Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

B7Z3C7

- B7Z3C7_HUMAN

UniProt

B7Z3C7 - B7Z3C7_HUMAN

Protein
Submitted name:

cDNA FLJ50776, highly similar to Rho guanine nucleotide exchange factor 6

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 46 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    GO - Molecular functioni

    1. Rho guanyl-nucleotide exchange factor activity Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ50776, highly similar to Rho guanine nucleotide exchange factor 6Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Family & Domainsi

    Sequence similaritiesi

    Contains DH (DBL-homology) domain.SAAS annotation
    Contains PH domain.SAAS annotation

    Phylogenomic databases

    HOVERGENiHBG050569.

    Family and domain databases

    Gene3Di1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    InterProiIPR000219. DH-domain.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR001452. SH3_domain.
    [Graphical view]
    PfamiPF00169. PH. 1 hit.
    PF00621. RhoGEF. 1 hit.
    PF14604. SH3_9. 1 hit.
    [Graphical view]
    PRINTSiPR00452. SH3DOMAIN.
    SMARTiSM00233. PH. 1 hit.
    SM00325. RhoGEF. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF48065. SSF48065. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEiPS50010. DH_2. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7Z3C7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTENGSHQLI VKARFNFKQT NEDELSVCKG DIIYVTRVEE GGWWEGTLNG    50
    RTGWFPSNYV REIKSSDGVS LLLPGLECNG AISAHHNLCL PGSKRPLSPK 100
    AVKGFETAPL TKNYYTVVLQ NILDTEKEYA KELQSLLVTY LRPLQSNNNL 150
    STVEVTSLLG NFEEVCTFQQ TLCQALEECS KFPENQHKVG GCLLSLMPHF 200
    KSMYLAYCAN HPSAVNVLTQ HSDELEQFME NQGASSPGIL ILTTNLSKPF 250
    MRLEKYVTLL QELERHMEDT HPDHQDILKA IVAFKTLMGQ CQDLRKRKQL 300
    ELQILSEPIQ AWEGEDIKNL GNVIFMSQVM VQYGACEEKE ERYLMLFSNV 350
    LIMLSASPRM SGFIYQGKIP IAGTVVTRLD EIEGNDCTFE ITGNTVERIV 400
    VHCNNNQDFQ EWLEQLNRLI RGPASCSSLS KTSSSSCSAH SSFSSTGQPR 450
    GPLEPPQIIK PWSLSCLRPA PPLRPSAALG YKERMSYILK ESSKSPKTMK 500
    KFLHKRKTER KPSEEEYVIR KSTAALEEDA QILKVIEAYC TSANFQQGHG 550
    SSTRKDSIPQ VLLPEEEKLI IEETRSNGQT IMEEKSLVDT VYALKDEVRE 600
    LKQENKRMKQ CLEEELKSRR DLEKLVRRLL KQTDECIRGE SSSKTSILP 649
    Length:649
    Mass (Da):73,460
    Last modified:March 3, 2009 - v1
    Checksum:i48C2C78045328090
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK295709 mRNA. Translation: BAH12163.1.
    UniGeneiHs.522795.

    Genome annotation databases

    UCSCiuc011mwd.2. human.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK295709 mRNA. Translation: BAH12163.1 .
    UniGenei Hs.522795.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    UCSCi uc011mwd.2. human.

    Phylogenomic databases

    HOVERGENi HBG050569.

    Miscellaneous databases

    ChiTaRSi ARHGEF6. human.
    NextBioi 35479208.

    Family and domain databases

    Gene3Di 1.20.900.10. 1 hit.
    2.30.29.30. 1 hit.
    InterProi IPR000219. DH-domain.
    IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR001452. SH3_domain.
    [Graphical view ]
    Pfami PF00169. PH. 1 hit.
    PF00621. RhoGEF. 1 hit.
    PF14604. SH3_9. 1 hit.
    [Graphical view ]
    PRINTSi PR00452. SH3DOMAIN.
    SMARTi SM00233. PH. 1 hit.
    SM00325. RhoGEF. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48065. SSF48065. 1 hit.
    SSF50044. SSF50044. 1 hit.
    PROSITEi PS50010. DH_2. 1 hit.
    PS50003. PH_DOMAIN. 1 hit.
    PS50002. SH3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: HippocampusImported.
    2. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiB7Z3C7_HUMAN
    AccessioniPrimary (citable) accession number: B7Z3C7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 46 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.