B7ZAP5 (B7ZAP5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hepatocyte nuclear factor 3-alpha Ensembl ENSP00000440178

Submitted name:
cDNA, FLJ79259, highly similar to Hepatocyte nuclear factor 3-alpha EMBL BAH14731.1

Gene names

Name:

FOXA1 Ensembl ENSP00000440178

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAH14731.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	439 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 fork-head DNA-binding domain. SAAS SAAS018122

Ontologies

Keywords
Ligand	DNA-binding SAAS SAAS018122
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	chromatin remodeling Inferred from electronic annotation. Source: Compara epithelial cell maturation involved in prostate gland development Inferred from electronic annotation. Source: Compara epithelial tube branching involved in lung morphogenesis Inferred from electronic annotation. Source: Compara epithelial-mesenchymal signaling involved in prostate gland development Inferred from electronic annotation. Source: Compara glucose homeostasis Inferred from electronic annotation. Source: Compara hormone metabolic process Inferred from electronic annotation. Source: Compara lung epithelial cell differentiation Inferred from electronic annotation. Source: Compara neuron fate specification Inferred from electronic annotation. Source: Compara positive regulation of neuron differentiation Inferred from electronic annotation. Source: Compara positive regulation of transcription from RNA polymerase II promoter Inferred from electronic annotation. Source: Compara prostate gland epithelium morphogenesis Inferred from electronic annotation. Source: Compara prostate gland stromal morphogenesis Inferred from electronic annotation. Source: Compara secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development Inferred from electronic annotation. Source: Compara
Cellular_component	nucleus Inferred from electronic annotation. Source: Compara
Molecular_function	sequence-specific DNA binding Inferred from electronic annotation. Source: Compara sequence-specific DNA binding transcription factor activity Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7ZAP5 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 170DF8E54E6FC73C	FASTA	439	45,468
	10 20 30 40 50 60 MNSGLGSMNS MNTYMTMNTM TTSGNMTPAS FNMSYANPGL GAGLSPGAVA GMPGGSAGAM 70 80 90 100 110 120 NSMTAAGVTA MGTALSPSGM GAMGAQQAAS MNGLGPYAAA MNPCMSPMAY APSNLGRSRA 130 140 150 160 170 180 GGGGDAKTFK RSYPHAKPPY SYISLITMAI QQAPSKMLTL SEIYQWIMDL FPYYRQNQQR 190 200 210 220 230 240 WQNSIRHSLS FNDCFVKVAR SPDKPGKGSY WTLHPDSGNM FENGCYLRRQ KRFKCEKQPG 250 260 270 280 290 300 AGGGGGSGSG GSGAKGGPES RKDPSGASNP SADSPLHRGV HGKTGQLEGA PAPGPAASPQ 310 320 330 340 350 360 TLDHSGATAT GGASELKTPA SSTAPPISSG PGALASVPAS HPAHGLAPHE SQLHLKGDPH 370 380 390 400 410 420 YSFNHPFSIN NLMSSSEQQH KLDFKAYEQA LQYSPYGSTL PASLPLGSAS VTTRSPIEPS 430 ALEPAYYQGV YSRPVLNTS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and analysis of human chromosome 14." Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H. , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J. Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Breast EMBL BAH14731.1.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL121790 Genomic DNA. No translation available. AK316360 mRNA. Translation: BAH14731.1.
IPI	IPI00024387.
3D structure databases
SMR	B7ZAP5. Positions 135-234.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000540786; ENSP00000440178; ENSG00000129514.
Organism-specific databases
HGNC	HGNC:5021. FOXA1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG006621.
Gene expression databases
ArrayExpress	B7ZAP5.
Family and domain databases
Gene3D	1.10.10.10. 1 hit.
InterPro	IPR013638. Fork-head_N. IPR018533. Forkhead_box_C. IPR001766. TF_fork_head. IPR018122. TF_fork_head_CS. IPR011991. WHTH_DNA-bd_dom. [Graphical view]
Pfam	PF00250. Fork_head. 1 hit. PF08430. Fork_head_N. 1 hit. PF09354. HNF_C. 1 hit. [Graphical view]
PRINTS	PR00053. FORKHEAD.
SMART	SM00339. FH. 1 hit. [Graphical view]
PROSITE	PS00657. FORK_HEAD_1. 1 hit. PS00658. FORK_HEAD_2. 1 hit. PS50039. FORK_HEAD_3. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	FOXA1. human.
NextBio	35480927.

Entry information

Entry name

B7ZAP5_HUMAN

Accession

Primary (citable) accession number: B7ZAP5

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.