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B7ZAP5 (B7ZAP5_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

cDNA, FLJ79259, highly similar to Hepatocyte nuclear factor 3-alpha EMBL BAH14731.1
Gene names
Name:FOXA1 Ensembl ENSP00000440178
OrganismHomo sapiens (Human) [Reference proteome] EMBL BAH14731.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length439 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains fork-head DNA-binding domain. SAAS SAAS001766

Ontologies

Keywords
   LigandDNA-binding SAAS SAAS001766
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processanatomical structure formation involved in morphogenesis

Inferred from electronic annotation. Source: Ensembl

chromatin remodeling

Inferred from electronic annotation. Source: Ensembl

dorsal/ventral neural tube patterning

Inferred from electronic annotation. Source: Ensembl

epithelial cell maturation involved in prostate gland development

Inferred from electronic annotation. Source: Ensembl

epithelial tube branching involved in lung morphogenesis

Inferred from electronic annotation. Source: Ensembl

epithelial-mesenchymal signaling involved in prostate gland development

Inferred from electronic annotation. Source: Ensembl

glucose homeostasis

Inferred from electronic annotation. Source: Ensembl

hormone metabolic process

Inferred from electronic annotation. Source: Ensembl

lung epithelial cell differentiation

Inferred from electronic annotation. Source: Ensembl

neuron fate specification

Inferred from electronic annotation. Source: Ensembl

positive regulation of neuron differentiation

Inferred from electronic annotation. Source: Ensembl

positive regulation of smoothened signaling pathway

Inferred from electronic annotation. Source: Ensembl

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Ensembl

prostate gland epithelium morphogenesis

Inferred from electronic annotation. Source: Ensembl

prostate gland stromal morphogenesis

Inferred from electronic annotation. Source: Ensembl

regulation of cell cycle

Inferred from electronic annotation. Source: Ensembl

secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentnucleus

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionsequence-specific DNA binding

Inferred from electronic annotation. Source: Ensembl

sequence-specific DNA binding transcription factor activity

Inferred from electronic annotation. Source: Ensembl

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B7ZAP5 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 170DF8E54E6FC73C

FASTA43945,468
        10         20         30         40         50         60 
MNSGLGSMNS MNTYMTMNTM TTSGNMTPAS FNMSYANPGL GAGLSPGAVA GMPGGSAGAM 

        70         80         90        100        110        120 
NSMTAAGVTA MGTALSPSGM GAMGAQQAAS MNGLGPYAAA MNPCMSPMAY APSNLGRSRA 

       130        140        150        160        170        180 
GGGGDAKTFK RSYPHAKPPY SYISLITMAI QQAPSKMLTL SEIYQWIMDL FPYYRQNQQR 

       190        200        210        220        230        240 
WQNSIRHSLS FNDCFVKVAR SPDKPGKGSY WTLHPDSGNM FENGCYLRRQ KRFKCEKQPG 

       250        260        270        280        290        300 
AGGGGGSGSG GSGAKGGPES RKDPSGASNP SADSPLHRGV HGKTGQLEGA PAPGPAASPQ 

       310        320        330        340        350        360 
TLDHSGATAT GGASELKTPA SSTAPPISSG PGALASVPAS HPAHGLAPHE SQLHLKGDPH 

       370        380        390        400        410        420 
YSFNHPFSIN NLMSSSEQQH KLDFKAYEQA LQYSPYGSTL PASLPLGSAS VTTRSPIEPS 

       430 
ALEPAYYQGV YSRPVLNTS 

« Hide

References

« Hide 'large scale' references
[1]"The DNA sequence and analysis of human chromosome 14."
Heilig R., Eckenberg R., Petit J.-L., Fonknechten N., Da Silva C., Cattolico L., Levy M., Barbe V., De Berardinis V., Ureta-Vidal A., Pelletier E., Vico V., Anthouard V., Rowen L., Madan A., Qin S., Sun H., Du H. expand/collapse author list , Pepin K., Artiguenave F., Robert C., Cruaud C., Bruels T., Jaillon O., Friedlander L., Samson G., Brottier P., Cure S., Segurens B., Aniere F., Samain S., Crespeau H., Abbasi N., Aiach N., Boscus D., Dickhoff R., Dors M., Dubois I., Friedman C., Gouyvenoux M., James R., Madan A., Mairey-Estrada B., Mangenot S., Martins N., Menard M., Oztas S., Ratcliffe A., Shaffer T., Trask B., Vacherie B., Bellemere C., Belser C., Besnard-Gonnet M., Bartol-Mavel D., Boutard M., Briez-Silla S., Combette S., Dufosse-Laurent V., Ferron C., Lechaplais C., Louesse C., Muselet D., Magdelenat G., Pateau E., Petit E., Sirvain-Trukniewicz P., Trybou A., Vega-Czarny N., Bataille E., Bluet E., Bordelais I., Dubois M., Dumont C., Guerin T., Haffray S., Hammadi R., Muanga J., Pellouin V., Robert D., Wunderle E., Gauguet G., Roy A., Sainte-Marthe L., Verdier J., Verdier-Discala C., Hillier L.W., Fulton L., McPherson J., Matsuda F., Wilson R., Scarpelli C., Gyapay G., Wincker P., Saurin W., Quetier F., Waterston R., Hood L., Weissenbach J.
Nature 421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"NEDO human cDNA sequencing project."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Breast EMBL BAH14731.1.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL121790 Genomic DNA. No translation available.
AK316360 mRNA. Translation: BAH14731.1.
UniGeneHs.163484.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000540786; ENSP00000440178; ENSG00000129514.
KEGGhsa:3169.

Organism-specific databases

CTD3169.
HGNCHGNC:5021. FOXA1.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG006621.
KOK09387.

Family and domain databases

Gene3D1.10.10.10. 1 hit.
InterProIPR013638. Fork-head_N.
IPR018533. Forkhead_box_C.
IPR001766. TF_fork_head.
IPR018122. TF_fork_head_CS.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamPF00250. Fork_head. 1 hit.
PF08430. Fork_head_N. 1 hit.
PF09354. HNF_C. 1 hit.
[Graphical view]
PRINTSPR00053. FORKHEAD.
SMARTSM00339. FH. 1 hit.
[Graphical view]
PROSITEPS00657. FORK_HEAD_1. 1 hit.
PS00658. FORK_HEAD_2. 1 hit.
PS50039. FORK_HEAD_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSFOXA1. human.
GenomeRNAi3169.
NextBio35480927.

Entry information

Entry nameB7ZAP5_HUMAN
AccessionPrimary (citable) accession number: B7ZAP5
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 16, 2014
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.