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Protein
Submitted name:

Heterogeneous nuclear ribonucleoprotein Q

Gene

SYNCRIP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionRibonucleoproteinImported, RNA-bindingPROSITE-ProRule annotation, Viral nucleoproteinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Heterogeneous nuclear ribonucleoprotein QImported
Submitted name:
Synaptotagmin binding, cytoplasmic RNA interacting protein, isoform CRA_bImported
Submitted name:
cDNA FLJ50849, highly similar to Heterogeneous nuclear ribonucleoprotein QImported
Gene namesi
Name:SYNCRIPImported
ORF Names:hCG_401112Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

EuPathDBiHostDB:ENSG00000135316.17
HGNCiHGNC:16918 SYNCRIP

Subcellular locationi

Keywords - Cellular componenti

Virion

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000135316
PharmGKBiPA134985065

PTM / Processingi

Proteomic databases

MaxQBiB7Z645
PeptideAtlasiB7Z645

Expressioni

Gene expression databases

BgeeiENSG00000135316

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 143RRMInterPro annotationAdd BLAST80
Domaini145 – 227RRMInterPro annotationAdd BLAST83
Domaini240 – 310RRMInterPro annotationAdd BLAST71

Phylogenomic databases

eggNOGiKOG0117 Eukaryota
ENOG410XTJ5 LUCA
GeneTreeiENSGT00550000074366
HOVERGENiHBG051917

Family and domain databases

CDDicd12483 RRM1_hnRNPQ, 1 hit
cd12489 RRM2_hnRNPQ, 1 hit
Gene3Di3.30.70.330, 3 hits
InterProiView protein in InterPro
IPR006535 HnRNP_R/Q_splicing_fac
IPR034544 hnRNPQ_RRM1
IPR034548 hnRNPQ_RRM2
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
PfamiView protein in Pfam
PF00076 RRM_1, 3 hits
SMARTiView protein in SMART
SM00360 RRM, 3 hits
SUPFAMiSSF54928 SSF54928, 3 hits
TIGRFAMsiTIGR01648 hnRNP-R-Q, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 3 hits

Sequencei

Sequence statusi: Complete.

B7Z645-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKTYRQREKQ GTKVADSSKG PDEAKIKALL ERTGYTLDVT TGQRKYGGPP
60 70 80 90 100
PDSVYSGQQP SVGTEIFVGK IPRDLFEDEL VPLFEKAGPI WDLRLMMDPL
110 120 130 140 150
TGLNRGYAFV TFCTKEAAQE AVKLYNNHEI RSGKHIGVCI SVANNRLFVG
160 170 180 190 200
SIPKSKTKEQ ILEEFSKVTE GLTDVILYHQ PDDKKKNRGF CFLEYEDHKT
210 220 230 240 250
AAQARRRLMS GKVKVWGNVG TVEWADPIED PDPEVMAKVK VLFVRNLANT
260 270 280 290 300
VTEEILEKAF SQFGKLERVK KLKDYAFIHF DERDGAVKAM EEMNGKDLEG
310 320 330 340 350
ENIEIVFAKP PDQKRKERKA QRQAAKNQMY DDYYYYGPPH MPPPTRGRGR
360 370 380 390 400
GGRGGYGYPP DYYGYEDYYD YYGYDYHNYR GGYEDPYYGY EDFQVGARGR
410 420 430 440 450
GGRGARGAAP SRGRGAAPPR GRAGYSQRGG PGSARGVRGA RGGAQQQRGR
460
GQGKGVEAGP DLLQ
Length:464
Mass (Da):52,047
Last modified:March 3, 2009 - v1
Checksum:i4A0ED156A86D27CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136082 Genomic DNA No translation available.
AK299796 mRNA Translation: BAH13131.1
CH471051 Genomic DNA Translation: EAW48623.1
RefSeqiNP_001153145.1, NM_001159673.1
UniGeneiHs.571177

Genome annotation databases

EnsembliENST00000616122; ENSP00000484577; ENSG00000135316
GeneIDi10492
UCSCiuc003pky.4 human

Similar proteinsi

Entry informationi

Entry nameiB7Z645_HUMAN
AccessioniPrimary (citable) accession number: B7Z645
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 25, 2018
This is version 74 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health