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Protein
Submitted name:

cDNA FLJ57116, highly similar to Sodium- and chloride-dependent GABA transporter 1

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Biological processSymportSAAS annotation, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ57116, highly similar to Sodium- and chloride-dependent GABA transporter 1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei32 – 51HelicalSequence analysisAdd BLAST20
Transmembranei63 – 86HelicalSequence analysisAdd BLAST24
Transmembranei106 – 131HelicalSequence analysisAdd BLAST26
Transmembranei143 – 168HelicalSequence analysisAdd BLAST26
Transmembranei202 – 223HelicalSequence analysisAdd BLAST22
Transmembranei244 – 269HelicalSequence analysisAdd BLAST26
Transmembranei275 – 299HelicalSequence analysisAdd BLAST25
Transmembranei320 – 339HelicalSequence analysisAdd BLAST20
Transmembranei359 – 379HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiB7Z3C5
PRIDEiB7Z3C5

Structurei

3D structure databases

ProteinModelPortaliB7Z3C5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3659 Eukaryota
COG0733 LUCA
HOVERGENiHBG071421

Family and domain databases

InterProiView protein in InterPro
IPR000175 Na/ntran_symport
IPR002980 Na/ntran_symport_GABA_GAT1
IPR037272 SNS_sf
PANTHERiPTHR11616 PTHR11616, 1 hit
PfamiView protein in Pfam
PF00209 SNF, 1 hit
PRINTSiPR01195 GAT1TRNSPORT
PR00176 NANEUSMPORT
SUPFAMiSSF161070 SSF161070, 1 hit
PROSITEiView protein in PROSITE
PS50267 NA_NEUROTRAN_SYMP_3, 1 hit

Sequencei

Sequence statusi: Complete.

B7Z3C5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNTTNMTSA VVEFWERNMH QMTDGLDKPG QIRWPLAITL AIAWILVYFC
60 70 80 90 100
IWKGVGWTGK VVYFSATYPY IMLIILFFRG VTLPGAKEGI LFYITPNFRK
110 120 130 140 150
LSDSEVWLDA ATQIFFSYGL GLGSLIALGS YNSFHNNVYR DSIIVCCINS
160 170 180 190 200
CTSMFAGFVI FSIVGFMAHV TKRSIADVAA SGPGLAFLAY PEAVTQLPIS
210 220 230 240 250
PLWAILFFSM LLMLGIDSQF CTVEGFITAL VDEYPRLLRN RRELFIAAVC
260 270 280 290 300
IISYLIGLSN ITQGGIYVFK LFDYYSASGM SLLFLVFFEC VSISWFYGVN
310 320 330 340 350
RFYDNIQEMV GSRPCIWWKL CWSFFTPIIV AGVFIFSAVQ MTPLTMGNYV
360 370 380 390 400
FPKWGQGVGW LMALSSMVLI PGYMAYMFLT LKGSLKQRIQ VMVQPSEDIV
410 420
RPENGPEQPQ AGSSTSKEAY I
Length:421
Mass (Da):47,350
Last modified:March 3, 2009 - v1
Checksum:iBE1D3CF21B988F59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295702 mRNA Translation: BAH12161.1
RefSeqiNP_001335181.1, NM_001348252.1
NP_001335182.1, NM_001348253.1
UniGeneiHs.443874

Genome annotation databases

GeneIDi6529

Similar proteinsi

Entry informationi

Entry nameiB7Z3C5_HUMAN
AccessioniPrimary (citable) accession number: B7Z3C5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: May 23, 2018
This is version 67 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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