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B7Z353

- B7Z353_HUMAN

UniProt

B7Z353 - B7Z353_HUMAN

Protein

Serine/threonine-protein phosphatase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    [a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro
    2. iron ion binding Source: InterPro
    3. manganese ion binding Source: InterPro
    4. phosphoprotein phosphatase activity Source: UniProtKB-EC

    GO - Biological processi

    1. detection of stimulus involved in sensory perception Source: InterPro

    Keywords - Molecular functioni

    HydrolaseUniRule annotation

    Keywords - Ligandi

    CalciumUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Expressioni

    Gene expression databases

    ArrayExpressiB7Z353.
    BgeeiB7Z353.

    Structurei

    3D structure databases

    ProteinModelPortaliB7Z353.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the PPP phosphatase family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG008238.

    Family and domain databases

    Gene3Di1.10.238.10. 1 hit.
    3.60.21.10. 2 hits.
    InterProiIPR004843. Calcineurin-like_PHP_apaH.
    IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR029052. Metallo-depent_PP-like.
    IPR013235. PPP_dom.
    IPR012008. Ser/Thr-Pase_EF-hand_contain.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view]
    PfamiPF13499. EF-hand_7. 1 hit.
    PF00149. Metallophos. 1 hit.
    PF08321. PPP5. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000912. PPEF. 1 hit.
    PRINTSiPR00114. STPHPHTASE.
    SMARTiSM00054. EFh. 3 hits.
    SM00156. PP2Ac. 1 hit.
    [Graphical view]
    SUPFAMiSSF56300. SSF56300. 2 hits.
    PROSITEiPS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 3 hits.
    PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7Z353-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQLSTFFSFM LENYTHIHKE ELELRNQSLE SEQDMRDRWD YVDSIDVPDS    50
    YNGPRLQFPL TCTDIDLLLE AFKEQQILHA HYVLEVLFET KKVLKQMPNF 100
    THIQTSPSKE VTICGDLHGK LDDLFLIFYK NGLPSERNPY VFNGDFVDRG 150
    KNSIEILMIL CVSFLVYPND LHLNRGNHED FMMNLRYGFT KEILHKYKLH 200
    GKRILQILEE FYAWLPIGTI VDNEILVIHG GISETTDLNL LHRVERNKMK 250
    SVLIPPTETN RDHDTDSKHN KVGVTFNAHG RIKTNGSPTE HLTEHEWEQI 300
    IDILWSDPRG KNGCFPNTCR GGGCYFGPDV TSKILNKYQL KMLIRSHECK 350
    PEGYEICHDG KVVTIFSASN YYEEGSNRGA YIKLCSGTTP RFFQYQVTKA 400
    TCFQPLRQRV DTMENSAIKI LRERVISRKS DLTRAFQLQD HRKSGKLSVS 450
    QWAFCMENIL GLNLPWRSLS SNLVNIDQNG NVEYMSSFQN IRIEKPVQEA 500
    HSTLVETLYR YRSDLEIIFN AIDTDHSGLI SVEEFRAMWK LFSSHYNVHI 550
    DDSQVNKLAN IMDLNKDGSI DFNEFLKAFY VVHRYEDLMK PDVTNLG 597
    Length:597
    Mass (Da):69,353
    Last modified:March 3, 2009 - v1
    Checksum:iED756F263ADFE77A
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK295504 mRNA. Translation: BAH12089.1.
    UniGeneiHs.211589.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK295504 mRNA. Translation: BAH12089.1 .
    UniGenei Hs.211589.

    3D structure databases

    ProteinModelPortali B7Z353.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Phylogenomic databases

    HOVERGENi HBG008238.

    Miscellaneous databases

    NextBioi 35479150.

    Gene expression databases

    ArrayExpressi B7Z353.
    Bgeei B7Z353.

    Family and domain databases

    Gene3Di 1.10.238.10. 1 hit.
    3.60.21.10. 2 hits.
    InterProi IPR004843. Calcineurin-like_PHP_apaH.
    IPR011992. EF-hand-dom_pair.
    IPR018247. EF_Hand_1_Ca_BS.
    IPR002048. EF_hand_dom.
    IPR029052. Metallo-depent_PP-like.
    IPR013235. PPP_dom.
    IPR012008. Ser/Thr-Pase_EF-hand_contain.
    IPR006186. Ser/Thr-sp_prot-phosphatase.
    [Graphical view ]
    Pfami PF13499. EF-hand_7. 1 hit.
    PF00149. Metallophos. 1 hit.
    PF08321. PPP5. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000912. PPEF. 1 hit.
    PRINTSi PR00114. STPHPHTASE.
    SMARTi SM00054. EFh. 3 hits.
    SM00156. PP2Ac. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56300. SSF56300. 2 hits.
    PROSITEi PS00018. EF_HAND_1. 2 hits.
    PS50222. EF_HAND_2. 3 hits.
    PS00125. SER_THR_PHOSPHATASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: HippocampusImported.

    Entry informationi

    Entry nameiB7Z353_HUMAN
    AccessioniPrimary (citable) accession number: B7Z353
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.