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Protein
Submitted name:

cDNA FLJ52440, highly similar to Lysosomal acid phosphatase (EC 3.1.3.2)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52440, highly similar to Lysosomal acid phosphatase (EC 3.1.3.2)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei318 – 341HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_500286396331 – 360Sequence analysisAdd BLAST330

Proteomic databases

PaxDbiB7Z4Z2.
PeptideAtlasiB7Z4Z2.
PRIDEiB7Z4Z2.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000256997.

Structurei

3D structure databases

ProteinModelPortaliB7Z4Z2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the histidine acid phosphatase family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3720. Eukaryota.
ENOG410ZVBQ. LUCA.
HOVERGENiHBG002203.

Family and domain databases

CDDicd07061. HP_HAP_like. 1 hit.
Gene3Di3.40.50.1240. 2 hits.
InterProiIPR033379. Acid_Pase_AS.
IPR000560. His_Pase_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 2 hits.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z4Z2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGKRSGWSR AALLQLLLGV NLVVMPPTRA RSLRFVTLLY RHGDRSPVKT
60 70 80 90 100
CPKDPYQEEE WPQGFGQLTK EGMLQHWELG QALRQRYHGF LNTSYHRQEV
110 120 130 140 150
YVRSTDFDRT LMSAEANLAG LFPPNGMQRF NPNISWQPIP VHTVPITEDR
160 170 180 190 200
QTHGLRLPPW ASPQTMQRLS RLKDFSFRFL FGIYQQAEKA RLQGGVLLAQ
210 220 230 240 250
IRKNLTLMAT TSQLPKLLVY SAHDTTLVAL QMALDVYNGE QAPYASCHIF
260 270 280 290 300
ELYQEDSGNF SVEMYFRNES DKAPWPLSLP GCPHRCPLQD FLRLTEPVVP
310 320 330 340 350
KDWQQECQLA SGPADTEVIV ALAVCGSILF LLIVLLLTVL FRMQAQPPGY
360
RHVADGEDHA
Length:360
Mass (Da):40,930
Last modified:March 3, 2009 - v1
Checksum:i6848BFFAF674359F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK298122 mRNA. Translation: BAH12728.1.
RefSeqiNP_001289420.1. NM_001302491.1.
UniGeneiHs.532492.

Genome annotation databases

GeneIDi53.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK298122 mRNA. Translation: BAH12728.1.
RefSeqiNP_001289420.1. NM_001302491.1.
UniGeneiHs.532492.

3D structure databases

ProteinModelPortaliB7Z4Z2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000256997.

Proteomic databases

PaxDbiB7Z4Z2.
PeptideAtlasiB7Z4Z2.
PRIDEiB7Z4Z2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi53.

Organism-specific databases

CTDi53.

Phylogenomic databases

eggNOGiKOG3720. Eukaryota.
ENOG410ZVBQ. LUCA.
HOVERGENiHBG002203.

Miscellaneous databases

GenomeRNAii53.

Family and domain databases

CDDicd07061. HP_HAP_like. 1 hit.
Gene3Di3.40.50.1240. 2 hits.
InterProiIPR033379. Acid_Pase_AS.
IPR000560. His_Pase_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 2 hits.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiB7Z4Z2_HUMAN
AccessioniPrimary (citable) accession number: B7Z4Z2
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: September 7, 2016
This is version 28 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.