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Protein
Submitted name:

LPP protein

Gene

LPP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-bindingSAAS annotation, ZincSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
LPP proteinImported
Gene namesi
Name:LPPImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30440.

PTM / Processingi

Proteomic databases

PaxDbiB7ZLW0.
PeptideAtlasiB7ZLW0.
PRIDEiB7ZLW0.

Expressioni

Gene expression databases

GenevisibleiB7ZLW0. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000318089.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini414 – 473LIM zinc-bindingInterPro annotationAdd BLAST60
Domaini474 – 534LIM zinc-bindingInterPro annotationAdd BLAST61
Domaini535 – 603LIM zinc-bindingInterPro annotationAdd BLAST69

Phylogenomic databases

eggNOGiKOG1701. Eukaryota.
ENOG410Y3GP. LUCA.
HOVERGENiHBG093602.
KOiK16676.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiView protein in InterPro
IPR028771. LPP.
IPR001781. Znf_LIM.
PANTHERiPTHR24207:SF5. PTHR24207:SF5. 1 hit.
PfamiView protein in Pfam
PF00412. LIM. 3 hits.
SMARTiView protein in SMART
SM00132. LIM. 3 hits.
PROSITEiView protein in PROSITE
PS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.

Sequencei

Sequence statusi: Complete.

B7ZLW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHPSWLPPK STGEPLGHVP ARMETTHSFG NPSISVSTQQ PPKKFAPVVA
60 70 80 90 100
PKPKYNPYKQ PGGEGDFLPP PPPPLDDSSA LPSISGNFPP PPPLDEEVFK
110 120 130 140 150
VQGNPGGKTL EERRSSLDAE IDSLTSILAD LECSSPYKPR PPQSSTGSTA
160 170 180 190 200
SPPVSTPVTG HKRMVIPNQP PLTATKKSTL KPQPAPQAGP IPVAPIGTLK
210 220 230 240 250
PQPQPVPASY TTASTSSRPT FNVQVKSAQP SPHYMAAPSS GQIYGSGPQG
260 270 280 290 300
YNTQPVPVSG QCPPPSTRGG MDYAYIPPPG LQPEPGYGYA PNQGRYYEGY
310 320 330 340 350
YAAGPGYGGR NDSDPTYGQQ GHPNTWKREP GYTPPGAGNQ NPPGMYPVTG
360 370 380 390 400
PKKTYITDPV SAPCAPPLQP KGGHSGQLGP SSVAPSFRPE DELEHLTKKM
410 420 430 440 450
LYDMENPPAD EYFGRCARCG ENVVGEGTGC TAMDQVFHVD CFTCIICNNK
460 470 480 490 500
LRGQPFYAVE KKAYCEPCYI NTLEQCNVCS KPIMERILRA TGKAYHPHCF
510 520 530 540 550
TCVMCHRSLD GIPFTVDAGG LIHCIEDFHK KFAPRCSVCK EPIMPAPGQE
560 570 580 590 600
ETVRIVALDR DFHVHCYRCE DCGGLLSEGD NQGCYPLDGH ILCKTCNSAR
610
IRVLTAKAST DL
Length:612
Mass (Da):65,774
Last modified:March 3, 2009 - v1
Checksum:i439CE51A96CE4DDD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC144076 mRNA. Translation: AAI44077.1.
RefSeqiNP_001161143.1. NM_001167671.2.
UniGeneiHs.720220.

Genome annotation databases

GeneIDi4026.
KEGGihsa:4026.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC144076 mRNA. Translation: AAI44077.1.
RefSeqiNP_001161143.1. NM_001167671.2.
UniGeneiHs.720220.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000318089.

Proteomic databases

PaxDbiB7ZLW0.
PeptideAtlasiB7ZLW0.
PRIDEiB7ZLW0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4026.
KEGGihsa:4026.

Organism-specific databases

CTDi4026.
PharmGKBiPA30440.

Phylogenomic databases

eggNOGiKOG1701. Eukaryota.
ENOG410Y3GP. LUCA.
HOVERGENiHBG093602.
KOiK16676.

Miscellaneous databases

ChiTaRSiLPP. human.
GenomeRNAii4026.

Gene expression databases

GenevisibleiB7ZLW0. HS.

Family and domain databases

Gene3Di2.10.110.10. 3 hits.
InterProiView protein in InterPro
IPR028771. LPP.
IPR001781. Znf_LIM.
PANTHERiPTHR24207:SF5. PTHR24207:SF5. 1 hit.
PfamiView protein in Pfam
PF00412. LIM. 3 hits.
SMARTiView protein in SMART
SM00132. LIM. 3 hits.
PROSITEiView protein in PROSITE
PS00478. LIM_DOMAIN_1. 2 hits.
PS50023. LIM_DOMAIN_2. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiB7ZLW0_HUMAN
AccessioniPrimary (citable) accession number: B7ZLW0
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: February 15, 2017
This is version 47 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.