Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

40S ribosomal protein S3a

Gene

RPS3A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May play a role during erythropoiesis through regulation of transcription factor DDIT3.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal proteinUniRule annotationSAAS annotationImported
Biological processDifferentiationUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S3aUniRule annotation
Gene namesi
Name:RPS3AUniRule annotation
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation, NucleusUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedUniRule annotation

Proteomic databases

PeptideAtlasiB7Z3M5
PRIDEiB7Z3M5

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (28S, 5.8S and 5S). Identified in a IGF2BP1-dependent mRNP granule complex containing untranslated mRNAs. Binds with high affinity to IPO4. Interacts with DDIT3.UniRule annotation

Protein-protein interaction databases

IntActiB7Z3M5, 1 interactor
MINTiB7Z3M5

Family & Domainsi

Sequence similaritiesi

Belongs to the eukaryotic ribosomal protein eS1 family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1628 Eukaryota
COG1890 LUCA
HOGENOMiHOG000105220
HOVERGENiHBG000783

Family and domain databases

HAMAPiMF_03122 Ribosomal_S3Ae_euk, 1 hit
InterProiView protein in InterPro
IPR027500 Ribosomal_S1/3_euk
IPR001593 Ribosomal_S3Ae
IPR018281 Ribosomal_S3Ae_CS
PfamiView protein in Pfam
PF01015 Ribosomal_S3Ae, 1 hit
SMARTiView protein in SMART
SM01397 Ribosomal_S3Ae, 1 hit
PROSITEiView protein in PROSITE
PS01191 RIBOSOMAL_S3AE, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

B7Z3M5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVGKKKVVD PFSKKDWYDV KAPAMFNIRN IGKTLVTRTQ GTKIASDGLK
60 70 80 90 100
GRVFEVSLAD LQNDEVAFRK FKLITEDVQG KNCLTNFHGM DLTRDKMCSM
110 120 130 140 150
VKKWQTMIEA HVDVKTTDGY LLRLFCVGFT KKRNNQIRKT SYAQHQQVRQ
160 170
IRKKMMEIMT REVQTNDLKE VVNKL
Length:175
Mass (Da):20,294
Last modified:March 3, 2009 - v1
Checksum:iAF5A0F35604E6E5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK296121 mRNA Translation: BAH12261.1
RefSeqiNP_001254628.1, NM_001267699.1
UniGeneiHs.356572

Genome annotation databases

GeneIDi6189

Similar proteinsi

Entry informationi

Entry nameiB7Z3M5_HUMAN
AccessioniPrimary (citable) accession number: B7Z3M5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: March 28, 2018
This is version 52 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health