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Protein
Submitted name:

cDNA, FLJ78903, highly similar to Mitogen-activated protein kinase kinase kinase 7-interacting protein 1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. kinase activator activity Source: Ensembl
  2. kinase activity Source: UniProtKB-KW

GO - Biological processi

  1. activation of MAPKKK activity Source: Ensembl
  2. heart morphogenesis Source: Ensembl
  3. in utero embryonic development Source: Ensembl
  4. lung development Source: Ensembl
  5. positive regulation of MAP kinase activity Source: Ensembl
  6. transforming growth factor beta receptor signaling pathway Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA, FLJ78903, highly similar to Mitogen-activated protein kinase kinase kinase 7-interacting protein 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. protein complex Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB7Z9N9.

Expressioni

Gene expression databases

BgeeiB7Z9N9.
ExpressionAtlasiB7Z9N9. baseline and differential.

Interactioni

Structurei

3D structure databases

ProteinModelPortaliB7Z9N9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG007302.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z9N9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVVAVLLNN KLYVANVGTN RALLCKSTVD GLQVTQLNVD HTTENEDELF
60 70 80 90 100
RLSQLGLDAG KIKQVGIICG QESTRRIGDY KVKYGYTDID LLSAAKSKPI
110 120 130 140 150
IAEPEIHGAQ PLDGVTGFLV LMSEGLYKAL EAAHGPGQAN QEIAAMIDTE
160 170 180 190 200
FAKQTSLDAV AQAVVDRVKR IHSDTFASGG ERARFCPRHE DMTLLVRNFG
210 220 230 240 250
YPLGEMSQPT PSPAPAAGGR VYPVSVPYSS AQSTSKTSVT LSLVMPSQGQ
260 270 280 290 300
MVNGAHSAST LDEATPTLTN QSPTLTLQST NTHTQSSSSS SDGGLFRSRP
310 320 330
AHSLPPGEDG RVEPYVDFAE FYRLWSVDHG EQSVVTAP
Length:338
Mass (Da):36,178
Last modified:March 3, 2009 - v1
Checksum:i6F88F8DFEF3B8050
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK316004 mRNA. Translation: BAH14375.1.
UniGeneiHs.507681.
Hs.729080.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK316004 mRNA. Translation: BAH14375.1.
UniGeneiHs.507681.
Hs.729080.

3D structure databases

ProteinModelPortaliB7Z9N9.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiB7Z9N9.

Proteomic databases

PRIDEiB7Z9N9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG007302.

Miscellaneous databases

NextBioi35480765.

Gene expression databases

BgeeiB7Z9N9.
ExpressionAtlasiB7Z9N9. baseline and differential.

Family and domain databases

Gene3Di3.60.40.10. 1 hit.
InterProiIPR001932. PP2C-like_dom.
IPR015655. Protein_Pase_2C.
[Graphical view]
PANTHERiPTHR13832. PTHR13832. 1 hit.
PfamiPF00481. PP2C. 1 hit.
[Graphical view]
SMARTiSM00332. PP2Cc. 1 hit.
[Graphical view]
SUPFAMiSSF81606. SSF81606. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.

Entry informationi

Entry nameiB7Z9N9_HUMAN
AccessioniPrimary (citable) accession number: B7Z9N9
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.