B7ZBV5 (B7ZBV5_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Potassium voltage-gated channel subfamily KQT member 2 Ensembl ENSMUSP00000080243

Gene names

Name:

Kcnq2 Ensembl ENSMUSP00000080243 MGI 1309503

Organism

Mus musculus (Mouse) [Reference proteome] Ensembl ENSMUSP00000080243

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	570 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data. Ensembl ENSMUSP00000080243

Ontologies

Keywords
Biological process	Ion transport Potassium transport Transport
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS003091
Ligand	Potassium
Molecular function	Ion channel Potassium channel SAAS SAAS003091
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	transmission of nerve impulse Inferred from mutant phenotype PubMed 10854243. Source: MGI
Cellular_component	voltage-gated potassium channel complex Inferred from electronic annotation. Source: InterPro
Molecular_function	delayed rectifier potassium channel activity Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7ZBV5 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 6BEDA2952C1C7178	FASTA	570	63,836
	10 20 30 40 50 60 MVQKSRNGGV YPGTSGEKKL KVGFVGLDPG APDSTRDGAL LIAGSEAPKR GSVLSKPRTG 70 80 90 100 110 120 GAGAGKPPKR NAFYRKLQNF LYNVLERPRG WAFIYHAYVF LLVFSCLVLS VFSTIKEYEK 130 140 150 160 170 180 SSEGALYILE IVTIVVFGVE YFVRIWAAGC CCRYRGWRGR LKFARKPFCV IDIMVLIASI 190 200 210 220 230 240 AVLAAGSQGN VFATSALRSL RFLQILRMIR MDRRGGTWKL LGSVVYAHSK ELVTAWYIGF 250 260 270 280 290 300 LCLILASFLV YLAEKGENDH FDTYADALWW GLITLTTIGY GDKYPQTWNG RLLAATFTLI 310 320 330 340 350 360 GVSFFALPAG ILGSGFALKV QEQHRQKHFE KRRNPAAGLI QSAWRFYATN LSRTDLHSTW 370 380 390 400 410 420 QYYERTVTVP MYRLIPPLNQ LELLRNLKSK SGLTFRKEPQ PEPSPSQKVS LKDRVFSSPR 430 440 450 460 470 480 GMAAKGKGSP QAQTVRRSPS ADQSLDDSPS KVPKSWSFGD RSRTRQAFRI KGAASRQNSE 490 500 510 520 530 540 EASLPGEDIV EDNKSCNCEF VTEDLTPGLK VSIRAVCVMR FLVSKRKFKE SLRPYDVMDV 550 560 570 IEQYSAGHLD MLSRIKSLQS RSCDWRGVLA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000080243.
[2]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000080243.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL450341 Genomic DNA. No translation available.
IPI	IPI00229675.
RefSeq	NP_001006675.1. NM_001006674.1.
UniGene	Mm.40615. Mm.440175.
3D structure databases
ProteinModelPortal	B7ZBV5.
SMR	B7ZBV5. Positions 65-316, 503-528.
ModBase	Search...
Protocols and materials databases
DNASU	16536.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000081528; ENSMUSP00000080243; ENSMUSG00000016346.
GeneID	16536.
KEGG	mmu:16536.
UCSC	uc008okv.1. mouse.
Organism-specific databases
CTD	3785.
MGI	MGI:1309503. Kcnq2.
Phylogenomic databases
GeneTree	ENSGT00550000074513.
HOVERGEN	HBG059014.
KO	K04927.
Gene expression databases
ArrayExpress	B7ZBV5.
Family and domain databases
InterPro	IPR005821. Ion_trans_dom. IPR003091. K_chnl. IPR003937. K_chnl_volt-dep_KCNQ. IPR003947. K_chnl_volt-dep_KCNQ2. IPR013821. K_chnl_volt-dep_KCNQ_C. [Graphical view]
PANTHER	PTHR11537. PTHR11537. 1 hit.
Pfam	PF00520. Ion_trans. 1 hit. PF03520. KCNQ_channel. 1 hit. [Graphical view]
PRINTS	PR00169. KCHANNEL. PR01461. KCNQ2CHANNEL. PR01459. KCNQCHANNEL.
ProtoNet	Search...
Other
NextBio	289965.
SOURCE	Search...

Entry information

Entry name

B7ZBV5_MOUSE

Accession

Primary (citable) accession number: B7ZBV5

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)