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Protein
Submitted name:

Tropomyosin 1 (Alpha), isoform CRA_i

Gene

TPM1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Tropomyosin 1 (Alpha), isoform CRA_iImported
Submitted name:
cDNA FLJ54760, highly similar to Rattus norvegicus tropomyosin 1, alpha (Tpm1), transcript variant 7, mRNAImported
Gene namesi
Name:TPM1Imported
ORF Names:hCG_33495Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

MaxQBiB7Z722.
PeptideAtlasiB7Z722.
PRIDEiB7Z722.

Interactioni

Protein-protein interaction databases

IntActiB7Z722. 1 interactor.
STRINGi9606.ENSP00000267996.

Structurei

3D structure databases

ProteinModelPortaliB7Z722.
SMRiB7Z722.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili7 – 237Sequence analysisAdd BLAST231

Sequence similaritiesi

Belongs to the tropomyosin family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1003. Eukaryota.
ENOG410XR5K. LUCA.
HOVERGENiHBG107404.

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z722-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGSSSLEAV RRKIRSLQEQ ADAAEERAGT LQRELDHERK LRETAEADVA
60 70 80 90 100
SLNRRIQLVE EELDRAQERL ATALQKLEEA EKAADESERG MKVIESRAQK
110 120 130 140 150
DEEKMEIQEI QLKEAKHIAE DADRKYEEVA RKLVIIESDL ERAEERAELS
160 170 180 190 200
EGKCAELEEE LKTVTNNLKS LEAQAEKYSQ KEDRYEEEIK VLSDKLKEAE
210 220 230 240
TRAEFAERSV TKLEKSIDDL EEKVAHAKEE NLSMHQMLDQ TLLELNNM
Length:248
Mass (Da):28,608
Last modified:March 3, 2009 - v1
Checksum:iA175BDD53107B563
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301319 mRNA. Translation: BAH13458.1.
CH471082 Genomic DNA. Translation: EAW77629.1.
RefSeqiNP_001288218.1. NM_001301289.1.
UniGeneiHs.133892.
Hs.602995.

Genome annotation databases

GeneIDi7168.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK301319 mRNA. Translation: BAH13458.1.
CH471082 Genomic DNA. Translation: EAW77629.1.
RefSeqiNP_001288218.1. NM_001301289.1.
UniGeneiHs.133892.
Hs.602995.

3D structure databases

ProteinModelPortaliB7Z722.
SMRiB7Z722.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiB7Z722. 1 interactor.
STRINGi9606.ENSP00000267996.

Proteomic databases

MaxQBiB7Z722.
PeptideAtlasiB7Z722.
PRIDEiB7Z722.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi7168.

Organism-specific databases

CTDi7168.

Phylogenomic databases

eggNOGiKOG1003. Eukaryota.
ENOG410XR5K. LUCA.
HOVERGENiHBG107404.

Miscellaneous databases

ChiTaRSiTPM1. human.
GenomeRNAii7168.

Family and domain databases

InterProiIPR000533. Tropomyosin.
[Graphical view]
PfamiPF00261. Tropomyosin. 1 hit.
[Graphical view]
PRINTSiPR00194. TROPOMYOSIN.
PROSITEiPS00326. TROPOMYOSIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB7Z722_HUMAN
AccessioniPrimary (citable) accession number: B7Z722
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: November 2, 2016
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.