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Protein
Submitted name:

Collagen alpha-1(XIV) chain

Gene

Col14a1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • collagen fibril organization Source: MGI
  • homeostasis of number of cells within a tissue Source: MGI
  • regulation of cell growth involved in cardiac muscle cell development Source: MGI
  • ventricular cardiac muscle tissue development Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Collagen alpha-1(XIV) chainImported
Submitted name:
Collagen, type XIV, alpha 1Imported
Submitted name:
Procollagen, type XIV, alpha 1, isoform CRA_aImported
Gene namesi
Name:Col14a1Imported
ORF Names:mCG_11867Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1341272. Col14a1.

Subcellular locationi

GO - Cellular componenti

  • collagen trimer Source: UniProtKB-KW
  • extracellular exosome Source: MGI
  • extracellular space Source: MGI
  • interstitial matrix Source: MGI
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105850.

Family & Domainsi

Keywords - Domaini

CollagenImported

Phylogenomic databases

GeneTreeiENSGT00760000119000.
HOGENOMiHOG000015812.
HOVERGENiHBG051060.
KOiK08133.

Family and domain databases

Gene3Di2.60.40.10. 8 hits.
3.40.50.410. 2 hits.
InterProiIPR008160. Collagen.
IPR013320. ConA-like_dom.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR001791. Laminin_G.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01391. Collagen. 5 hits.
PF00041. fn3. 8 hits.
PF00092. VWA. 2 hits.
[Graphical view]
SMARTiSM00060. FN3. 8 hits.
SM00210. TSPN. 1 hit.
SM00327. VWA. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 6 hits.
SSF49899. SSF49899. 1 hit.
SSF53300. SSF53300. 2 hits.
PROSITEiPS50853. FN3. 8 hits.
PS50234. VWFA. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7ZNH7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMIWQCKMRD WLILAFLAAA CFCTIVRGQV APPTRLRYNV ISHDSIQISW
60 70 80 90 100
KAPRGKFGGY KLLVAPASGG KTNQMNLQNT ATKAIIQGLL PEQNYTVQLI
110 120 130 140 150
AYYKDKESKP AQGQFRIKDL EKRKDPTKPK VKVVDKGNGS KPTSPEEVKF
160 170 180 190 200
FCETPAIADI VILVDGSWSI GRFNFRLVRN FLENLVTAFN VGSEKTRIGL
210 220 230 240 250
AQYSGDPRIE WHLNAFNTKD EVIDAVRSLP YKGGNTLTGL ALNFIFENSF
260 270 280 290 300
KPEAGSRSGV SKIGILITDG KSQDDIIPPS RNLRESGVEL FAIGVKNADL
310 320 330 340 350
SELQEIASEP DSTHVYNVAE FDLMHTVVES LTRTVCSRVE EQDKEIKASA
360 370 380 390 400
LATIGPPTEL ITSEVTARSF MVNWTQSPGK VEKYRVVYYP TRGGKPEEVV
410 420 430 440 450
VDGSVSSTVL KNLMSSTEYQ IAVFAVSAHT ASEGLRGAET TLALPMASDL
460 470 480 490 500
ELYDVTENSM RVRWDAVPGA TGYLILYAPL TEGLAGDEKE MKIGETHTDI
510 520 530 540 550
ELSGLFPNTE YTVTVYAMFG EEASDPATGQ ETTLPLTPPR NLRISNVGSN
560 570 580 590 600
SARLTWDPAS GKISGYRIVY TSADGTEINE VEVDPITTFP LKGLTPLTEY
610 620 630 640 650
SIAIFSIYEE GQSLPLVGEF TTEEVPAQQY LEIDEVKTDS FRVTWHPLSA
660 670 680 690 700
EEGQHKLMWI PVYGGKTQEV DLKEEQDSYV IEGLDPGTEY EVSLLAVLDD
710 720 730 740 750
GSESEVVTAV GTTLDDFWTE APTAIEPTSP VTSVLQTGIR NLVVDDETAT
760 770 780 790 800
SLRVSWDISD SNVEQFRVTY LKAQGDPMEE VVMVPGVQNS LLLKALLPDT
810 820 830 840 850
EYKVTVTPVY TVGEGVSVSA PGKTLPSSGP QNLRVSEEWY NRVRITWDPP
860 870 880 890 900
SGPVKGYRIV YKPVSVPGQT LETFVGADIN TIVMTNLLSG MDYNVKIFAS
910 920 930 940 950
QASGFSDALT GLVQTLFLGV TDLQANQVEM TSLCARWQIH RHATAYRIVL
960 970 980 990 1000
ESLQDTQAQE STVGGGVNRH CFYGLQPDSE YKISVYTKLQ ELEGPSVSIM
1010 1020 1030 1040 1050
QKTQSLPTEP PTFPPTIPPA KEVCKAAKAD LVFMVDGSWS IGDDNFNKII
1060 1070 1080 1090 1100
NFLYSTVGAL DKIGADGTQV AMVQFTDDPR TEFKLDSYKT KETLLDAIRH
1110 1120 1130 1140 1150
ISYKGGNTKT GKAIKHVRDT LFTSDSGTRR GIPKVIVVIT DGRSQDDVNK
1160 1170 1180 1190 1200
ISREMQADGF NIFAIGVADA DYSELVQIGS KPSSRHVFFV DDFDAFKKIE
1210 1220 1230 1240 1250
DELITFVCET ASATCPMVHK DGVDLAGFKM MEMFGLVEKD FSAVEGVSME
1260 1270 1280 1290 1300
PGTFNLFPCY QIHKDALVSQ PTKYLHPEGL PSDYTMSFLF RILPDTPQEP
1310 1320 1330 1340 1350
FALWEILNKN SEPLVGIILD NGGKTLTYFN YDYTGDFQTV TFEGPDIRKM
1360 1370 1380 1390 1400
FYGSFHKLHV VVSKTLAKVV VDCKEVGQKA INASANITSD GVEVLGRMVR
1410 1420 1430 1440 1450
SRGPNGNSAP FQLQMFDIVC STSWASKDRC CELPGLRDEE SCPDLPRSCS
1460 1470 1480 1490 1500
CSETNEVALG PAGPPGGPGL RGPKGQQGEQ GPKGPEGPRG ETGPAGPQGP
1510 1520 1530 1540 1550
PGPQGPSGLS IQGMPGMPGD KGDKGDAGLP GPQGVPGGVG SPGRDGSPGQ
1560 1570 1580 1590 1600
RGFPGKDGSS GPPGPPGPIG IPGAPGVPGI TGSMGPQGAL GPPGVPGAKG
1610 1620 1630 1640 1650
ERGERGDLQS QAMVRAVARQ VCEQLIQSHM ARYTAILNQI PSQSSSIRTI
1660 1670 1680 1690 1700
QGPPGEPGRP GSPGTPGEQG PPGTPGFPGN AGVPGTPGER GLTGVKGEKG
1710 1720 1730 1740 1750
NPGIGTQGPR GPPGPAGPSG ESRPGSPGPP GSPGPRGPPG HLGVPGPQGP
1760 1770 1780 1790
SGQPGYCDPS SCSAYGVGVS HPDQPEFTPV QDEQEAMDLW SAGI
Length:1,794
Mass (Da):192,755
Last modified:March 3, 2009 - v1
Checksum:i745DDA3D24956BD8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC131337 Genomic DNA. No translation available.
AC133156 Genomic DNA. No translation available.
BC138345 mRNA. Translation: AAI38346.1.
BC145244 mRNA. Translation: AAI45245.1.
CH466545 Genomic DNA. Translation: EDL29272.1.
RefSeqiNP_851794.3. NM_181277.3.
UniGeneiMm.297859.

