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Protein
Submitted name:

Lysosomal acid phosphatase

Gene

ACP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Lysosomal acid phosphataseImported
Submitted name:
cDNA FLJ51107, highly similar to Lysosomal acid phosphatase (EC 3.1.3.2)Imported
Gene namesi
Name:ACP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 11

Organism-specific databases

EuPathDBiHostDB:ENSG00000134575.9
HGNCiHGNC:123 ACP2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000134575

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_501408566731 – 162Sequence analysisAdd BLAST132

Proteomic databases

MaxQBiB7Z6U3
PeptideAtlasiB7Z6U3
PRIDEiB7Z6U3

Expressioni

Gene expression databases

BgeeiENSG00000134575
ExpressionAtlasiB7Z6U3 baseline and differential

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3720 Eukaryota
ENOG410ZVBQ LUCA
GeneTreeiENSGT00530000062956
HOGENOMiHOG000198917
HOVERGENiHBG106194

Family and domain databases

CDDicd07061 HP_HAP_like, 1 hit
Gene3Di3.40.50.1240, 1 hit
InterProiView protein in InterPro
IPR033379 Acid_Pase_AS
IPR000560 His_Pase_clade-2
IPR029033 His_PPase_superfam
PfamiView protein in Pfam
PF00328 His_Phos_2, 1 hit
SUPFAMiSSF53254 SSF53254, 1 hit
PROSITEiView protein in PROSITE
PS00616 HIS_ACID_PHOSPHAT_1, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z6U3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKRSGWSR AALLQLLLGV NLVVMPPTRA RSLRFVTLLY RHGDRSPVKT
60 70 80 90 100
YPKDPYQEEE WPQGFGQLTK EGMLQHWELG QALRQRYHGF LNTSYHRQEV
110 120 130 140 150
YVRSTDFDRT LMSAEANLAG LFPPNGMQRF NPNISWQPIP VHTVPITEDR
160
QAQVTRTVEH SA
Length:162
Mass (Da):18,672
Last modified:March 3, 2009 - v1
Checksum:iB845D6E0C1DB2243
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018410 Genomic DNA No translation available.
AK300931 mRNA Translation: BAH13379.1
UniGeneiHs.532492

Genome annotation databases

EnsembliENST00000530453; ENSP00000434205; ENSG00000134575
UCSCiuc058bce.1 human

Similar proteinsi

Entry informationi

Entry nameiB7Z6U3_HUMAN
AccessioniPrimary (citable) accession number: B7Z6U3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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