B7Z6S9 (B7Z6S9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ56157, highly similar to Glucosylceramidase (EC 3.2.1.45) EMBL BAH13365.1
Organism	Homo sapiens (Human) EMBL BAH13365.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	621 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro lysosome organization Inferred from electronic annotation. Source: InterPro sphingolipid metabolic process Inferred from electronic annotation. Source: InterPro
Cellular_component	lysosome Inferred from electronic annotation. Source: InterPro
Molecular_function	glucosylceramidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7Z6S9 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: E93D9A5ECE05AB07	FASTA	621	68,761
	10 20 30 40 50 60 MSDRLFSNPG PAPTPQGCFS RGCGWSGCIL PSESYCAGPQ SPVPPRRLCR LRWDFVLPPV 70 80 90 100 110 120 GAAVSLRRRD SGTPVVFSSS NDPEGMEFSS PSREECPKPL SRVSIMAGSL TGLLLLQAVS 130 140 150 160 170 180 WASGARPCIP KSFGYSSVVC VCNATYCDSF DPPTFPALGT FSRYESTRSG RRMELSMGPI 190 200 210 220 230 240 QANHTGTGLL LTLQPEQKFQ KVKGFGGAMT DAAALNILAL SPPAQNLLLK SYFSEEGIGY 250 260 270 280 290 300 NIIRVPMASC DFSIRTYTYA DTPDDFQLHN FGLPEEDTKL KIPLIHRALQ LAQRPVSLLA 310 320 330 340 350 360 SPWTSPTWLK TNGAVNGKGS LKGQPGDIYH QTWARYFVKF LDAYAEHKLQ FWAVTAENEP 370 380 390 400 410 420 SAGLLSGYPF QCLGFTPEHQ RDFIARDLGP TLANSTHHNV RLLMLDDQRL LLPHWAKVVL 430 440 450 460 470 480 TDPEAAKYVH GIAVHWYLDF LAPAKATLGE THRLFPNTML FASEACVGSK FWEQSVRLGS 490 500 510 520 530 540 WDRGMQYSHS IITNLLYHVV GWTDWNLALN PEGGPNWVRN FVDSPIIVDI TKDTFYKQPM 550 560 570 580 590 600 FYHLGHFSKF IPEGSQRVGL VASQKNDLDA VALMHPDGSA VVVVLNRSSK DVPLTIKDPA 610 620 VGFLETISPG YSIHTYLWRR Q

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Small intestine EMBL BAH13365.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK300876 mRNA. Translation: BAH13365.1.
IPI	IPI00021807.
RefSeq	NP_001005741.1. NM_001005741.2. NP_001005742.1. NM_001005742.2. NP_001165282.1. NM_001171811.1.
UniGene	Hs.282997. Hs.719930.
3D structure databases
ProteinModelPortal	B7Z6S9.
ModBase	Search...
Protein-protein interaction databases
STRING	B7Z6S9.
Protein family/group databases
Allergome	8244. Hom s Glucocerebrosidase.
Proteomic databases
PRIDE	B7Z6S9.
Protocols and materials databases
DNASU	2629.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2629.
KEGG	hsa:2629.
Organism-specific databases
CTD	2629.
PharmGKB	PA28591.
Phylogenomic databases
HOGENOM	HOG000270031.
HOVERGEN	HBG002285.
KO	K01201.
Family and domain databases
Gene3D	2.60.40.1180. 1 hit. 3.20.20.80. 1 hit.
InterPro	IPR013780. Glyco_hydro_13_b. IPR001139. Glyco_hydro_30. IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
PANTHER	PTHR11069. PTHR11069. 1 hit.
Pfam	PF02055. Glyco_hydro_30. 1 hit. [Graphical view]
PRINTS	PR00843. GLHYDRLASE30.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...
Other
GenomeRNAi	2629.
NextBio	10357.

Entry information

Entry name

B7Z6S9_HUMAN

Accession

Primary (citable) accession number: B7Z6S9

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 31 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.