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B7Z4N8 (B7Z4N8_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein attributes

Sequence length483 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Catalytic activity

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). RuleBase RU004435

Sequence similarities

Belongs to the peptidase C19 family. RuleBase RU004434

Contains USP domain. SAAS SAAS001394

Ontologies

Keywords
   Biological processUbl conjugation pathway RuleBase RU004434
   Molecular functionHydrolase
Protease
Thiol protease RuleBase RU004434
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processubiquitin-dependent protein catabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from direct assay. Source: HPA

   Molecular_functioncysteine-type peptidase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
B7Z4N8 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: B57991EE5A5CCA4E

FASTA48354,770
        10         20         30         40         50         60 
MPLYSVTVKW GKEKFEGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMVKG GTLKGMTLLM 

        70         80         90        100        110        120 
MGSADALPEE PSAKTVFVED MTEEQLASAM ELPCGLTNLG NTCYMNATVQ CIRSVPELKD 

       130        140        150        160        170        180 
ALKRYAGALR ASGEMASAQY ITAALRDLFD SMDKTSSSIP PIILLQFLHM AFPQFAEKGE 

       190        200        210        220        230        240 
QGQYLQQDAN ECWIQMMRVL QQKLEAIEDD SVKETDSSSA SAATPSKKKS LIDQFFGVEF 

       250        260        270        280        290        300 
ETTMKCTESE EEEVTKGKEN QLQLSCFINQ EVKYLFTGLK LRLQEEITKQ SPTLQRNALY 

       310        320        330        340        350        360 
IKSSKISRLP AYLTIQMVRF FYKEKESVNA KVLKDVKFPL MLDMYELCTP ELQEKMVSFR 

       370        380        390        400        410        420 
SKFKDLEDKK VNQQPNTSDK KSSPQKEVKY EPFSFADDIG SNNCGYYDLQ AVLTHQGRSS 

       430        440        450        460        470        480 
SSGHYVSWVK RKQDEWIKFD DDKVSIVTPE DILRLSGGGD WHIAYVLLYG PRRVEIMEEE 


SEQ 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP000845 Genomic DNA. No translation available.
AK297605 mRNA. Translation: BAH12624.1.
UniGeneHs.464416.
Hs.707058.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000400266; ENSP00000383125; ENSG00000101557.
KEGGhsa:9097.
UCSCuc010wyr.1. human.

Organism-specific databases

CTD9097.
HGNCHGNC:12612. USP14.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG054185.
KOK11843.

Family and domain databases

InterProIPR018200. Pept_C19ubi-hydrolase_C_CS.
IPR001394. Peptidase_C19_UCH.
IPR000626. Ubiquitin-like.
IPR028889. UCH/PAN2.
[Graphical view]
PfamPF00443. UCH. 1 hit.
[Graphical view]
SMARTSM00213. UBQ. 1 hit.
[Graphical view]
PROSITEPS00972. UCH_2_1. 1 hit.
PS00973. UCH_2_2. 1 hit.
PS50235. UCH_2_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

GenomeRNAi9097.
NextBio35479520.

Entry information

Entry nameB7Z4N8_HUMAN
AccessionPrimary (citable) accession number: B7Z4N8
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 16, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.