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Protein
Submitted name:

cDNA, FLJ78862, highly similar to Isocitrate dehydrogenase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA, FLJ78862, highly similar to Isocitrate dehydrogenaseImported
Submitted name:
cDNA, FLJ78950, highly similar to Isocitrate dehydrogenaseImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB7Z9J8.

Expressioni

Gene expression databases

BgeeiB7Z9J8.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000299518.

Structurei

3D structure databases

ProteinModelPortaliB7Z9J8.
SMRiB7Z9J8. Positions 1-253.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the isocitrate and isopropylmalate dehydrogenases family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG052080.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z9J8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLLLRKTFD LYANVRPCVS IEGYKTPYTD VNIVTIRENT EGEYSGIEHV
60 70 80 90 100
IVDGVVQSIK LITEGASKRI AEFAFEYARN NHRSNVTAVH KANIMRMSDG
110 120 130 140 150
LFLQKCREVA ESCKDIKFNE MYLDTVCLNM VQDPSQFDVL VMPNLYGDIL
160 170 180 190 200
SDLCAGLIGG LGVTPSGNIG ANGVAIFESV HGTAPDIAGK DMANPTALLL
210 220 230 240 250
SAVMMLRHMG LFDHAARIEA ACFATIKDGK SLTKDLGGNA KCSDFTEEIC

RRVKDLD
Length:257
Mass (Da):28,134
Last modified:March 3, 2009 - v1
Checksum:iC6EB9E5007465DC8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315963 mRNA. Translation: BAH14334.1.
AK316051 mRNA. Translation: BAH14422.1.
RefSeqiXP_005254393.1. XM_005254336.1.
XP_005254394.1. XM_005254337.1.
UniGeneiHs.591110.

Genome annotation databases

GeneIDi3419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315963 mRNA. Translation: BAH14334.1.
AK316051 mRNA. Translation: BAH14422.1.
RefSeqiXP_005254393.1. XM_005254336.1.
XP_005254394.1. XM_005254337.1.
UniGeneiHs.591110.

3D structure databases

ProteinModelPortaliB7Z9J8.
SMRiB7Z9J8. Positions 1-253.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000299518.

Proteomic databases

PRIDEiB7Z9J8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3419.

Organism-specific databases

CTDi3419.

Phylogenomic databases

HOVERGENiHBG052080.

Miscellaneous databases

ChiTaRSiIDH3A. human.
GenomeRNAii3419.
NextBioi35480743.

Gene expression databases

BgeeiB7Z9J8.

Family and domain databases

Gene3Di3.40.718.10. 1 hit.
InterProiIPR019818. IsoCit/isopropylmalate_DH_CS.
IPR001804. Isocitrate/isopropylmalate_DH.
IPR024084. IsoPropMal-DH-like_dom.
[Graphical view]
PANTHERiPTHR11835. PTHR11835. 1 hit.
PfamiPF00180. Iso_dh. 1 hit.
[Graphical view]
PROSITEiPS00470. IDH_IMDH. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: AmygdalaImported and HippocampusImported.

Entry informationi

Entry nameiB7Z9J8_HUMAN
AccessioniPrimary (citable) accession number: B7Z9J8
Secondary accession number(s): E7EWD2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 22, 2015
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.