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B7ZBV9

- B7ZBV9_MOUSE

UniProt

B7ZBV9 - B7ZBV9_MOUSE

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Protein
Submitted name: Potassium voltage-gated channel subfamily KQT member 2
Gene
Kcnq2, mCG_23080
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. delayed rectifier potassium channel activity Source: RefGenome

GO - Biological processi

  1. transmission of nerve impulse Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ion channel, Potassium channelSAAS annotations

Keywords - Biological processi

Ion transport, Potassium transport, Transport

Keywords - Ligandi

Potassium

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel subfamily KQT member 2Imported
Submitted name:
Potassium voltage-gated channel, subfamily Q, member 2, isoform CRA_hImported
Gene namesi
Name:Kcnq2Imported
ORF Names:mCG_23080Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 2

Organism-specific databases

MGIiMGI:1309503. Kcnq2.

Subcellular locationi

GO - Cellular componenti

  1. voltage-gated potassium channel complex Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00550000074513.
HOGENOMiHOG000220839.
HOVERGENiHBG059014.
KOiK04927.
OMAiSSMGQKN.
OrthoDBiEOG73804Z.
TreeFamiTF315186.

Family and domain databases

InterProiIPR020969. Ankyrin-G_BS.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR003937. K_chnl_volt-dep_KCNQ.
IPR003947. K_chnl_volt-dep_KCNQ2.
IPR013821. K_chnl_volt-dep_KCNQ_C.
IPR028325. VG_K_chnl.
[Graphical view]
PANTHERiPTHR11537. PTHR11537. 1 hit.
PfamiPF00520. Ion_trans. 1 hit.
PF03520. KCNQ_channel. 1 hit.
PF11956. KCNQC3-Ank-G_bd. 1 hit.
[Graphical view]
PRINTSiPR00169. KCHANNEL.
PR01461. KCNQ2CHANNEL.
PR01459. KCNQCHANNEL.

Sequencei

Sequence statusi: Complete.

B7ZBV9-1 [UniParc]FASTAAdd to Basket

« Hide

MVQKSRNGGV YPGTSGEKKL KVGFVGLDPG APDSTRDGAL LIAGSEAPKR    50
GSVLSKPRTG GAGAGKPPKR NAFYRKLQNF LYNVLERPRG WAFIYHAYVF 100
LLVFSCLVLS VFSTIKEYEK SSEGALYILE IVTIVVFGVE YFVRIWAAGC 150
CCRYRGWRGR LKFARKPFCV IDIMVLIASI AVLAAGSQGN VFATSALRSL 200
RFLQILRMIR MDRRGGTWKL LGSVVYAHSK ELVTAWYIGF LCLILASFLV 250
YLAEKGENDH FDTYADALWW GLITLTTIGY GDKYPQTWNG RLLAATFTLI 300
GVSFFALPAG ILGSGFALKV QEQHRQKHFE KRRNPAAGLI QSAWRFYATN 350
LSRTDLHSTW QYYERTVTVP MYSSQTQTYG ASRLIPPLNQ LELLRNLKSK 400
SGLTFRKEPQ PEPSPSKGRP CRGCLCGCCP GHSSQKVSLK DRVFSSPRGM 450
AAKGKGSPQA QTVRRSPSAD QSLDDSPSKV PKSWSFGDRS RTRQAFRIKG 500
AASRQNSEEA SLPGEDIVED NKSCNCEFVT EDLTPGLKVS IRAVCVMRFL 550
VSKRKFKESL RPYDVMDVIE QYSAGHLDML SRIKSLQSRV DQIVGRGPTI 600
TDKDRTKGPA ETELPEDPSM MGRLGKVEKQ VLSMEKKLDF LVSIYTQRMG 650
IPPAETEAYF GAKEPEPAPP YHSPEDSRDH ADKHGCIIKI VRSTSSTGQR 700
NYAAPPAIPP AQCPPSTSWQ QSHQRHGTSP VGDHGSLVRI PPPPAHERSL 750
SAYGGGNRAS TEFLRLEGTP ACRPSEAALR DSDTSISIPS VDHEELERSF 800
SGFSISQSKE NLDALGSCYA AVAPCAKVRP YIAEGESDTD SDLCTPCGPP 850
PRSATGEGPF GDVAWAGPRK 870
Length:870
Mass (Da):95,742
Last modified:March 3, 2009 - v1
Checksum:i9C6106C27CE70C5F
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei870 – 8701Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL450341 Genomic DNA. No translation available.
CH466626 Genomic DNA. Translation: EDL07381.1.
RefSeqiNP_034741.2. NM_010611.2.
UniGeneiMm.40615.
Mm.440175.

Genome annotation databases

EnsembliENSMUST00000149964; ENSMUSP00000122915; ENSMUSG00000016346.
GeneIDi16536.
KEGGimmu:16536.
UCSCiuc008okz.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL450341 Genomic DNA. No translation available.
CH466626 Genomic DNA. Translation: EDL07381.1 .
RefSeqi NP_034741.2. NM_010611.2.
UniGenei Mm.40615.
Mm.440175.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 16536.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000149964 ; ENSMUSP00000122915 ; ENSMUSG00000016346 .
GeneIDi 16536.
KEGGi mmu:16536.
UCSCi uc008okz.1. mouse.

Organism-specific databases

CTDi 3785.
MGIi MGI:1309503. Kcnq2.

Phylogenomic databases

GeneTreei ENSGT00550000074513.
HOGENOMi HOG000220839.
HOVERGENi HBG059014.
KOi K04927.
OMAi SSMGQKN.
OrthoDBi EOG73804Z.
TreeFami TF315186.

Miscellaneous databases

NextBioi 289965.
SOURCEi Search...

Family and domain databases

InterProi IPR020969. Ankyrin-G_BS.
IPR005821. Ion_trans_dom.
IPR003091. K_chnl.
IPR003937. K_chnl_volt-dep_KCNQ.
IPR003947. K_chnl_volt-dep_KCNQ2.
IPR013821. K_chnl_volt-dep_KCNQ_C.
IPR028325. VG_K_chnl.
[Graphical view ]
PANTHERi PTHR11537. PTHR11537. 1 hit.
Pfami PF00520. Ion_trans. 1 hit.
PF03520. KCNQ_channel. 1 hit.
PF11956. KCNQC3-Ank-G_bd. 1 hit.
[Graphical view ]
PRINTSi PR00169. KCHANNEL.
PR01461. KCNQ2CHANNEL.
PR01459. KCNQCHANNEL.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
    Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
    Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiB7ZBV9_MOUSE
AccessioniPrimary (citable) accession number: B7ZBV9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 14, 2014
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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