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Protein
Submitted name:

cDNA FLJ50281, highly similar to Glucocorticoid receptor

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi21 – 96Nuclear receptorPROSITE-ProRule annotationAdd BLAST76

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorUniRule annotationSAAS annotationImported
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50281, highly similar to Glucocorticoid receptorImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

MaxQBiB7Z7I2
PeptideAtlasiB7Z7I2
PRIDEiB7Z7I2

Structurei

3D structure databases

ProteinModelPortaliB7Z7I2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 96Nuclear receptorInterPro annotationAdd BLAST76
Domaini127 – 361NR LBDInterPro annotationAdd BLAST235

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.UniRule annotationSAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3575 Eukaryota
ENOG410XRZC LUCA
HOVERGENiHBG007583

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001723 Nuclear_hrmn_rcpt
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00398 STRDHORMONER
PR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 1 hit
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z7I2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPDVSSPPS SSSTATTGPP PKLCLVCSDE ASGCHYGVLT CGSCKVFFKR
60 70 80 90 100
AVEGQHNYLC AGRNDCIIDK IRRKNCPACR YRKCLQAGMN LEARKTKKKI
110 120 130 140 150
KGIQQATTGV SQETSENPGN KTIVPATLPQ LTPTLVSLLE VIEPEVLYAG
160 170 180 190 200
YDSSVPDSTW RIMTTLNMLG GRQVIAAVKW AKAIPGFRNL HLDDQMTLLQ
210 220 230 240 250
YSWMFLMAFA LGWRSYRQSS ANLLCFAPDL IINEQRMTLP CMYDQCKHML
260 270 280 290 300
YVSSELHRLQ VSYEEYLCMK TLLLLSSVPK DGLKSQELFD EIRMTYIKEL
310 320 330 340 350
GKAIVKREGN SSQNWQRFYQ LTKLLDSMHE VVENLLNYCF QTFLDKTMSI
360 370 380
EFPEMLAEII TNQIPKYSNG NIKKLLFHQK
Length:380
Mass (Da):43,149
Last modified:March 3, 2009 - v1
Checksum:i3D3F7C55D300C99F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302050 mRNA Translation: BAH13618.1
RefSeqiXP_011535939.1, XM_011537637.2
UniGeneiHs.122926

Genome annotation databases

GeneIDi2908

Entry informationi

Entry nameiB7Z7I2_HUMAN
AccessioniPrimary (citable) accession number: B7Z7I2
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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