Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B7ZBV6

- B7ZBV6_MOUSE

UniProt

B7ZBV6 - B7ZBV6_MOUSE

Protein
Submitted name:

Potassium voltage-gated channel subfamily KQT member 2

Gene

Kcnq2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 42 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. delayed rectifier potassium channel activity Source: RefGenome

    GO - Biological processi

    1. transmission of nerve impulse Source: MGI

    Keywords - Molecular functioni

    Ion channel, Potassium channelSAAS annotation

    Keywords - Biological processi

    Ion transport, Potassium transport, Transport

    Keywords - Ligandi

    Potassium

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Potassium voltage-gated channel subfamily KQT member 2Imported
    Gene namesi
    Name:Kcnq2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:1309503. Kcnq2.

    Subcellular locationi

    GO - Cellular componenti

    1. voltage-gated potassium channel complex Source: InterPro

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiB7ZBV6.

    Structurei

    3D structure databases

    ProteinModelPortaliB7ZBV6.
    SMRiB7ZBV6. Positions 65-391.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00550000074513.
    HOVERGENiHBG059014.
    KOiK04927.

    Family and domain databases

    InterProiIPR005821. Ion_trans_dom.
    IPR003091. K_chnl.
    IPR003937. K_chnl_volt-dep_KCNQ.
    IPR003947. K_chnl_volt-dep_KCNQ2.
    IPR013821. K_chnl_volt-dep_KCNQ_C.
    IPR028325. VG_K_chnl.
    [Graphical view]
    PANTHERiPTHR11537. PTHR11537. 1 hit.
    PfamiPF00520. Ion_trans. 1 hit.
    PF03520. KCNQ_channel. 2 hits.
    [Graphical view]
    PRINTSiPR00169. KCHANNEL.
    PR01461. KCNQ2CHANNEL.
    PR01459. KCNQCHANNEL.

    Sequencei

    Sequence statusi: Complete.

    B7ZBV6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MVQKSRNGGV YPGTSGEKKL KVGFVGLDPG APDSTRDGAL LIAGSEAPKR    50
    GSVLSKPRTG GAGAGKPPKR NAFYRKLQNF LYNVLERPRG WAFIYHAYVF 100
    LLVFSCLVLS VFSTIKEYEK SSEGALYILE IVTIVVFGVE YFVRIWAAGC 150
    CCRYRGWRGR LKFARKPFCV IDIMVLIASI AVLAAGSQGN VFATSALRSL 200
    RFLQILRMIR MDRRGGTWKL LGSVVYAHSK ELVTAWYIGF LCLILASFLV 250
    YLAEKGENDH FDTYADALWW GLITLTTIGY GDKYPQTWNG RLLAATFTLI 300
    GVSFFALPAG ILGSGFALKV QEQHRQKHFE KRRNPAAGLI QSAWRFYATN 350
    LSRTDLHSTW QYYERTVTVP MYRLIPPLNQ LELLRNLKSK SGLTFRKEPQ 400
    PEPSPSQKVS LKDRVFSSPR GMAAKGKGSP QAQTVRRSPS ADQSLDDSPS 450
    KVPKSWSFGD RSRTRQAFRI KGAASRQNSE EASLPGEDIV EDNKSCNCEF 500
    VTEDLTPGLK VSIRAVCVMR FLVSKRKFKE SLRPYDVMDV IEQYSAGHLD 550
    MLSRIKSLQS RQEPLPVQSG HEQGPPGQNQ AWHKGHQGLG DRVDQIVGRG 600
    PTITDKDRTK GPAETELPED PSMMGRLGKV EKQVLSMEKK LDFLVSIYTQ 650
    RMGIPPAETE AYFGAKEPEP APPYHSPEDS RDHADKHGCI IKIVRSTSST 700
    GQRNYAAPPA IPPAQCPPST SWQQSHQRHG TSPVGDHGSL VLRLERSAGM 750
    MSCH 754
    Length:754
    Mass (Da):83,893
    Last modified:March 3, 2009 - v1
    Checksum:i1A1864896B50660E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL450341 Genomic DNA. No translation available.
    RefSeqiNP_001003825.1. NM_001003825.2.
    UniGeneiMm.40615.
    Mm.440175.

    Genome annotation databases

    EnsembliENSMUST00000049792; ENSMUSP00000052453; ENSMUSG00000016346.
    GeneIDi16536.
    KEGGimmu:16536.
    UCSCiuc008oku.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL450341 Genomic DNA. No translation available.
    RefSeqi NP_001003825.1. NM_001003825.2.
    UniGenei Mm.40615.
    Mm.440175.

    3D structure databases

    ProteinModelPortali B7ZBV6.
    SMRi B7ZBV6. Positions 65-391.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    DNASUi 16536.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000049792 ; ENSMUSP00000052453 ; ENSMUSG00000016346 .
    GeneIDi 16536.
    KEGGi mmu:16536.
    UCSCi uc008oku.1. mouse.

    Organism-specific databases

    CTDi 3785.
    MGIi MGI:1309503. Kcnq2.

    Phylogenomic databases

    GeneTreei ENSGT00550000074513.
    HOVERGENi HBG059014.
    KOi K04927.

    Miscellaneous databases

    NextBioi 289965.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi B7ZBV6.

    Family and domain databases

    InterProi IPR005821. Ion_trans_dom.
    IPR003091. K_chnl.
    IPR003937. K_chnl_volt-dep_KCNQ.
    IPR003947. K_chnl_volt-dep_KCNQ2.
    IPR013821. K_chnl_volt-dep_KCNQ_C.
    IPR028325. VG_K_chnl.
    [Graphical view ]
    PANTHERi PTHR11537. PTHR11537. 1 hit.
    Pfami PF00520. Ion_trans. 1 hit.
    PF03520. KCNQ_channel. 2 hits.
    [Graphical view ]
    PRINTSi PR00169. KCHANNEL.
    PR01461. KCNQ2CHANNEL.
    PR01459. KCNQCHANNEL.
    ProtoNeti Search...

    Publicationsi

    1. "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L.
      Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiB7ZBV6_MOUSE
    AccessioniPrimary (citable) accession number: B7ZBV6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 42 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3