ID   B7Z6F4_HUMAN            Unreviewed;       497 AA.
AC   B7Z6F4;
DT   03-MAR-2009, integrated into UniProtKB/TrEMBL.
DT   03-MAR-2009, sequence version 1.
DT   27-MAR-2024, entry version 55.
DE   RecName: Full=Chordin {ECO:0000256|ARBA:ARBA00016968};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606 {ECO:0000313|EMBL:BAH13240.1};
RN   [1] {ECO:0000313|EMBL:BAH13240.1}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Placenta {ECO:0000313|EMBL:BAH13240.1};
RA   Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A.,
RA   Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y.,
RA   Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.,
RA   Sugano S., Nomura N., Isogai T.;
RT   "NEDO human cDNA sequencing project focused on splicing variants.";
RL   Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; AK300213; BAH13240.1; -; mRNA.
DR   AlphaFoldDB; B7Z6F4; -.
DR   PeptideAtlas; B7Z6F4; -.
DR   ProteomicsDB; 6775; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR   Gene3D; 6.20.200.20; -; 1.
DR   InterPro; IPR010895; CHRD.
DR   InterPro; IPR001007; VWF_dom.
DR   PANTHER; PTHR46526; CHORDIN; 1.
DR   PANTHER; PTHR46526:SF1; CHORDIN; 1.
DR   Pfam; PF07452; CHRD; 2.
DR   Pfam; PF00093; VWC; 1.
DR   SMART; SM00754; CHRD; 2.
DR   SMART; SM00214; VWC; 3.
DR   SUPFAM; SSF57603; FnI-like domain; 3.
DR   PROSITE; PS50933; CHRD; 2.
DR   PROSITE; PS01208; VWFC_1; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein {ECO:0000256|ARBA:ARBA00022473, ECO:0000256|PROSITE-
KW   ProRule:PRU00230}; Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          32..154
FT                   /note="CHRD"
FT                   /evidence="ECO:0000259|PROSITE:PS50933"
FT   DOMAIN          160..280
FT                   /note="CHRD"
FT                   /evidence="ECO:0000259|PROSITE:PS50933"
FT   REGION          476..497
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   497 AA;  52790 MW;  5ACFB872739DDECE CRC64;
     MDWLVLGELQ MALEWAGRPG LRISGHIAAR KSCDVLQSVL CGADALIPVQ TGAAGSASLT
     LLGNGSLIYQ VQVVGTSSEV VAMTLETKPQ RRDQRTVLCH MAGLQPGGHT AVGICPGLGA
     RGAHMLLQNE LFLNVGTKDF PDGELRGHVA ALPYCGHSAR HDTLPVPLAG ALVLPPVKSQ
     AAGHAWLSLD THCHLHYEVL LAGLGGSEQG TVTAHLLGPP GTPGPRRLLK GFYGSEAQGV
     VKDLEPELLR HLAKGMASLM ITTKGSPRGE LRGQRRTVIC DPVVCPPPSC PHPVQAPDQC
     CPVCPEKQDV RDLPGLPRSR DPGEGCYFDG DRSWRAAGTR WHPVVPPFGL IKCAVCTCKG
     GTGEVHCEKV QCPRLACAQP VRVNPTDCCK QCPVGSGAHP QLGDPMQADG PRGCRFAGQW
     FPESQSWHPS VPPFGEMSCI TCRCGAGVPH CERDDCSLPL SCGSGKESRC CSRCTAHRRP
     APETRTDPEL EKEAEGS
//