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Protein
Submitted name:

Ankyrin-2

Gene

ANK2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Ankyrin-2Imported
Submitted name:
cDNA FLJ61595, highly similar to Ankyrin-2Imported
Gene namesi
Name:ANK2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 4

Organism-specific databases

EuPathDBiHostDB:ENSG00000145362.17
HGNCiHGNC:493 ANK2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000145362

PTM / Processingi

Proteomic databases

MaxQBiB7Z651
PeptideAtlasiB7Z651
PRIDEiB7Z651

Expressioni

Gene expression databases

BgeeiENSG00000145362
ExpressionAtlasiB7Z651 baseline and differential

Structurei

3D structure databases

SMRiB7Z651
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini9 – 792ANK_REP_REGIONInterPro annotationAdd BLAST784
Repeati42 – 74ANKPROSITE-ProRule annotationAdd BLAST33
Repeati75 – 107ANKPROSITE-ProRule annotationAdd BLAST33
Repeati108 – 140ANKPROSITE-ProRule annotationAdd BLAST33
Repeati211 – 243ANKPROSITE-ProRule annotationAdd BLAST33
Repeati244 – 276ANKPROSITE-ProRule annotationAdd BLAST33
Repeati277 – 309ANKPROSITE-ProRule annotationAdd BLAST33
Repeati310 – 342ANKPROSITE-ProRule annotationAdd BLAST33
Repeati343 – 375ANKPROSITE-ProRule annotationAdd BLAST33
Repeati376 – 408ANKPROSITE-ProRule annotationAdd BLAST33
Repeati409 – 441ANKPROSITE-ProRule annotationAdd BLAST33
Repeati442 – 474ANKPROSITE-ProRule annotationAdd BLAST33
Repeati475 – 507ANKPROSITE-ProRule annotationAdd BLAST33
Repeati508 – 540ANKPROSITE-ProRule annotationAdd BLAST33
Repeati541 – 573ANKPROSITE-ProRule annotationAdd BLAST33
Repeati574 – 606ANKPROSITE-ProRule annotationAdd BLAST33
Repeati607 – 639ANKPROSITE-ProRule annotationAdd BLAST33
Repeati640 – 672ANKPROSITE-ProRule annotationAdd BLAST33
Repeati673 – 705ANKPROSITE-ProRule annotationAdd BLAST33
Repeati706 – 738ANKPROSITE-ProRule annotationAdd BLAST33
Repeati739 – 771ANKPROSITE-ProRule annotationAdd BLAST33
Domaini947 – 1105ZU5InterPro annotationAdd BLAST159

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4177 Eukaryota
COG0666 LUCA
GeneTreeiENSGT00840000129677
HOGENOMiHOG000012873
HOVERGENiHBG004234

Family and domain databases

CDDicd00204 ANK, 6 hits
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR000906 ZU5_dom
PfamiView protein in Pfam
PF00023 Ank, 1 hit
PF12796 Ank_2, 8 hits
PF00791 ZU5, 2 hits
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 23 hits
SM00218 ZU5, 1 hit
SUPFAMiSSF48403 SSF48403, 3 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 20 hits
PS51145 ZU5, 1 hit

Sequencei

Sequence statusi: Fragment.

B7Z651-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTTMLQKSDS NASFLRAARA GNLDKVVEYL KGGIDINTCN QNGLNALHLA
60 70 80 90 100
AKEGHVGLVQ ELLGRGSSVD SATKKGNTAL HIASLAGQAE VVKVLVKEGA
110 120 130 140 150
NINAQSQNGF TPLYMAAQEN HIDVVKYLLE NGANQSTATE DGFTPLAVAL
160 170 180 190 200
QQGHNQAVAI LLENDTKGKV RLPALHIAAR KDDTKSAALL LQNDHNADVQ
210 220 230 240 250
SKMMVNRTTE SGFTPLHIAA HYGNVNVATL LLNRGAAVDF TARNGITPLH
260 270 280 290 300
VASKRGNTNM VKLLLDRGGQ IDAKTRDGLT PLHCAARSGH DQVVELLLER
310 320 330 340 350
GAPLLARTKN GLSPLHMAAQ GDHVECVKHL LQHKAPVDDV TLDYLTALHV
360 370 380 390 400
AAHCGHYRVT KLLLDKRANP NARALNGFTP LHIACKKNRI KVMELLVKYG
410 420 430 440 450
ASIQAITESG LTPIHVAAFM GHLNIVLLLL QNGASPDVTN IRGETALHMA
460 470 480 490 500
ARAGQVEVVR CLLRNGALVD ARAREEQTPL HIASRLGKTE IVQLLLQHMA
510 520 530 540 550
HPDAATTNGY TPLHISAREG QVDVASVLLE AGAAHSLATK KGFTPLHVAA
560 570 580 590 600
KYGSLDVAKL LLQRRAAADS AGKNGLTPLH VAAHYDNQKV ALLLLEKGAS
610 620 630 640 650
PHATAKNGYT PLHIAAKKNQ MQIASTLLNY GAETNIVTKQ GVTPLHLASQ
660 670 680 690 700
EGHTDMVTLL LDKGANIHMS TKSGLTSLHL AAQEDKVNVA DILTKHGADQ
710 720 730 740 750
DAHTKLGYTP LIVACHYGNV KMVNFLLKQG ANVNAKTKNG YTPLHQAAQQ
760 770 780 790 800
GHTHIINVLL QHGAKPNATT ANGNTALAIA KRLGYISVVD TLKVVTEEVT
810 820 830 840 850
TTTTTITEKH KLNVPETMTE VLDVSDEEGD DTMTGDGGEY LRPEDLKELG
860 870 880 890 900
DDSLPSSQFL DGMNYLRYSL EGGRSDSLRS FSSDRSHTLS HASYLRDSAV
910 920 930 940 950
MDDSVVIPSH QVSTLAKEAE RNSYRLSWGT ENLDNVALSS SPIHSGFLVS
960 970 980 990 1000
FMVDARGGAM RGCRHNGLRI IIPPRKCTAP TRVTCRLVKR HRLATMPPMV
1010 1020 1030 1040 1050
EGEGLASRLI EVGPSGAQFL GKLHLPTAPP PLNEGESLVS RILQLGPPGT
1060 1070 1080 1090 1100
KFLGPVIVEI PHFAALRGKE RELVVLRSEN GDSWKEHFCD YTEDELNEIL
1110
NGMDEVLDSP EDLE
Length:1,114
Mass (Da):119,906
Last modified:March 3, 2009 - v1
Checksum:iB2B47487854727F2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1114Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC004057 Genomic DNA No translation available.
AC017007 Genomic DNA No translation available.
AC093617 Genomic DNA No translation available.
AC093879 Genomic DNA No translation available.
AC093900 Genomic DNA No translation available.
AC108042 Genomic DNA No translation available.
AK299815 mRNA Translation: BAH13137.1
UniGeneiHs.620557

Genome annotation databases

EnsembliENST00000503271; ENSP00000423799; ENSG00000145362
UCSCiuc062zcx.1 human

Similar proteinsi

Entry informationi

Entry nameiB7Z651_HUMAN
AccessioniPrimary (citable) accession number: B7Z651
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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