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Protein
Submitted name:

cDNA FLJ52037, highly similar to GRB2-related adapter protein 2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

Enzyme and pathway databases

SignaLinkiB7Z8E3.

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52037, highly similar to GRB2-related adapter protein 2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PaxDbiB7Z8E3.
PeptideAtlasiB7Z8E3.
PRIDEiB7Z8E3.

Expressioni

Gene expression databases

BgeeiENSG00000100351.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000339186.

Structurei

3D structure databases

ProteinModelPortaliB7Z8E3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 77SH2InterPro annotationAdd BLAST77
Domaini199 – 258SH3InterPro annotationAdd BLAST60

Sequence similaritiesi

Contains 1 SH3 domain.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3601. Eukaryota.
ENOG410XR1G. LUCA.
HOVERGENiHBG005404.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z8E3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKEVGFFII RASQSSPGDF SISVRHEDDV QHFKVMRDNK GNYFLWTEKF
60 70 80 90 100
PSLNKLVDYY RTNSISRQKQ IFLRDRTRED QGHRGNSLDR RSQGGPHLSG
110 120 130 140 150
AVGEEIRPSM NRKLSDHPPT LPLQQHQHQP QPPQYAPAPQ QLQQPPQQRY
160 170 180 190 200
LQHHHFHQER RGGSLDINDG HCGTGLGSEM NAALMHRRHT DPVQLQAAGR
210 220 230 240 250
VRWARALYDF EALEDDELGF HSGEVVEVLD SSNPSWWTGR LHNKLGLFPA

NYVAPMTR
Length:258
Mass (Da):29,625
Last modified:March 3, 2009 - v1
Checksum:iD975950B906D36CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK303280 mRNA. Translation: BAH13929.1.
RefSeqiNP_001278755.1. NM_001291826.1.
XP_006724439.1. XM_006724376.3.
UniGeneiHs.517499.

Genome annotation databases

GeneIDi9402.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK303280 mRNA. Translation: BAH13929.1.
RefSeqiNP_001278755.1. NM_001291826.1.
XP_006724439.1. XM_006724376.3.
UniGeneiHs.517499.

3D structure databases

ProteinModelPortaliB7Z8E3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000339186.

Proteomic databases

PaxDbiB7Z8E3.
PeptideAtlasiB7Z8E3.
PRIDEiB7Z8E3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi9402.

Organism-specific databases

CTDi9402.

Phylogenomic databases

eggNOGiKOG3601. Eukaryota.
ENOG410XR1G. LUCA.
HOVERGENiHBG005404.

Enzyme and pathway databases

SignaLinkiB7Z8E3.

Miscellaneous databases

ChiTaRSiGRAP2. human.
GenomeRNAii9402.

Gene expression databases

BgeeiENSG00000100351.

Family and domain databases

Gene3Di3.30.505.10. 1 hit.
InterProiIPR000980. SH2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00017. SH2. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00401. SH2DOMAIN.
PR00452. SH3DOMAIN.
SMARTiSM00252. SH2. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
SSF55550. SSF55550. 1 hit.
PROSITEiPS50001. SH2. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB7Z8E3_HUMAN
AccessioniPrimary (citable) accession number: B7Z8E3
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 30, 2016
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.