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Protein
Submitted name:

Syntaxin 4A (Placental), isoform CRA_a

Gene

STX4A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Syntaxin 4A (Placental), isoform CRA_aImported
Submitted name:
cDNA FLJ57517, highly similar to Syntaxin-4Imported
Gene namesi
Name:STX4AImported
ORF Names:hCG_21149Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei196 – 218HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB7Z425.
PRIDEiB7Z425.

Expressioni

Gene expression databases

BgeeiENSG00000103496.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000317714.

Structurei

3D structure databases

ProteinModelPortaliB7Z425.
SMRiB7Z425.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini122 – 184T-SNARE coiled-coil homologyInterPro annotationAdd BLAST63

Sequence similaritiesi

Belongs to the syntaxin family.SAAS annotation

Keywords - Domaini

Coiled coilSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG0810. Eukaryota.
COG5074. LUCA.
HOGENOMiHOG000286023.
HOVERGENiHBG000497.

Family and domain databases

InterProiView protein in InterPro
IPR010989. SNARE.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR000727. T_SNARE_dom.
PfamiView protein in Pfam
PF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
SMARTiView protein in SMART
SM00397. t_SNARE. 1 hit.
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiView protein in PROSITE
PS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z425-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKQELQNLRD EIKQLGREIR LQLKAIEPQK EEADENYNSV NTRMRKTQHG
60 70 80 90 100
VLSQQFVELI NKCNSMQSEY REKNVERIRR QLKITNAGMV SDEELEQMLD
110 120 130 140 150
SGQSEVFVSN ILKDTQVTRQ ALNEISARHS EIQQLERSIR ELHDIFTFLA
160 170 180 190 200
TEVEMQGEMI NRIEKNILSS ADYVERGQEH VKTALENQKK ARKKKVLIAI
210
CVSITVVLLA VIIGVTVVG
Length:219
Mass (Da):25,262
Last modified:March 3, 2009 - v1
Checksum:i4062706AB6A41D45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296652 mRNA. Translation: BAH12411.1.
CH471192 Genomic DNA. Translation: EAW52175.1.
RefSeqiNP_001259024.1. NM_001272095.1.
UniGeneiHs.83734.

Genome annotation databases

GeneIDi6810.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296652 mRNA. Translation: BAH12411.1.
CH471192 Genomic DNA. Translation: EAW52175.1.
RefSeqiNP_001259024.1. NM_001272095.1.
UniGeneiHs.83734.

3D structure databases

ProteinModelPortaliB7Z425.
SMRiB7Z425.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000317714.

Proteomic databases

PeptideAtlasiB7Z425.
PRIDEiB7Z425.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6810.

Organism-specific databases

CTDi6810.

Phylogenomic databases

eggNOGiKOG0810. Eukaryota.
COG5074. LUCA.
HOGENOMiHOG000286023.
HOVERGENiHBG000497.

Miscellaneous databases

ChiTaRSiSTX4. human.
GenomeRNAii6810.

Gene expression databases

BgeeiENSG00000103496.

Family and domain databases

InterProiView protein in InterPro
IPR010989. SNARE.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR000727. T_SNARE_dom.
PfamiView protein in Pfam
PF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
SMARTiView protein in SMART
SM00397. t_SNARE. 1 hit.
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiView protein in PROSITE
PS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiB7Z425_HUMAN
AccessioniPrimary (citable) accession number: B7Z425
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: February 15, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.