B7Z6E6 (B7Z6E6_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Submitted name: cDNA FLJ51780, highly similar to Glucosylceramidase (EC 3.2.1.45) EMBL BAH13232.1
Organism	Homo sapiens (Human) EMBL BAH13232.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	521 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro sphingolipid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular_function	glucosylceramidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7Z6E6 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: AFE7FBC81EB406C9	FASTA	521	58,074
	10 20 30 40 50 60 MEFSSPSREE CPKPLSRVSV MAGSLTGLLL LQAVSWASGA RPCIPKSFGY SSVVCVCNAT 70 80 90 100 110 120 YCDSFDPPTF PALGTFSRYE STRSGRRMEL SMGPIQANHT GTGLLLTLQP DAAALNILAL 130 140 150 160 170 180 SPPAQNLLLK SYFSEEGIGY NIIRVPMASC DFSIRTYTYA DTPDDFQLHN FSLPEEDTKL 190 200 210 220 230 240 KIPLIHRALQ LAQRPVSLLA SPWTSPTWLK TNGAVNGKGS LKGQPGDIYH QTWARYFVKF 250 260 270 280 290 300 LDAYAEHKLQ FWAVTAENEP SAGLLSGYPF QCLGFTPEHQ RDFIARDLGP TLANSTHHNV 310 320 330 340 350 360 RLLMLDDQRL LLPHWAKVVL TDPEAAKYVH GIAVHWYLDF LAPAKATLGE THRLFPNTML 370 380 390 400 410 420 FASEACVGSK FWEQSVRLGS WDRGMQYSHS IITNLLYHVV GWTDWNLALN PEGGPNWVRN 430 440 450 460 470 480 FVDSPIIVDI TKDTFYKQPM FYHLGHFSKF IPEGSQRVGL VASQKNDLDA VALMHPDGSA 490 500 510 520 VVVVLNRPSK DVPLTIKDPA VGFLETISPG YSIHTYLWRR Q

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Placenta EMBL BAH13232.1.

+

Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK300186 mRNA. Translation: BAH13232.1.
IPI	IPI00021807.
UniGene	Hs.282997.
3D structure databases
ProteinModelPortal	B7Z6E6.
ModBase	Search...
Protein family/group databases
Allergome	8244. Hom s Glucocerebrosidase.
Proteomic databases
PRIDE	B7Z6E6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG002285.
Family and domain databases
Gene3D	2.60.40.1180. 1 hit. 3.20.20.80. 1 hit.
InterPro	IPR013780. Glyco_hydro_13_b. IPR001139. Glyco_hydro_30. IPR013781. Glyco_hydro_catalytic_dom. IPR017853. Glycoside_hydrolase_SF. [Graphical view]
PANTHER	PTHR11069. PTHR11069. 1 hit.
Pfam	PF02055. Glyco_hydro_30. 1 hit. [Graphical view]
PRINTS	PR00843. GLHYDRLASE30.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit.
ProtoNet	Search...
Other
NextBio	35479950.

Entry information

Entry name

B7Z6E6_HUMAN

Accession

Primary (citable) accession number: B7Z6E6

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 29, 2013
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.