Genome annotation databases

EnsembliENSMUST00000110221; ENSMUSP00000105850; ENSMUSG00000022371.
GeneIDi12818.
KEGGimmu:12818.
UCSCiuc007vsc.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC131337 Genomic DNA. No translation available.
AC133156 Genomic DNA. No translation available.
BC138345 mRNA. Translation: AAI38346.1.
BC145244 mRNA. Translation: AAI45245.1.
CH466545 Genomic DNA. Translation: EDL29272.1.
RefSeqiNP_851794.3. NM_181277.3.
UniGeneiMm.297859.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105850.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000110221; ENSMUSP00000105850; ENSMUSG00000022371.
GeneIDi12818.
KEGGimmu:12818.
UCSCiuc007vsc.2. mouse.

Organism-specific databases

CTDi7373.
MGIiMGI:1341272. Col14a1.

Phylogenomic databases

GeneTreeiENSGT00760000119000.
HOGENOMiHOG000015812.
HOVERGENiHBG051060.
KOiK08133.

Miscellaneous databases

NextBioi282286.
SOURCEiSearch...

Family and domain databases

Gene3Di2.60.40.10. 8 hits.
3.40.50.410. 2 hits.
InterProiIPR008160. Collagen.
IPR013320. ConA-like_dom.
IPR003961. FN3_dom.
IPR013783. Ig-like_fold.
IPR001791. Laminin_G.
IPR002035. VWF_A.
[Graphical view]
PfamiPF01391. Collagen. 5 hits.
PF00041. fn3. 8 hits.
PF00092. VWA. 2 hits.
[Graphical view]
SMARTiSM00060. FN3. 8 hits.
SM00210. TSPN. 1 hit.
SM00327. VWA. 2 hits.
[Graphical view]
SUPFAMiSSF49265. SSF49265. 6 hits.
SSF49899. SSF49899. 1 hit.
SSF53300. SSF53300. 2 hits.
PROSITEiPS50853. FN3. 8 hits.
PS50234. VWFA. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: BrainImported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  6. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB7ZNH7_MOUSE
AccessioniPrimary (citable) accession number: B7ZNH7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 24, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.