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B7Z7D2

- B7Z7D2_HUMAN

UniProt

B7Z7D2 - B7Z7D2_HUMAN

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Protein
Submitted name: Lysosomal acid phosphatase
Gene
ACP2
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. acid phosphatase activity Source: InterPro
Complete GO annotation...

GO - Biological processi

    Complete GO annotation...

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Lysosomal acid phosphataseImported
    Submitted name:
    cDNA FLJ51131, highly similar to Lysosomal acid phosphatase (EC 3.1.3.2)Imported
    Gene namesi
    Name:ACP2Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 11

    Organism-specific databases

    HGNCiHGNC:123. ACP2.

    Structurei

    3D structure databases

    ProteinModelPortaliB7Z7D2.
    SMRiB7Z7D2. Positions 36-338.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG002203.

    Family and domain databases

    Gene3Di3.40.50.1240. 1 hit.
    InterProiIPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view]
    PfamiPF00328. His_Phos_2. 1 hit.
    [Graphical view]
    SUPFAMiSSF53254. SSF53254. 1 hit.
    PROSITEiPS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7Z7D2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAGKRSGWSR AALLQLLLGV NLVVMPPTRA RSLRFVTLEG MLQHWELGQA    50
    LRQRYHGFLN TSYHRQEVYV RSTDFDRTLM SAEANLAGLF PPNGMQRFNP 100
    NISWQPIPVH TVPITEDRLL KFPLGPCPRY EQLQNETRQT PEYQNESSRN 150
    AQFLDMVANE TGLTDLTLET VWNVYDTLFC EQTHGLRLPP WASPQTMQRL 200
    SRLKDFSFRF LFGIYQQAEK ARLQGGVLLA QIRKNLTLMA TTSQLPKLLV 250
    YSAHDTTLVA LQMALDVYNG EQAPYASCHI FELYQEDSGN FSVEMYFRNE 300
    SDKAPWPLSL PGCPHRCPLQ DFLRLTEPVV PKDWQQECQL ASGPADTEVI 350
    VALAVCGSIL FLLIVLLLTV LFRMQAQPPG YRHVADGEDH A 391
    Length:391
    Mass (Da):44,511
    Last modified:March 3, 2009 - v1
    Checksum:iAAC4A82797E28E70
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC018410 Genomic DNA. No translation available.
    AK301860 mRNA. Translation: BAH13568.1.
    UniGeneiHs.532492.

    Genome annotation databases

    EnsembliENST00000527256; ENSP00000432205; ENSG00000134575.
    UCSCiuc010rhf.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC018410 Genomic DNA. No translation available.
    AK301860 mRNA. Translation: BAH13568.1 .
    UniGenei Hs.532492.

    3D structure databases

    ProteinModelPortali B7Z7D2.
    SMRi B7Z7D2. Positions 36-338.
    ModBasei Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000527256 ; ENSP00000432205 ; ENSG00000134575 .
    UCSCi uc010rhf.2. human.

    Organism-specific databases

    HGNCi HGNC:123. ACP2.
    GenAtlasi Search...

    Phylogenomic databases

    HOVERGENi HBG002203.

    Miscellaneous databases

    GenomeRNAii 53.
    NextBioi 35480202.

    Family and domain databases

    Gene3Di 3.40.50.1240. 1 hit.
    InterProi IPR000560. His_Pase_superF_clade-2.
    IPR029033. His_PPase_superfam.
    [Graphical view ]
    Pfami PF00328. His_Phos_2. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53254. SSF53254. 1 hit.
    PROSITEi PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    « Hide 'large scale' publications
    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    2. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: TestisImported.
    3. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.

    Entry informationi

    Entry nameiB7Z7D2_HUMAN
    AccessioniPrimary (citable) accession number: B7Z7D2
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: September 3, 2014
    This is version 37 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    External Data

    Dasty 3

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