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Protein
Submitted name:

Ribose-phosphate pyrophosphokinase 1

Gene

PRPS1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Ribose-phosphate pyrophosphokinase 1Imported
Submitted name:
cDNA, FLJ79366, highly similar to Ribose-phosphate pyrophosphokinase I (EC 2.7.6.1)Imported
Gene namesi
Name:PRPS1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome X

Organism-specific databases

HGNCiHGNC:9462. PRPS1.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000147224.

PTM / Processingi

Proteomic databases

PeptideAtlasiB7ZB02.
PRIDEiB7ZB02.

Expressioni

Gene expression databases

BgeeiENSG00000147224.
ExpressionAtlasiB7ZB02. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000361512.

Structurei

3D structure databases

ProteinModelPortaliB7ZB02.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiKOG1448. Eukaryota.
COG0462. LUCA.
GeneTreeiENSGT00550000074583.
HOVERGENiHBG106516.

Family and domain databases

CDDicd06223. PRTases_typeI. 1 hit.
Gene3Di3.40.50.2020. 1 hit.
InterProiIPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamiPF14572. Pribosyl_synth. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01251. ribP_PPkin. 1 hit.

Sequencei

Sequence statusi: Complete.

B7ZB02-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLVGDVKDR VAILVDDMAD TCGTICHAAD KLLSAGATRV YAILTHGIFS
60 70 80 90 100
GPAISRINNA CFEAVVVTNT IPQEDKMKHC SKIQVIDISM ILAEAIRRTH
110
NGESVSYLFS HVPL
Length:114
Mass (Da):12,324
Last modified:March 3, 2009 - v1
Checksum:iA2BA69EDAB8EF6B9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137787 Genomic DNA. No translation available.
AL772400 Genomic DNA. No translation available.
AK316467 mRNA. Translation: BAH14838.1.
RefSeqiNP_001191331.1. NM_001204402.1.
UniGeneiHs.56.

Genome annotation databases

EnsembliENST00000372428; ENSP00000361505; ENSG00000147224.
GeneIDi5631.
UCSCiuc011msj.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137787 Genomic DNA. No translation available.
AL772400 Genomic DNA. No translation available.
AK316467 mRNA. Translation: BAH14838.1.
RefSeqiNP_001191331.1. NM_001204402.1.
UniGeneiHs.56.

3D structure databases

ProteinModelPortaliB7ZB02.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000361512.

Proteomic databases

PeptideAtlasiB7ZB02.
PRIDEiB7ZB02.

Protocols and materials databases

DNASUi5631.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000372428; ENSP00000361505; ENSG00000147224.
GeneIDi5631.
UCSCiuc011msj.2. human.

Organism-specific databases

CTDi5631.
HGNCiHGNC:9462. PRPS1.
OpenTargetsiENSG00000147224.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG1448. Eukaryota.
COG0462. LUCA.
GeneTreeiENSGT00550000074583.
HOVERGENiHBG106516.

Miscellaneous databases

GenomeRNAii5631.

Gene expression databases

BgeeiENSG00000147224.
ExpressionAtlasiB7ZB02. baseline and differential.

Family and domain databases

CDDicd06223. PRTases_typeI. 1 hit.
Gene3Di3.40.50.2020. 1 hit.
InterProiIPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
IPR005946. Rib-P_diPkinase.
[Graphical view]
PfamiPF14572. Pribosyl_synth. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01251. ribP_PPkin. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB7ZB02_HUMAN
AccessioniPrimary (citable) accession number: B7ZB02
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 2, 2016
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.