B7Z418 (B7Z418_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Integrin-linked protein kinase Ensembl ENSP00000435323

Submitted name:
cDNA FLJ50979, moderately similar to Integrin-linked protein kinase (EC 2.7.11.1) EMBL BAH12404.1

Gene names

Name:

ILK Ensembl ENSP00000435323

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAH12404.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	391 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Domain	ANK repeat RuleBase RU003321 Repeat RuleBase RU003536
Molecular function	Integrin EMBL BAH12404.1 Kinase EMBL BAH12404.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	integrin-mediated signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: InterPro protein kinase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7Z418 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 3290120580572F3C	FASTA	391	44,349
	10 20 30 40 50 60 MDDIFTQCRE GNAVAVRLWL DNTENDLNQG DDHGFSPLHW ACREGRSAVV EMLIMRGARI 70 80 90 100 110 120 NVMNRGDDTP LHLAASHGHR DIVQKLLQYK ADINAVNEHG NVPLHYACFW GQDQVAESGQ 130 140 150 160 170 180 RRWARISTVF HTRTHSGRGP PALGPLWKGR WQGNDIVVKV LKVRDWSTRK SRDFNEECPR 190 200 210 220 230 240 LRIFSHPNVL PVLGACQSPP APHPTLITHW MPYGSLYNVL HEGTNFVVDQ SQAVKFALDM 250 260 270 280 290 300 ARGMAFLHTL EPLIPRHALN SRSVMIDEDM TARISMADVK FSFQCPGRMY APAWVAPEAL 310 320 330 340 350 360 QKKPEDTNRR SADMWSFAVL LWELVTREVP FADLSNMEIG MKVALEGLRP TIPPGISPHV 370 380 390 CKLMKICMNE DPAKRPKFDM IVPILEKMQD K

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Human chromosome 11 DNA sequence and analysis including novel gene identification." Taylor T.D., Noguchi H., Totoki Y., Toyoda A., Kuroki Y., Dewar K., Lloyd C., Itoh T., Takeda T., Kim D.W., She X., Barlow K.F., Bloom T., Bruford E., Chang J.L., Cuomo C.A., Eichler E., FitzGerald M.G. , Jaffe D.B., LaButti K., Nicol R., Park H.S., Seaman C., Sougnez C., Yang X., Zimmer A.R., Zody M.C., Birren B.W., Nusbaum C., Fujiyama A., Hattori M., Rogers J., Lander E.S., Sakaki Y. Nature 440:497-500(2006) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Colon EMBL BAH12404.1.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC091564 Genomic DNA. No translation available. AK296628 mRNA. Translation: BAH12404.1.
IPI	IPI00922759.
UniGene	Hs.706355.
3D structure databases
SMR	B7Z418. Positions 1-117, 144-391.
ModBase	Search...
Proteomic databases
PRIDE	B7Z418.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000528995; ENSP00000435323; ENSG00000166333.
UCSC	uc010raq.2. human.
Organism-specific databases
HGNC	HGNC:6040. ILK.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG002437.
Gene expression databases
ArrayExpress	B7Z418.
Family and domain databases
Gene3D	1.25.40.20. 1 hit.
InterPro	IPR002110. Ankyrin_rpt. IPR020683. Ankyrin_rpt-contain_dom. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR001245. Ser-Thr/Tyr_kinase_cat_dom. [Graphical view]
Pfam	PF12796. Ank_2. 2 hits. PF07714. Pkinase_Tyr. 1 hit. [Graphical view]
SMART	SM00248. ANK. 2 hits. [Graphical view]
SUPFAM	SSF48403. ANK. 1 hit. SSF56112. Kinase_like. 1 hit.
PROSITE	PS50297. ANK_REP_REGION. 1 hit. PS50088. ANK_REPEAT. 2 hits. PS50011. PROTEIN_KINASE_DOM. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	ILK. human.
NextBio	35479365.

Entry information

Entry name

B7Z418_HUMAN

Accession

Primary (citable) accession number: B7Z418

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.