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Protein

Transporter

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

SymportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
TransporterUniRule annotation
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei32 – 5120HelicalSequence analysisAdd
BLAST
Transmembranei63 – 8624HelicalSequence analysisAdd
BLAST
Transmembranei106 – 13126HelicalSequence analysisAdd
BLAST
Transmembranei143 – 16826HelicalSequence analysisAdd
BLAST
Transmembranei202 – 22322HelicalSequence analysisAdd
BLAST
Transmembranei244 – 26926HelicalSequence analysisAdd
BLAST
Transmembranei275 – 29925HelicalSequence analysisAdd
BLAST
Transmembranei320 – 33920HelicalSequence analysisAdd
BLAST
Transmembranei359 – 37921HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiB7Z3C5.
PeptideAtlasiB7Z3C5.

Expressioni

Gene expression databases

BgeeiB7Z3C5.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000287766.

Structurei

3D structure databases

ProteinModelPortaliB7Z3C5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3659. Eukaryota.
COG0733. LUCA.
HOVERGENiHBG071421.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
IPR002980. Na/ntran_symport_GABA_GAT1.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR01195. GAT1TRNSPORT.
PR00176. NANEUSMPORT.
PROSITEiPS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z3C5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNTTNMTSA VVEFWERNMH QMTDGLDKPG QIRWPLAITL AIAWILVYFC
60 70 80 90 100
IWKGVGWTGK VVYFSATYPY IMLIILFFRG VTLPGAKEGI LFYITPNFRK
110 120 130 140 150
LSDSEVWLDA ATQIFFSYGL GLGSLIALGS YNSFHNNVYR DSIIVCCINS
160 170 180 190 200
CTSMFAGFVI FSIVGFMAHV TKRSIADVAA SGPGLAFLAY PEAVTQLPIS
210 220 230 240 250
PLWAILFFSM LLMLGIDSQF CTVEGFITAL VDEYPRLLRN RRELFIAAVC
260 270 280 290 300
IISYLIGLSN ITQGGIYVFK LFDYYSASGM SLLFLVFFEC VSISWFYGVN
310 320 330 340 350
RFYDNIQEMV GSRPCIWWKL CWSFFTPIIV AGVFIFSAVQ MTPLTMGNYV
360 370 380 390 400
FPKWGQGVGW LMALSSMVLI PGYMAYMFLT LKGSLKQRIQ VMVQPSEDIV
410 420
RPENGPEQPQ AGSSTSKEAY I
Length:421
Mass (Da):47,350
Last modified:March 3, 2009 - v1
Checksum:iBE1D3CF21B988F59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295702 mRNA. Translation: BAH12161.1.
UniGeneiHs.443874.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295702 mRNA. Translation: BAH12161.1.
UniGeneiHs.443874.

3D structure databases

ProteinModelPortaliB7Z3C5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000287766.

Proteomic databases

PaxDbiB7Z3C5.
PeptideAtlasiB7Z3C5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG3659. Eukaryota.
COG0733. LUCA.
HOVERGENiHBG071421.

Miscellaneous databases

ChiTaRSiSLC6A1. human.

Gene expression databases

BgeeiB7Z3C5.

Family and domain databases

InterProiIPR000175. Na/ntran_symport.
IPR002980. Na/ntran_symport_GABA_GAT1.
[Graphical view]
PANTHERiPTHR11616. PTHR11616. 1 hit.
PfamiPF00209. SNF. 1 hit.
[Graphical view]
PRINTSiPR01195. GAT1TRNSPORT.
PR00176. NANEUSMPORT.
PROSITEiPS50267. NA_NEUROTRAN_SYMP_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HippocampusImported.

Entry informationi

Entry nameiB7Z3C5_HUMAN
AccessioniPrimary (citable) accession number: B7Z3C5
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 6, 2016
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.