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Protein
Submitted name:

cDNA FLJ50281, highly similar to Glucocorticoid receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi21 – 96Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50281, highly similar to Glucocorticoid receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

  • Nucleus PROSITE-ProRule annotationSAAS annotation

GO - Cellular componenti

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiB7Z7I2.
PaxDbiB7Z7I2.
PeptideAtlasiB7Z7I2.

Expressioni

Gene expression databases

BgeeiENSG00000113580.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000231509.

Structurei

3D structure databases

ProteinModelPortaliB7Z7I2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 96Nuclear receptor DNA-bindingInterPro annotationAdd BLAST76

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG007583.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z7I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPDVSSPPS SSSTATTGPP PKLCLVCSDE ASGCHYGVLT CGSCKVFFKR
60 70 80 90 100
AVEGQHNYLC AGRNDCIIDK IRRKNCPACR YRKCLQAGMN LEARKTKKKI
110 120 130 140 150
KGIQQATTGV SQETSENPGN KTIVPATLPQ LTPTLVSLLE VIEPEVLYAG
160 170 180 190 200
YDSSVPDSTW RIMTTLNMLG GRQVIAAVKW AKAIPGFRNL HLDDQMTLLQ
210 220 230 240 250
YSWMFLMAFA LGWRSYRQSS ANLLCFAPDL IINEQRMTLP CMYDQCKHML
260 270 280 290 300
YVSSELHRLQ VSYEEYLCMK TLLLLSSVPK DGLKSQELFD EIRMTYIKEL
310 320 330 340 350
GKAIVKREGN SSQNWQRFYQ LTKLLDSMHE VVENLLNYCF QTFLDKTMSI
360 370 380
EFPEMLAEII TNQIPKYSNG NIKKLLFHQK
Length:380
Mass (Da):43,149
Last modified:March 3, 2009 - v1
Checksum:i3D3F7C55D300C99F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302050 mRNA. Translation: BAH13618.1.
RefSeqiXP_011535939.1. XM_011537637.2.
UniGeneiHs.122926.

Genome annotation databases

GeneIDi2908.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302050 mRNA. Translation: BAH13618.1.
RefSeqiXP_011535939.1. XM_011537637.2.
UniGeneiHs.122926.

3D structure databases

ProteinModelPortaliB7Z7I2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000231509.

Proteomic databases

MaxQBiB7Z7I2.
PaxDbiB7Z7I2.
PeptideAtlasiB7Z7I2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2908.

Organism-specific databases

CTDi2908.

Phylogenomic databases

eggNOGiKOG3575. Eukaryota.
ENOG410XRZC. LUCA.
HOVERGENiHBG007583.

Miscellaneous databases

ChiTaRSiNR3C1. human.
GenomeRNAii2908.

Gene expression databases

BgeeiENSG00000113580.

Family and domain databases

Gene3Di3.30.50.10. 1 hit.
InterProiView protein in InterPro
IPR000536. Nucl_hrmn_rcpt_lig-bd.
IPR001723. Nuclear_hrmn_rcpt.
IPR001628. Znf_hrmn_rcpt.
IPR013088. Znf_NHR/GATA.
PfamiView protein in Pfam
PF00104. Hormone_recep. 1 hit.
PF00105. zf-C4. 1 hit.
PRINTSiPR00398. STRDHORMONER.
PR00047. STROIDFINGER.
SMARTiView protein in SMART
SM00430. HOLI. 1 hit.
SM00399. ZnF_C4. 1 hit.
SUPFAMiSSF48508. SSF48508. 1 hit.
PROSITEiView protein in PROSITE
PS00031. NUCLEAR_REC_DBD_1. 1 hit.
PS51030. NUCLEAR_REC_DBD_2. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB7Z7I2_HUMAN
AccessioniPrimary (citable) accession number: B7Z7I2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 7, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.