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B7Z845

- B7Z845_HUMAN

UniProt

B7Z845 - B7Z845_HUMAN

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Protein
Submitted name: Desmoglein-1
Gene
DSG1
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. homophilic cell adhesion Source: InterPro
  2. maternal process involved in female pregnancy Source: Ensembl
  3. response to progesterone Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Desmoglein-1Imported
Submitted name:
cDNA FLJ50928, highly similar to Desmoglein-1Imported
Gene namesi
Name:DSG1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 18

Organism-specific databases

HGNCiHGNC:3048. DSG1.

Subcellular locationi

GO - Cellular componenti

  1. apical plasma membrane Source: Ensembl
  2. lateral plasma membrane Source: Ensembl
Complete GO annotation...

Structurei

3D structure databases

ProteinModelPortaliB7Z845.
SMRiB7Z845. Positions 65-120.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG106305.

Family and domain databases

Gene3Di4.10.900.10. 1 hit.
InterProiIPR000233. Cadherin_cytoplasmic-dom.
IPR027397. Catenin_binding_dom.
IPR009123. Desmoglein.
IPR009122. Desmosomal_cadherin.
[Graphical view]
PANTHERiPTHR24025. PTHR24025. 1 hit.
PfamiPF01049. Cadherin_C. 1 hit.
[Graphical view]
PRINTSiPR01818. DESMOCADHERN.
PR01819. DESMOGLEIN.

Sequencei

Sequence statusi: Complete.

B7Z845-1 [UniParc]FASTAAdd to Basket

« Hide

MQDLGGGERM TGFELTEGVK TSGMPEICQE YSGTLRRNSM RECREGGLNM    50
NFMESYFCQK AYAYADEDEG RPSNDCLLIY DIEGVGSPAG SVGCCSFIGE 100
DLDDSFLDTL GPKFKKLADI SLGKESYPDL DPSWPPQSTE PVCLPQETEP 150
VVSGHPPISP HFGTTTVISE STYPSGPGVL HPKPILDPLG YGNVTVTESY 200
TTSDTLKPSV HVHDNRPASN VVVTERVVGP ISGADLHGML EMPDLRDGSN 250
VIVTERVIAP SSSLPTSLTI HHPRESSNVV VTERVIQPTS GMIGSLSMHP 300
ELANAHNVIV TERVVSGAGV TGISGTTGIS GGIGSSGLVG TSMGAGSGAL 350
SGAGISGGGI GLSSLGGTAS IGHMRSSSDH HFNQTIGSAS PSTARSRITK 400
YSTVQYSK 408
Length:408
Mass (Da):42,619
Last modified:March 3, 2009 - v1
Checksum:iA910C8D97368B725
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC009717 Genomic DNA. No translation available.
AK302888 mRNA. Translation: BAH13831.1.
UniGeneiHs.2633.

Genome annotation databases

EnsembliENST00000462981; ENSP00000462666; ENSG00000134760.
UCSCiuc010xbp.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC009717 Genomic DNA. No translation available.
AK302888 mRNA. Translation: BAH13831.1 .
UniGenei Hs.2633.

3D structure databases

ProteinModelPortali B7Z845.
SMRi B7Z845. Positions 65-120.
ModBasei Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000462981 ; ENSP00000462666 ; ENSG00000134760 .
UCSCi uc010xbp.2. human.

Organism-specific databases

HGNCi HGNC:3048. DSG1.
GenAtlasi Search...

Phylogenomic databases

HOVERGENi HBG106305.

Miscellaneous databases

NextBioi 35480388.

Family and domain databases

Gene3Di 4.10.900.10. 1 hit.
InterProi IPR000233. Cadherin_cytoplasmic-dom.
IPR027397. Catenin_binding_dom.
IPR009123. Desmoglein.
IPR009122. Desmosomal_cadherin.
[Graphical view ]
PANTHERi PTHR24025. PTHR24025. 1 hit.
Pfami PF01049. Cadherin_C. 1 hit.
[Graphical view ]
PRINTSi PR01818. DESMOCADHERN.
PR01819. DESMOGLEIN.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: TestisImported.
  3. Ensembl
    Submitted (AUG-2012) to UniProtKB
    Cited for: IDENTIFICATION.

Entry informationi

Entry nameiB7Z845_HUMAN
AccessioniPrimary (citable) accession number: B7Z845
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 11, 2014
This is version 30 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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