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B7Z3C7

- B7Z3C7_HUMAN

UniProt

B7Z3C7 - B7Z3C7_HUMAN

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Protein
Submitted name:

cDNA FLJ50776, highly similar to Rho guanine nucleotide exchange factor 6

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. Rho guanyl-nucleotide exchange factor activity Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50776, highly similar to Rho guanine nucleotide exchange factor 6Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Structurei

3D structure databases

ProteinModelPortaliB7Z3C7.
SMRiB7Z3C7. Positions 7-425, 584-635.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains DH (DBL-homology) domain.SAAS annotation
Contains PH domain.SAAS annotation

Phylogenomic databases

HOVERGENiHBG050569.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR000219. DH-domain.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEiPS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z3C7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTENGSHQLI VKARFNFKQT NEDELSVCKG DIIYVTRVEE GGWWEGTLNG
60 70 80 90 100
RTGWFPSNYV REIKSSDGVS LLLPGLECNG AISAHHNLCL PGSKRPLSPK
110 120 130 140 150
AVKGFETAPL TKNYYTVVLQ NILDTEKEYA KELQSLLVTY LRPLQSNNNL
160 170 180 190 200
STVEVTSLLG NFEEVCTFQQ TLCQALEECS KFPENQHKVG GCLLSLMPHF
210 220 230 240 250
KSMYLAYCAN HPSAVNVLTQ HSDELEQFME NQGASSPGIL ILTTNLSKPF
260 270 280 290 300
MRLEKYVTLL QELERHMEDT HPDHQDILKA IVAFKTLMGQ CQDLRKRKQL
310 320 330 340 350
ELQILSEPIQ AWEGEDIKNL GNVIFMSQVM VQYGACEEKE ERYLMLFSNV
360 370 380 390 400
LIMLSASPRM SGFIYQGKIP IAGTVVTRLD EIEGNDCTFE ITGNTVERIV
410 420 430 440 450
VHCNNNQDFQ EWLEQLNRLI RGPASCSSLS KTSSSSCSAH SSFSSTGQPR
460 470 480 490 500
GPLEPPQIIK PWSLSCLRPA PPLRPSAALG YKERMSYILK ESSKSPKTMK
510 520 530 540 550
KFLHKRKTER KPSEEEYVIR KSTAALEEDA QILKVIEAYC TSANFQQGHG
560 570 580 590 600
SSTRKDSIPQ VLLPEEEKLI IEETRSNGQT IMEEKSLVDT VYALKDEVRE
610 620 630 640
LKQENKRMKQ CLEEELKSRR DLEKLVRRLL KQTDECIRGE SSSKTSILP
Length:649
Mass (Da):73,460
Last modified:March 3, 2009 - v1
Checksum:i48C2C78045328090
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295709 mRNA. Translation: BAH12163.1.
UniGeneiHs.522795.

Genome annotation databases

UCSCiuc011mwd.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295709 mRNA. Translation: BAH12163.1 .
UniGenei Hs.522795.

3D structure databases

ProteinModelPortali B7Z3C7.
SMRi B7Z3C7. Positions 7-425, 584-635.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc011mwd.2. human.

Phylogenomic databases

HOVERGENi HBG050569.

Miscellaneous databases

ChiTaRSi ARHGEF6. human.
NextBioi 35479208.

Family and domain databases

Gene3Di 1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProi IPR000219. DH-domain.
IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
[Graphical view ]
Pfami PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view ]
PRINTSi PR00452. SH3DOMAIN.
SMARTi SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF48065. SSF48065. 1 hit.
SSF50044. SSF50044. 1 hit.
PROSITEi PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HippocampusImported.

Entry informationi

Entry nameiB7Z3C7_HUMAN
AccessioniPrimary (citable) accession number: B7Z3C7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.