Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B7ZB79

- B7ZB79_HUMAN

UniProt

B7ZB79 - B7ZB79_HUMAN

Protein
Submitted name:

cDNA, FLJ79443, highly similar to Frizzled-6

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 39 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. Wnt-activated receptor activity Source: InterPro

    GO - Biological processi

    1. cell proliferation in midbrain Source: Ensembl
    2. establishment of planar polarity Source: Ensembl
    3. hair follicle development Source: Ensembl
    4. inner ear morphogenesis Source: Ensembl
    5. neural tube closure Source: Ensembl
    6. platelet activation Source: Ensembl
    7. Wnt signaling pathway, planar cell polarity pathway Source: Ensembl

    Keywords - Molecular functioni

    Developmental proteinSAAS annotation, ReceptorSAAS annotation

    Keywords - Biological processi

    Wnt signaling pathwaySAAS annotation

    Protein family/group databases

    MEROPSiI93.001.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA, FLJ79443, highly similar to Frizzled-6Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. apical part of cell Source: Ensembl
    2. apicolateral plasma membrane Source: Ensembl
    3. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    ArrayExpressiB7ZB79.
    BgeeiB7ZB79.

    Family & Domainsi

    Sequence similaritiesi

    Contains FZ (frizzled) domain.SAAS annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG006977.

    Family and domain databases

    Gene3Di1.10.2000.10. 1 hit.
    InterProiIPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026543. FZD6.
    IPR017981. GPCR_2-like.
    [Graphical view]
    PANTHERiPTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    PfamiPF01534. Frizzled. 1 hit.
    PF01392. Fz. 1 hit.
    [Graphical view]
    PRINTSiPR00489. FRIZZLED.
    SMARTiSM00063. FRI. 1 hit.
    [Graphical view]
    SUPFAMiSSF63501. SSF63501. 1 hit.
    PROSITEiPS50038. FZ. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7ZB79-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAYNMTFFPN LMGHYDQSIA AVEMEHFLPL ANLECSPNIE TFLCKAFVPT    50
    CIEQIHVVPP CRKLCEKVYS DCKKLIDTFG IRWPEELECD RLQYCDETVP 100
    VTFDPHTEFL GPQKKTEQVQ RDIGFWCPRH LKTSGGQGYK FLGIDQCAPP 150
    CPNMYFKSDE LEFAKSFIGT VSIFCLCATL FTFLTFLIDV RRFRYPERPI 200
    IYYSVCYSIV SLMYFIGFLL GDSTACNKAD EKLELGDTVV LGSQNKACTV 250
    LFMLLYFFTM AGTVWWVILT ITWFLAAGRK WSCEAIEQKA VWFHAVAWGT 300
    PGFLTVMLLA MNKVEGDNIS GVCFVGLYDL DASRYFVLLP LCLCVFVGLS 350
    LLLAGIISLN HVRQVIQHDG RNQEKLKKFM IRIGVFSGLY LVPLVTLLGC 400
    YVYEQVNRIT WEITWVSDHC RQYHIPCPYQ AKAKARPELA LFMIKYLMTL 450
    IVGISAVFWV GSKKTCTEWA GFFKRNRKRD PISESRRVLQ ESCEFFLKHN 500
    SKVKHKKKHY KPSSHKLKVI SKSMGTSTGA TANHGTSAVA ITSHDYLGQE 550
    TLTEIQTSPE TSMREVKADG ASTPRLREQD CGEPASPAAS ISRLSGEQVD 600
    GKGQAGSVSE SARSEGRISP KSDITDTGLA QSNNLQVPSS SEPSSLKGST 650
    SLLVHPVSGV RKEQGGGCHS DT 672
    Length:672
    Mass (Da):75,320
    Last modified:March 3, 2009 - v1
    Checksum:iEBF580CD955A9864
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK316544 mRNA. Translation: BAH14915.1.
    UniGeneiHs.591863.
    Hs.676099.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK316544 mRNA. Translation: BAH14915.1 .
    UniGenei Hs.591863.
    Hs.676099.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein family/group databases

    MEROPSi I93.001.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG006977.

    Miscellaneous databases

    NextBioi 35481005.

    Gene expression databases

    ArrayExpressi B7ZB79.
    Bgeei B7ZB79.

    Family and domain databases

    Gene3Di 1.10.2000.10. 1 hit.
    InterProi IPR000539. Frizzled.
    IPR015526. Frizzled/SFRP.
    IPR020067. Frizzled_dom.
    IPR026543. FZD6.
    IPR017981. GPCR_2-like.
    [Graphical view ]
    PANTHERi PTHR11309. PTHR11309. 1 hit.
    PTHR11309:SF75. PTHR11309:SF75. 1 hit.
    Pfami PF01534. Frizzled. 1 hit.
    PF01392. Fz. 1 hit.
    [Graphical view ]
    PRINTSi PR00489. FRIZZLED.
    SMARTi SM00063. FRI. 1 hit.
    [Graphical view ]
    SUPFAMi SSF63501. SSF63501. 1 hit.
    PROSITEi PS50038. FZ. 1 hit.
    PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: UterusImported.

    Entry informationi

    Entry nameiB7ZB79_HUMAN
    AccessioniPrimary (citable) accession number: B7ZB79
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 39 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.