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B7Z418 (B7Z418_HUMAN) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

cDNA FLJ50979, moderately similar to Integrin-linked protein kinase (EC 2.7.11.1) EMBL BAH12404.1
Gene names
Name:ILK Ensembl ENSP00000435323
OrganismHomo sapiens (Human) [Reference proteome] EMBL BAH12404.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Protein attributes

Sequence length391 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 2 ANK repeats. RuleBase RU003321

Sequences

Sequence LengthMass (Da)Tools
B7Z418 [UniParc].

Last modified March 3, 2009. Version 1.
Checksum: 3290120580572F3C

FASTA39144,349
        10         20         30         40         50         60 
MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI 

        70         80         90        100        110        120 
NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAESGQ 

       130        140        150        160        170        180 
RRWARISTVF HTRTHSGRGP PALGPLWKGR WQGNDIVVKV LKVRDWSTRK SRDFNEECPR 

       190        200        210        220        230        240 
LRIFSHPNVL PVLGACQSPP APHPTLITHW MPYGSLYNVL HEGTNFVVDQ SQAVKFALDM 

       250        260        270        280        290        300 
ARGMAFLHTL EPLIPRHALN SRSVMIDEDM TARISMADVK FSFQCPGRMY APAWVAPEAL 

       310        320        330        340        350        360 
QKKPEDTNRR SADMWSFAVL LWELVTREVP FADLSNMEIG MKVALEGLRP TIPPGISPHV 

       370        380        390 
CKLMKICMNE DPAKRPKFDM IVPILEKMQD K 

« Hide

References

« Hide 'large scale' references
[1]"Human chromosome 11 DNA sequence and analysis including novel gene identification."
Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. expand/collapse author list , Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y.
Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]"NEDO human cDNA sequencing project focused on splicing variants."
Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. expand/collapse author list , Sugano S., Nomura N., Isogai T.
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Colon EMBL BAH12404.1.
[3]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC091564 Genomic DNA. No translation available.
AK296628 mRNA. Translation: BAH12404.1.
RefSeqNP_001265370.1. NM_001278441.1.
UniGeneHs.706355.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENST00000528995; ENSP00000435323; ENSG00000166333.
GeneID3611.
KEGGhsa:3611.
UCSCuc010raq.2. human.

Organism-specific databases

CTD3611.
HGNCHGNC:6040. ILK.
GenAtlasSearch...

Phylogenomic databases

HOVERGENHBG002437.
KOK06272.

Family and domain databases

Gene3D1.25.40.20. 1 hit.
InterProIPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR001245. Ser-Thr/Tyr_kinase_cat_dom.
[Graphical view]
PfamPF00023. Ank. 1 hit.
PF12796. Ank_2. 1 hit.
PF07714. Pkinase_Tyr. 1 hit.
[Graphical view]
SMARTSM00248. ANK. 2 hits.
[Graphical view]
SUPFAMSSF48403. SSF48403. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 2 hits.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSILK. human.
GenomeRNAi3611.
NextBio35479365.

Entry information

Entry nameB7Z418_HUMAN
AccessionPrimary (citable) accession number: B7Z418
Entry history
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: April 16, 2014
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.