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Protein
Submitted name:

cDNA FLJ53932, highly similar to NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial (EC 1.6.5.3)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

OxidoreductaseUniRule annotation

Keywords - Ligandi

NADUniRule annotation, UbiquinoneImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ53932, highly similar to NADH-ubiquinone oxidoreductase 49 kDa subunit, mitochondrial (EC 1.6.5.3)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA31519.

PTM / Processingi

Proteomic databases

PaxDbiB7Z792.
PeptideAtlasiB7Z792.
PRIDEiB7Z792.

Expressioni

Gene expression databases

BgeeiENSG00000158864.
GenevisibleiB7Z792. HS.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000356972.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini142 – 405Complex1_49kDaInterPro annotationAdd BLAST264

Sequence similaritiesi

Belongs to the complex I 49 kDa subunit family.UniRule annotation

Phylogenomic databases

eggNOGiKOG2870. Eukaryota.
COG0649. LUCA.
HOVERGENiHBG000760.

Family and domain databases

Gene3Di1.10.645.10. 2 hits.
HAMAPiMF_01358. NDH1_NuoD. 1 hit.
InterProiIPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view]
PfamiPF00346. Complex1_49kDa. 1 hit.
[Graphical view]
SUPFAMiSSF56762. SSF56762. 1 hit.
TIGRFAMsiTIGR01962. NuoD. 1 hit.
PROSITEiPS00535. COMPLEX1_49K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z792-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MYPSKETAHW KPPPWNDVDP PKDTIVKNIT LNFGPQHPAA HGVLRLVMEL
60 70 80 90 100
SGEMVRKCDP HIGLLHRGTE KLIEYKTYLQ ALPYFDRLDY VSMMCNEQAY
110 120 130 140 150
SLAVEKLLNI RPPPRAQWIR VLFGEITRLL NHIMAVTTHA LDLGAMTPFF
160 170 180 190 200
WLFEEREKMF EFYERVSGAR MHAAYIRPGG VHQDLPLGLM DDIYQFSKNF
210 220 230 240 250
SLRLDELEEL LTNNRIWRNR TIDIGVVTAE EALNYGFSGV MLRGSGIQWD
260 270 280 290 300
LRKTQPYDVY DQVEFDVPVG SRGDCYDRYL CRVEEMRQSL RIIAQCLNKM
310 320 330 340 350
PPGEIKVDDA KVSPPKRAEM KTSMESLIHH FKLYTEGYQV PPGATYTAIE
360 370 380 390 400
APKGEFGVYL VSDGSSRPYR CKIKAPGFAH LAGLDKMSKG HMLADVVAII

GTRPIV
Length:406
Mass (Da):46,397
Last modified:March 3, 2009 - v1
Checksum:iED7F2BDAC594DFC4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301641 mRNA. Translation: BAH13528.1.
RefSeqiNP_001159631.1. NM_001166159.1.
UniGeneiHs.173611.

Genome annotation databases

GeneIDi4720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301641 mRNA. Translation: BAH13528.1.
RefSeqiNP_001159631.1. NM_001166159.1.
UniGeneiHs.173611.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000356972.

Proteomic databases

PaxDbiB7Z792.
PeptideAtlasiB7Z792.
PRIDEiB7Z792.

Protocols and materials databases

DNASUi4720.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi4720.

Organism-specific databases

CTDi4720.
PharmGKBiPA31519.

Phylogenomic databases

eggNOGiKOG2870. Eukaryota.
COG0649. LUCA.
HOVERGENiHBG000760.

Miscellaneous databases

GenomeRNAii4720.

Gene expression databases

BgeeiENSG00000158864.
GenevisibleiB7Z792. HS.

Family and domain databases

Gene3Di1.10.645.10. 2 hits.
HAMAPiMF_01358. NDH1_NuoD. 1 hit.
InterProiIPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view]
PfamiPF00346. Complex1_49kDa. 1 hit.
[Graphical view]
SUPFAMiSSF56762. SSF56762. 1 hit.
TIGRFAMsiTIGR01962. NuoD. 1 hit.
PROSITEiPS00535. COMPLEX1_49K. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB7Z792_HUMAN
AccessioniPrimary (citable) accession number: B7Z792
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 7, 2016
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.