B7Z845 (B7Z845_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Desmoglein-1 Ensembl ENSP00000462666

Submitted name:
cDNA FLJ50928, highly similar to Desmoglein-1 EMBL BAH13831.1

Gene names

Name:

DSG1 Ensembl ENSP00000462666

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAH13831.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	408 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	homophilic cell adhesion Inferred from electronic annotation. Source: InterPro maternal process involved in female pregnancy Inferred from electronic annotation. Source: Compara response to progesterone stimulus Inferred from electronic annotation. Source: Compara
Cellular_component	apical plasma membrane Inferred from electronic annotation. Source: Compara lateral plasma membrane Inferred from electronic annotation. Source: Compara
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7Z845 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: A910C8D97368B725	FASTA	408	42,619
	10 20 30 40 50 60 MQDLGGGERM TGFELTEGVK TSGMPEICQE YSGTLRRNSM RECREGGLNM NFMESYFCQK 70 80 90 100 110 120 AYAYADEDEG RPSNDCLLIY DIEGVGSPAG SVGCCSFIGE DLDDSFLDTL GPKFKKLADI 130 140 150 160 170 180 SLGKESYPDL DPSWPPQSTE PVCLPQETEP VVSGHPPISP HFGTTTVISE STYPSGPGVL 190 200 210 220 230 240 HPKPILDPLG YGNVTVTESY TTSDTLKPSV HVHDNRPASN VVVTERVVGP ISGADLHGML 250 260 270 280 290 300 EMPDLRDGSN VIVTERVIAP SSSLPTSLTI HHPRESSNVV VTERVIQPTS GMIGSLSMHP 310 320 330 340 350 360 ELANAHNVIV TERVVSGAGV TGISGTTGIS GGIGSSGLVG TSMGAGSGAL SGAGISGGGI 370 380 390 400 GLSSLGGTAS IGHMRSSSDH HFNQTIGSAS PSTARSRITK YSTVQYSK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"DNA sequence and analysis of human chromosome 18." Nusbaum C., Zody M.C., Borowsky M.L., Kamal M., Kodira C.D., Taylor T.D., Whittaker C.A., Chang J.L., Cuomo C.A., Dewar K., FitzGerald M.G., Yang X., Abouelleil A., Allen N.R., Anderson S., Bloom T., Bugalter B., Butler J. , Cook A., DeCaprio D., Engels R., Garber M., Gnirke A., Hafez N., Hall J.L., Norman C.H., Itoh T., Jaffe D.B., Kuroki Y., Lehoczky J., Lui A., Macdonald P., Mauceli E., Mikkelsen T.S., Naylor J.W., Nicol R., Nguyen C., Noguchi H., O'Leary S.B., O'Neill K., Piqani B., Smith C.L., Talamas J.A., Topham K., Totoki Y., Toyoda A., Wain H.M., Young S.K., Zeng Q., Zimmer A.R., Fujiyama A., Hattori M., Birren B.W., Sakaki Y., Lander E.S. Nature 437:551-555(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Testis EMBL BAH13831.1.
[3]	Ensembl Submitted (AUG-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC009717 Genomic DNA. No translation available. AK302888 mRNA. Translation: BAH13831.1.
IPI	IPI00025753.
UniGene	Hs.2633.
3D structure databases
SMR	B7Z845. Positions 65-121.
ModBase	Search...
Proteomic databases
PRIDE	B7Z845.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000462981; ENSP00000462666; ENSG00000134760.
UCSC	uc010xbp.2. human.
Organism-specific databases
HGNC	HGNC:3048. DSG1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG106305.
Gene expression databases
ArrayExpress	B7Z845.
Family and domain databases
InterPro	IPR000233. Cadherin_cytoplasmic-dom. IPR009123. Desmoglein. IPR009122. Desmosomal_cadherin. [Graphical view]
PANTHER	PTHR24025. PTHR24025. 1 hit.
Pfam	PF01049. Cadherin_C. 1 hit. [Graphical view]
PRINTS	PR01818. DESMOCADHERN. PR01819. DESMOGLEIN.
ProtoNet	Search...
Other
NextBio	35480388.

Entry information

Entry name

B7Z845_HUMAN

Accession

Primary (citable) accession number: B7Z845

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 21 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.