B7Z353 (B7Z353_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names	Recommended name: Serine/threonine-protein phosphatase RuleBase RU004273 EC=3.1.3.16 RuleBase RU004273
Organism	Homo sapiens (Human) EMBL BAH12089.1
Taxonomic identifier	9606 [NCBI]
Taxonomic lineage	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	597 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	A phosphoprotein + H2O = a protein + phosphate. RuleBase RU004273
Sequence similarities	Belongs to the PPP phosphatase family. RuleBase RU004273

Ontologies

Keywords
Ligand	Calcium RuleBase RU000331 Iron RuleBase RU004273
Molecular function	Hydrolase RuleBase RU004273
Gene Ontology (GO)
Biological_process	detection of stimulus involved in sensory perception Inferred from electronic annotation. Source: InterPro
Molecular_function	calcium ion binding Inferred from electronic annotation. Source: InterPro iron ion binding Inferred from electronic annotation. Source: InterPro manganese ion binding Inferred from electronic annotation. Source: InterPro phosphoprotein phosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7Z353 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: ED756F263ADFE77A	FASTA	597	69,353
	10 20 30 40 50 60 MQLSTFFSFM LENYTHIHKE ELELRNQSLE SEQDMRDRWD YVDSIDVPDS YNGPRLQFPL 70 80 90 100 110 120 TCTDIDLLLE AFKEQQILHA HYVLEVLFET KKVLKQMPNF THIQTSPSKE VTICGDLHGK 130 140 150 160 170 180 LDDLFLIFYK NGLPSERNPY VFNGDFVDRG KNSIEILMIL CVSFLVYPND LHLNRGNHED 190 200 210 220 230 240 FMMNLRYGFT KEILHKYKLH GKRILQILEE FYAWLPIGTI VDNEILVIHG GISETTDLNL 250 260 270 280 290 300 LHRVERNKMK SVLIPPTETN RDHDTDSKHN KVGVTFNAHG RIKTNGSPTE HLTEHEWEQI 310 320 330 340 350 360 IDILWSDPRG KNGCFPNTCR GGGCYFGPDV TSKILNKYQL KMLIRSHECK PEGYEICHDG 370 380 390 400 410 420 KVVTIFSASN YYEEGSNRGA YIKLCSGTTP RFFQYQVTKA TCFQPLRQRV DTMENSAIKI 430 440 450 460 470 480 LRERVISRKS DLTRAFQLQD HRKSGKLSVS QWAFCMENIL GLNLPWRSLS SNLVNIDQNG 490 500 510 520 530 540 NVEYMSSFQN IRIEKPVQEA HSTLVETLYR YRSDLEIIFN AIDTDHSGLI SVEEFRAMWK 550 560 570 580 590 LFSSHYNVHI DDSQVNKLAN IMDLNKDGSI DFNEFLKAFY VVHRYEDLMK PDVTNLG

References

[1]

"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Hippocampus EMBL BAH12089.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK295504 mRNA. Translation: BAH12089.1.
IPI	IPI00513950.
UniGene	Hs.211589.
3D structure databases
ProteinModelPortal	B7Z353.
ModBase	Search...
Protein-protein interaction databases
STRING	B7Z353.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
HOVERGEN	HBG008238.
Gene expression databases
ArrayExpress	B7Z353.
Bgee	B7Z353.
Family and domain databases
Gene3D	1.10.238.10. 1 hit.
InterPro	IPR011992. EF-hand-like_dom. IPR018247. EF_Hand_1_Ca_BS. IPR002048. EF_hand_dom. IPR004843. Metallo_PEstase_dom. IPR013235. PPP_dom. IPR012008. Ser/Thr-Pase_EF-hand_contain. IPR006186. Ser/Thr-sp_prot-phosphatase. [Graphical view]
Pfam	PF13499. EF_hand_5. 1 hit. PF00149. Metallophos. 1 hit. PF08321. PPP5. 1 hit. [Graphical view]
PIRSF	PIRSF000912. PPEF. 1 hit.
PRINTS	PR00114. STPHPHTASE.
SMART	SM00054. EFh. 3 hits. SM00156. PP2Ac. 1 hit. [Graphical view]
PROSITE	PS00018. EF_HAND_1. 2 hits. PS50222. EF_HAND_2. 3 hits. PS00125. SER_THR_PHOSPHATASE. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35479150.

Entry information

Entry name

B7Z353_HUMAN

Accession

Primary (citable) accession number: B7Z353

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.