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B7Z353

- B7Z353_HUMAN

UniProt

B7Z353 - B7Z353_HUMAN

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Protein
Serine/threonine-protein phosphatase
Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.UniRule annotation

GO - Molecular functioni

  1. calcium ion binding Source: InterPro
  2. iron ion binding Source: InterPro
  3. manganese ion binding Source: InterPro
  4. phosphoprotein phosphatase activity Source: UniProtKB-EC

GO - Biological processi

  1. detection of stimulus involved in sensory perception Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Ligandi

CalciumUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein phosphataseUniRule annotation (EC:3.1.3.16UniRule annotation)
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Expressioni

Gene expression databases

ArrayExpressiB7Z353.
BgeeiB7Z353.

Structurei

3D structure databases

ProteinModelPortaliB7Z353.

Family & Domainsi

Sequence similaritiesi

Belongs to the PPP phosphatase family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG008238.

Family and domain databases

Gene3Di1.10.238.10. 1 hit.
3.60.21.10. 2 hits.
InterProiIPR004843. Calcineurin-like_PHP_apaH.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR012008. Ser/Thr-Pase_EF-hand_contain.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view]
PfamiPF13499. EF-hand_7. 1 hit.
PF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
[Graphical view]
PIRSFiPIRSF000912. PPEF. 1 hit.
PRINTSiPR00114. STPHPHTASE.
SMARTiSM00054. EFh. 3 hits.
SM00156. PP2Ac. 1 hit.
[Graphical view]
SUPFAMiSSF56300. SSF56300. 2 hits.
PROSITEiPS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z353-1 [UniParc]FASTAAdd to Basket

« Hide

MQLSTFFSFM LENYTHIHKE ELELRNQSLE SEQDMRDRWD YVDSIDVPDS    50
YNGPRLQFPL TCTDIDLLLE AFKEQQILHA HYVLEVLFET KKVLKQMPNF 100
THIQTSPSKE VTICGDLHGK LDDLFLIFYK NGLPSERNPY VFNGDFVDRG 150
KNSIEILMIL CVSFLVYPND LHLNRGNHED FMMNLRYGFT KEILHKYKLH 200
GKRILQILEE FYAWLPIGTI VDNEILVIHG GISETTDLNL LHRVERNKMK 250
SVLIPPTETN RDHDTDSKHN KVGVTFNAHG RIKTNGSPTE HLTEHEWEQI 300
IDILWSDPRG KNGCFPNTCR GGGCYFGPDV TSKILNKYQL KMLIRSHECK 350
PEGYEICHDG KVVTIFSASN YYEEGSNRGA YIKLCSGTTP RFFQYQVTKA 400
TCFQPLRQRV DTMENSAIKI LRERVISRKS DLTRAFQLQD HRKSGKLSVS 450
QWAFCMENIL GLNLPWRSLS SNLVNIDQNG NVEYMSSFQN IRIEKPVQEA 500
HSTLVETLYR YRSDLEIIFN AIDTDHSGLI SVEEFRAMWK LFSSHYNVHI 550
DDSQVNKLAN IMDLNKDGSI DFNEFLKAFY VVHRYEDLMK PDVTNLG 597
Length:597
Mass (Da):69,353
Last modified:March 3, 2009 - v1
Checksum:iED756F263ADFE77A
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK295504 mRNA. Translation: BAH12089.1.
UniGeneiHs.211589.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK295504 mRNA. Translation: BAH12089.1 .
UniGenei Hs.211589.

3D structure databases

ProteinModelPortali B7Z353.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Phylogenomic databases

HOVERGENi HBG008238.

Miscellaneous databases

NextBioi 35479150.

Gene expression databases

ArrayExpressi B7Z353.
Bgeei B7Z353.

Family and domain databases

Gene3Di 1.10.238.10. 1 hit.
3.60.21.10. 2 hits.
InterProi IPR004843. Calcineurin-like_PHP_apaH.
IPR011992. EF-hand-dom_pair.
IPR018247. EF_Hand_1_Ca_BS.
IPR002048. EF_hand_dom.
IPR029052. Metallo-depent_PP-like.
IPR013235. PPP_dom.
IPR012008. Ser/Thr-Pase_EF-hand_contain.
IPR006186. Ser/Thr-sp_prot-phosphatase.
[Graphical view ]
Pfami PF13499. EF-hand_7. 1 hit.
PF00149. Metallophos. 1 hit.
PF08321. PPP5. 1 hit.
[Graphical view ]
PIRSFi PIRSF000912. PPEF. 1 hit.
PRINTSi PR00114. STPHPHTASE.
SMARTi SM00054. EFh. 3 hits.
SM00156. PP2Ac. 1 hit.
[Graphical view ]
SUPFAMi SSF56300. SSF56300. 2 hits.
PROSITEi PS00018. EF_HAND_1. 2 hits.
PS50222. EF_HAND_2. 3 hits.
PS00125. SER_THR_PHOSPHATASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: HippocampusImported.

Entry informationi

Entry nameiB7Z353_HUMAN
AccessioniPrimary (citable) accession number: B7Z353
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 9, 2014
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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