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B7Z7N6

- B7Z7N6_HUMAN

UniProt

B7Z7N6 - B7Z7N6_HUMAN

Protein
Submitted name:

cDNA FLJ51565, highly similar to Pyruvate dehydrogenase (lipoamide) kinase isozyme 1 (EC 2.7.11.2)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 43 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. kinase activity Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of acetyl-CoA biosynthetic process from pyruvate Source: Ensembl

    Keywords - Molecular functioni

    KinaseImported, Transferase

    Keywords - Ligandi

    PyruvateImported

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ51565, highly similar to Pyruvate dehydrogenase (lipoamide) kinase isozyme 1 (EC 2.7.11.2)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial pyruvate dehydrogenase complex Source: Ensembl

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG000511.

    Family and domain databases

    Gene3Di1.20.140.20. 1 hit.
    3.30.565.10. 1 hit.
    InterProiIPR018955. BCDHK/PDK_N.
    IPR003594. HATPase_ATP-bd.
    IPR005467. Sig_transdc_His_kinase_core.
    [Graphical view]
    PfamiPF10436. BCDHK_Adom3. 1 hit.
    PF02518. HATPase_c. 1 hit.
    [Graphical view]
    SMARTiSM00387. HATPase_c. 1 hit.
    [Graphical view]
    SUPFAMiSSF55874. SSF55874. 1 hit.
    SSF69012. SSF69012. 1 hit.
    PROSITEiPS50109. HIS_KIN. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7Z7N6-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFLRQELPVR LANIMKEISL LPDNLLRTPS VQLVQSWYIQ SLQELLDFKD    50
    KSAEDAKAIY DFTDTVIRIR NRHNDVIPTM AQGVIEYKES FGVDPVTSQN 100
    VQYFLDRFYM SRISIRMLLN QHSLLFGGKG KGSPSHRKHI GSINPNCNVL 150
    EVIKDGYENA RRLCDLYYIN SPELELEELN AKSPGQPIQV VYVPSHLYHM 200
    VFELFKNAMR ATMEHHANRG VYPPIQVHVT LGNEDLTVKM SDRGGGVPLR 250
    KIDRLFNYMY STAPRPRVET SRAVPLAGFG YGLPISRLYA QYFQGDLKLY 300
    SLEGYGTDAV IYIKALSTDS IERLPVYNKA AWKHYNTNHE ADDWCVPSRE 350
    PKDMTTFRSA 360
    Length:360
    Mass (Da):41,303
    Last modified:March 3, 2009 - v1
    Checksum:i4B86ADECF096D0F5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK302321 mRNA. Translation: BAH13672.1.
    UniGeneiHs.470633.
    Hs.733780.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK302321 mRNA. Translation: BAH13672.1 .
    UniGenei Hs.470633.
    Hs.733780.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG000511.

    Miscellaneous databases

    ChiTaRSi Pdk1. human.
    NextBioi 35480274.

    Family and domain databases

    Gene3Di 1.20.140.20. 1 hit.
    3.30.565.10. 1 hit.
    InterProi IPR018955. BCDHK/PDK_N.
    IPR003594. HATPase_ATP-bd.
    IPR005467. Sig_transdc_His_kinase_core.
    [Graphical view ]
    Pfami PF10436. BCDHK_Adom3. 1 hit.
    PF02518. HATPase_c. 1 hit.
    [Graphical view ]
    SMARTi SM00387. HATPase_c. 1 hit.
    [Graphical view ]
    SUPFAMi SSF55874. SSF55874. 1 hit.
    SSF69012. SSF69012. 1 hit.
    PROSITEi PS50109. HIS_KIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: TestisImported.
    2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiB7Z7N6_HUMAN
    AccessioniPrimary (citable) accession number: B7Z7N6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 43 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.