLL PGRKYIVNVY QISEEGKQSL
810 820 830 840 850
ILSTSQTTAP DAPPDPTVDQ VDDTSIVVRW SRPQAPITGY RIVYSPSVEG
860 870 880 890 900
SSTELNLPET ANSVTLSDLQ PGVQYNITIY AVEENQESTP VFIQQETTGT
910 920 930 940 950
PRSDNVPPPT DLQFVELTDV KVTIMWTPPD SVVSGYRVEV LPVSLPGEHG
960 970 980 990 1000
QRLPVNRNTF AEITGLSPGV TYLFKVFAVH QGRESNPLTA QQTTKLDAPT
1010 1020 1030 1040 1050
NLQFVNETDR TVLVTWTPPR ARIAGYRLTA GLTRGGQPKQ YNVGPLASKY
1060 1070 1080 1090 1100
PLRNLQPGSE YTVTLVAVKG NQQSPKATGV FTTLQPLRSI PPYNTEVTET
1110 1120 1130 1140 1150
TIVITWTPAP RIGFKLGVRP SQGGEAPREV TSDSGSIVVS GLTPGVEYTY
1160 1170 1180 1190 1200
TIQVLRDGQE RDAPIVNRVV TPLSPPTNLH LEANPDTGVL TVSWERSTTP
1210 1220 1230 1240 1250
DITGYRITTT PTNGQQGTSL EEVVHADQSS CTFENLNPGL EYNVSVYTVK
1260 1270 1280 1290 1300
DDKESAPISD TVVPAVPPPT DLRFTNIGPD TMRVTWAPPP SIELTNLLVR
1310 1320 1330 1340 1350
YSPVKNEEDV AELSISPSDN AVVLTNLLPG TEYLVSVSSV YEQHESIPLR
1360 1370 1380 1390 1400
GRQKTGLDSP TGFDSSDITA NSFTVHWVAP RAPITGYIIR HHAEHSVGRP
1410 1420 1430 1440 1450
RQDRVPPSRN SITLTNLNPG TEYVVSIIAV NGREESPPLI GQQATVSDIP
1460 1470 1480 1490 1500
RDLEVIASTP TSLLISWEPP AVSVRYYRIT YGETGGNSPV QEFTVPGSKS
1510 1520 1530 1540 1550
TATINNIKPG ADYTITLYAV TGRGDSPASS KPVSINYKTE IDKPSQMQVT
1560 1570 1580 1590 1600
DVQDNSISVR WLPSTSPVTG YRVTTTPKNG LGPSKTKTAS PDQTEMTIEG
1610 1620 1630 1640 1650
LQPTVEYVVS VYAQNRNGES QPLVQTAVTT IPAPTNLKFS QVTPTSFTAQ
1660 1670 1680 1690 1700
WIAPSVQLTG YRVRVNPKEK TGPMKEINLS PDSSSVIVSG LMVATKYEVS
1710 1720 1730 1740 1750
VYALKDTLTS RPAQGVITTL ENVSPPRRAR VTDATETTIT ISWRTKTETI
1760 1770 1780 1790 1800
TGFQVDAIPA NGQTPVQRSI SPDVRSYTIT GLQPGTDYKI HLYTLNDNAR
1810 1820 1830 1840 1850
SSPVIIDAST AIDAPSNLRF LTTTPNSLLV SWQAPRARIT GYIIKYEKPG
1860 1870 1880 1890 1900
SPPREVVPRP RPGVTEATIT GLEPGTEYTI YVIALKNNQK SEPLIGRKKT
1910 1920 1930 1940 1950
GQEALSQTTI SWTPFQESSE YIISCQPVGT DEEPLQFQVP GTSTSATLTG
1960 1970 1980 1990 2000
LTRGVTYNII VEALQNQRRH KVREEVVTVG NAVSEGLNQP TDDSCFDPYT
2010 2020 2030 2040 2050
VSHYAIGEEW ERLSDAGFKL TCQCLGFGSG HFRCDSSKWC HDNGVNYKIG
2060 2070 2080 2090 2100
EKWDRQGENG QRMSCTCLGN GKGEFKCDPH EATCYDDGKT YHVGEQWQKE
2110 2120 2130 2140 2150
YLGAICSCTC FGGQRGWRCD NCRRPGAAEP SPDGTTGHTY NQYTQRYNQR
2160 2170
TNTNVNCPIE CFMPLDVQAD RDDSRE
Length:2,176
Mass (Da):239,722
Last modified:March 3, 2009 - v1
Checksum:i52F249E729B49DED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124821 Genomic DNA. No translation available.
BC145271 mRNA. Translation: AAI45272.1.
RefSeqiNP_001263342.1. NM_001276413.1.
UniGeneiMm.193099.

Genome annotation databases

EnsembliENSMUST00000189821; ENSMUSP00000139702; ENSMUSG00000026193.
GeneIDi14268.
UCSCiuc007bka.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124821 Genomic DNA. No translation available.
BC145271 mRNA. Translation: AAI45272.1.
RefSeqiNP_001263342.1. NM_001276413.1.
UniGeneiMm.193099.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiB7ZNJ1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000189821; ENSMUSP00000139702; ENSMUSG00000026193.
GeneIDi14268.
UCSCiuc007bka.2. mouse.

Organism-specific databases

CTDi2335.
MGIiMGI:95566. Fn1.

Phylogenomic databases

GeneTreeiENSGT00830000128240.
HOVERGENiHBG005731.

Miscellaneous databases

ChiTaRSiFn1. mouse.
SOURCEiSearch...

Family and domain databases

Gene3Di2.10.10.10. 2 hits.
2.60.40.10. 15 hits.
InterProiIPR000083. Fibronectin_type1.
IPR003961. FN3_dom.
IPR000562. FN_type2_col-bd.
IPR013783. Ig-like_fold.
IPR013806. Kringle-like.
[Graphical view]
PfamiPF00039. fn1. 12 hits.
PF00040. fn2. 2 hits.
PF00041. fn3. 15 hits.
[Graphical view]
SMARTiSM00058. FN1. 12 hits.
SM00059. FN2. 2 hits.
SM00060. FN3. 15 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 9 hits.
SSF57440. SSF57440. 2 hits.
PROSITEiPS01253. FN1_1. 12 hits.
PS51091. FN1_2. 12 hits.
PS00023. FN2_1. 2 hits.
PS51092. FN2_2. 2 hits.
PS50853. FN3. 14 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
    Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
    J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
    Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
    Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  5. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. Ensembl
    Submitted (SEP-2014) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB7ZNJ1_MOUSE
AccessioniPrimary (citable) accession number: B7ZNJ1
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 6, 2016
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.