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B7ZB79

- B7ZB79_HUMAN

UniProt

B7ZB79 - B7ZB79_HUMAN

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Protein
Submitted name: cDNA, FLJ79443, highly similar to Frizzled-6
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB-KW
  2. Wnt-activated receptor activity Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. Wnt signaling pathway, planar cell polarity pathway Source: Ensembl
  2. cell proliferation in midbrain Source: Ensembl
  3. establishment of planar polarity Source: Ensembl
  4. hair follicle development Source: Ensembl
  5. inner ear morphogenesis Source: Ensembl
  6. neural tube closure Source: Ensembl
  7. platelet activation Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinSAAS annotations, ReceptorSAAS annotations

Keywords - Biological processi

Wnt signaling pathwaySAAS annotations

Protein family/group databases

MEROPSiI93.001.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA, FLJ79443, highly similar to Frizzled-6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. apical part of cell Source: Ensembl
  2. apicolateral plasma membrane Source: Ensembl
  3. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotations

Expressioni

Gene expression databases

ArrayExpressiB7ZB79.
BgeeiB7ZB79.

Family & Domainsi

Sequence similaritiesi

Contains FZ (frizzled) domain.SAAS annotations

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

HOVERGENiHBG006977.

Family and domain databases

Gene3Di1.10.2000.10. 1 hit.
InterProiIPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view]
PANTHERiPTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
PfamiPF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view]
PRINTSiPR00489. FRIZZLED.
SMARTiSM00063. FRI. 1 hit.
[Graphical view]
SUPFAMiSSF63501. SSF63501. 1 hit.
PROSITEiPS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7ZB79-1 [UniParc]FASTAAdd to Basket

« Hide

MAYNMTFFPN LMGHYDQSIA AVEMEHFLPL ANLECSPNIE TFLCKAFVPT    50
CIEQIHVVPP CRKLCEKVYS DCKKLIDTFG IRWPEELECD RLQYCDETVP 100
VTFDPHTEFL GPQKKTEQVQ RDIGFWCPRH LKTSGGQGYK FLGIDQCAPP 150
CPNMYFKSDE LEFAKSFIGT VSIFCLCATL FTFLTFLIDV RRFRYPERPI 200
IYYSVCYSIV SLMYFIGFLL GDSTACNKAD EKLELGDTVV LGSQNKACTV 250
LFMLLYFFTM AGTVWWVILT ITWFLAAGRK WSCEAIEQKA VWFHAVAWGT 300
PGFLTVMLLA MNKVEGDNIS GVCFVGLYDL DASRYFVLLP LCLCVFVGLS 350
LLLAGIISLN HVRQVIQHDG RNQEKLKKFM IRIGVFSGLY LVPLVTLLGC 400
YVYEQVNRIT WEITWVSDHC RQYHIPCPYQ AKAKARPELA LFMIKYLMTL 450
IVGISAVFWV GSKKTCTEWA GFFKRNRKRD PISESRRVLQ ESCEFFLKHN 500
SKVKHKKKHY KPSSHKLKVI SKSMGTSTGA TANHGTSAVA ITSHDYLGQE 550
TLTEIQTSPE TSMREVKADG ASTPRLREQD CGEPASPAAS ISRLSGEQVD 600
GKGQAGSVSE SARSEGRISP KSDITDTGLA QSNNLQVPSS SEPSSLKGST 650
SLLVHPVSGV RKEQGGGCHS DT 672
Length:672
Mass (Da):75,320
Last modified:March 3, 2009 - v1
Checksum:iEBF580CD955A9864
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK316544 mRNA. Translation: BAH14915.1.
UniGeneiHs.591863.
Hs.676099.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK316544 mRNA. Translation: BAH14915.1 .
UniGenei Hs.591863.
Hs.676099.

3D structure databases

ModBasei Search...

Protein family/group databases

MEROPSi I93.001.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG006977.

Miscellaneous databases

NextBioi 35481005.

Gene expression databases

ArrayExpressi B7ZB79.
Bgeei B7ZB79.

Family and domain databases

Gene3Di 1.10.2000.10. 1 hit.
InterProi IPR000539. Frizzled.
IPR015526. Frizzled/SFRP.
IPR020067. Frizzled_dom.
IPR026543. FZD6.
IPR017981. GPCR_2-like.
[Graphical view ]
PANTHERi PTHR11309. PTHR11309. 1 hit.
PTHR11309:SF75. PTHR11309:SF75. 1 hit.
Pfami PF01534. Frizzled. 1 hit.
PF01392. Fz. 1 hit.
[Graphical view ]
PRINTSi PR00489. FRIZZLED.
SMARTi SM00063. FRI. 1 hit.
[Graphical view ]
SUPFAMi SSF63501. SSF63501. 1 hit.
PROSITEi PS50038. FZ. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: UterusImported.

Entry informationi

Entry nameiB7ZB79_HUMAN
AccessioniPrimary (citable) accession number: B7ZB79
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 3, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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