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Protein
Submitted name:

cDNA FLJ56152, highly similar to Rho guanine nucleotide exchange factor 7

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ56152, highly similar to Rho guanine nucleotide exchange factor 7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

MaxQBiB7Z6G2.
PRIDEiB7Z6G2.

Expressioni

Gene expression databases

BgeeiB7Z6G2.

Structurei

3D structure databases

ProteinModelPortaliB7Z6G2.
SMRiB7Z6G2. Positions 1-34, 48-475, 662-721.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains DH (DBL-homology) domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG050569.
KOiK13710.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR001715. CH-domain.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z6G2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTFDANDLY QGQNFNKVLS SLVTLNKVTA DIGLGSDSVC ARPSSHRIKS
60 70 80 90 100
FDSLGSQSLH TRTSKLFQGQ YRSLDMTDNS NNQLVVRAKF NFQQTNEDEL
110 120 130 140 150
SFSKGDVIHV TRVEEGGWWE GTLNGRTGWF PSNYVREVKA SEKPVSPKSG
160 170 180 190 200
TLKSPPKGFD TTAINKSYYN VVLQNILETE NEYSKELQTV LSTYLRPLQT
210 220 230 240 250
SEKLSSANIS YLMGNLEEIC SFQQMLVQSL EECTKLPEAQ QRVGGCFLNL
260 270 280 290 300
MPQMKTLYLT YCANHPSAVN VLTEHSEELG EFMETKGASS PGILVLTTGL
310 320 330 340 350
SKPFMRLDKY PTLLKELERH MEDYHTDRQD IQKSMAAFKN LSAQCQEVRK
360 370 380 390 400
RKELELQILT EAIRNWEGDD IKTLGNVTYM SQVLIQCAGS EEKNERYLLL
410 420 430 440 450
FPNVLLMLSA SPRMSGFIYQ GKLPTTGMTI TKLEDSENHR NAFEISGSMI
460 470 480 490 500
ERILVSCNNQ QDLQEWVEHL QKQTKVTSVG NPTIKPHSVP SHTLPSHPVT
510 520 530 540 550
PSSKHADSKP APLTPAYHTL PHPSHHGTPH TTINWGPLEP PKTPKPWSLS
560 570 580 590 600
CLRPAPPLRP SAALCYKEDL SKSPKTMKKL LPKRKPERKP SDEEFASRKS
610 620 630 640 650
TAALEEDAQI LKVIEAYCTS AKTRQTLNSS SRKESAPQVL LPEEEKIIVE
660 670 680 690 700
ETKSNGQTVI EEKSLVDTVY ALKDEVQELR QDNKKMKKSL EEEQRARKDL
710 720
EKLVRKVLKN MNDPAWDETN L
Length:721
Mass (Da):81,404
Last modified:March 3, 2009 - v1
Checksum:i4051F1413D21F0E2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300272 mRNA. Translation: BAH13248.1.
RefSeqiXP_005254148.1. XM_005254091.2.
UniGeneiHs.508738.

Genome annotation databases

GeneIDi8874.
KEGGihsa:8874.
UCSCiuc010tjo.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK300272 mRNA. Translation: BAH13248.1.
RefSeqiXP_005254148.1. XM_005254091.2.
UniGeneiHs.508738.

3D structure databases

ProteinModelPortaliB7Z6G2.
SMRiB7Z6G2. Positions 1-34, 48-475, 662-721.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB7Z6G2.
PRIDEiB7Z6G2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi8874.
KEGGihsa:8874.
UCSCiuc010tjo.2. human.

Organism-specific databases

CTDi8874.

Phylogenomic databases

HOVERGENiHBG050569.
KOiK13710.

Miscellaneous databases

ChiTaRSiARHGEF7. human.
GenomeRNAii8874.
NextBioi35479963.

Gene expression databases

BgeeiB7Z6G2.

Family and domain databases

Gene3Di1.10.418.10. 1 hit.
1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR001715. CH-domain.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR011511. SH3_2.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF07653. SH3_2. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: PlacentaImported.

Entry informationi

Entry nameiB7Z6G2_HUMAN
AccessioniPrimary (citable) accession number: B7Z6G2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 27, 2015
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.