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Protein

Kinesin-like protein

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi235 – 242ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionMotor proteinPROSITE-ProRule annotation
LigandATP-bindingPROSITE-ProRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Kinesin-like proteinUniRule annotation
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

MicrotubuleUniRule annotation

PTM / Processingi

Proteomic databases

EPDiB7Z7M6
MaxQBiB7Z7M6
PeptideAtlasiB7Z7M6
PRIDEiB7Z7M6

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB7Z7M6
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini145 – 475Kinesin motorInterPro annotationAdd BLAST331

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili78 – 110Sequence analysisAdd BLAST33
Coiled coili521 – 545Sequence analysisAdd BLAST25

Sequence similaritiesi

Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG0246 Eukaryota
COG5059 LUCA
HOGENOMiHOG000231329
HOVERGENiHBG003875

Family and domain databases

Gene3Di3.40.850.10, 1 hit
InterProiView protein in InterPro
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase
PANTHERiPTHR24115 PTHR24115, 1 hit
PfamiView protein in Pfam
PF00225 Kinesin, 1 hit
PRINTSiPR00380 KINESINHEAVY
SMARTiView protein in SMART
SM00129 KISc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
PROSITEiView protein in PROSITE
PS00411 KINESIN_MOTOR_1, 1 hit
PS50067 KINESIN_MOTOR_2, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z7M6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTVSELRIT AQENDMEVEL PAAANSRKQF SVPPAPTRPS CPAVAEIPLR
60 70 80 90 100
MVSEEMEEQV HSIRGSSSAN PVNSVRRKSC LVKEVEKMKN KREEKKAQNS
110 120 130 140 150
EMRMKRAQEY DSSFPNWEFA RMIKEFRATL ECHPLTMTDP IEEHRICVCV
160 170 180 190 200
RKRPLNKQEL AKKEIDVISI PSKCLLLVHE PKLKVDLTKY LENQAFCFDF
210 220 230 240 250
AFDETASNEV VYRFTARPLV QTIFEGGKAT CFAYGQTGSG KTHTMGGDLS
260 270 280 290 300
GKAQNASKGI YAMASRDVFL LKNQPCYRKL GLEVYVTFFE IYNGKLFDLL
310 320 330 340 350
NKKAKLRVLE DGKQQVQVVG LQEHLVNSAD DVIKMIDMGS ACRTSGQTFA
360 370 380 390 400
NSNSSRSHAC FQIILRAKGR MHGKFSLVDL AGNERGADTS SADRQTRMEG
410 420 430 440 450
AEINKSLLAL KECIRALGQN KAHTPFRESK LTQVLRDSFI GENSRTCMIA
460 470 480 490 500
TISPGISSCE YTLNTLRYAD RVKELSPHSG PSGEQLIQME TEEMEACSNG
510 520 530 540 550
ALIPGNLSKE EEELSSQMSS FNEAMTQIRE LEEKAMEELK EIIQQGPDWL
560 570 580 590 600
ELSEMTEQPD YDLETFVNKA ESALAQQAKH FSALRDVIKA LRLAMQLEEQ
610
ASRQISSKKR PQ
Length:612
Mass (Da):68,819
Last modified:March 3, 2009 - v1
Checksum:i9C141EF3FDF60181
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302267 mRNA Translation: BAH13662.1
RefSeqiNP_001284585.1, NM_001297656.1
NP_001284586.1, NM_001297657.1
XP_011538842.1, XM_011540540.2
XP_011538843.1, XM_011540541.2
UniGeneiHs.720061

Genome annotation databases

GeneIDi11004

Similar proteinsi

Entry informationi

Entry nameiB7Z7M6_HUMAN
AccessioniPrimary (citable) accession number: B7Z7M6
Secondary accession number(s): E9PDS6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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Main funding by: National Institutes of Health