Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

B7Z313

- B7Z313_HUMAN

UniProt

B7Z313 - B7Z313_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

cDNA FLJ50525, highly similar to Amyloid beta A4 protein (APP) (ABPP) (Alzheimer disease amyloid protein homolog)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. DNA binding Source: Ensembl
  2. peptidase activator activity Source: Ensembl

GO - Biological processi

  1. adult locomotory behavior Source: Ensembl
  2. axon cargo transport Source: Ensembl
  3. axon midline choice point recognition Source: Ensembl
  4. cellular copper ion homeostasis Source: Ensembl
  5. cholesterol metabolic process Source: Ensembl
  6. collateral sprouting in absence of injury Source: Ensembl
  7. dendrite development Source: Ensembl
  8. endocytosis Source: Ensembl
  9. extracellular matrix organization Source: Ensembl
  10. forebrain development Source: Ensembl
  11. ionotropic glutamate receptor signaling pathway Source: Ensembl
  12. mating behavior Source: Ensembl
  13. mRNA polyadenylation Source: Ensembl
  14. negative regulation of neuron differentiation Source: Ensembl
  15. neuromuscular process controlling balance Source: Ensembl
  16. neuron apoptotic process Source: Ensembl
  17. neuron remodeling Source: Ensembl
  18. positive regulation of G2/M transition of mitotic cell cycle Source: Ensembl
  19. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  20. protein phosphorylation Source: Ensembl
  21. regulation of epidermal growth factor-activated receptor activity Source: Ensembl
  22. regulation of multicellular organism growth Source: Ensembl
  23. regulation of protein binding Source: Ensembl
  24. regulation of synapse structure and activity Source: Ensembl
  25. regulation of translation Source: Ensembl
  26. response to oxidative stress Source: Ensembl
  27. smooth endoplasmic reticulum calcium ion homeostasis Source: Ensembl
  28. suckling behavior Source: Ensembl
  29. synaptic growth at neuromuscular junction Source: Ensembl
  30. visual learning Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50525, highly similar to Amyloid beta A4 protein (APP) (ABPP) (Alzheimer disease amyloid protein homolog)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. apical part of cell Source: Ensembl
  2. axon Source: Ensembl
  3. cell-cell junction Source: Ensembl
  4. ciliary rootlet Source: Ensembl
  5. ER to Golgi transport vesicle Source: Ensembl
  6. Golgi apparatus Source: Ensembl
  7. integral component of membrane Source: Ensembl
  8. neuromuscular junction Source: Ensembl
  9. perinuclear region of cytoplasm Source: Ensembl
  10. plasma membrane Source: Ensembl
  11. spindle midzone Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB7Z313.

Expressioni

Gene expression databases

BgeeiB7Z313.
ExpressionAtlasiB7Z313. baseline and differential.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000232190.
HOVERGENiHBG000051.

Family and domain databases

Gene3Di4.10.230.10. 1 hit.
InterProiIPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR024329. Amyloid_glyco_E2_domain.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
[Graphical view]
PANTHERiPTHR23103:SF7. PTHR23103:SF7. 1 hit.
PfamiPF10515. APP_amyloid. 1 hit.
PF12925. APP_E2. 1 hit.
PF03494. Beta-APP. 1 hit.
[Graphical view]
PRINTSiPR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
SUPFAMiSSF109843. SSF109843. 1 hit.
PROSITEiPS00320. A4_INTRA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z313-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLKKYVRAEQ KDRQHTLKHF EHVRMVDPKK AAQIRSQVMT HLRVIYERMN
60 70 80 90 100
QSLSLLYNVP AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA
110 120 130 140 150
LMPSLTETKT TVELLPVNGE FSLDDLQPWH SFGADSVPAN TENEVEPVDA
160 170 180 190 200
RPAADRGLTT RPGSGLTNIK TEEISEVKMD AEFRHDSGYE VHHQKLVFFA
210 220 230 240 250
EDVGSNKGAI IGLMVGGVVI ATVIVITLVM LKKKQYTSIH HGVVEVDAAV
260 270
TPEERHLSKM QQNGYENPTY KFFEQMQN
Length:278
Mass (Da):31,450
Last modified:March 3, 2009 - v1
Checksum:i0E42419A05F5387E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK295373 mRNA. Translation: BAH12049.1.
UniGeneiHs.434980.

Genome annotation databases

UCSCiuc011acg.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK295373 mRNA. Translation: BAH12049.1 .
UniGenei Hs.434980.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi B7Z313.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

UCSCi uc011acg.2. human.

Phylogenomic databases

HOGENOMi HOG000232190.
HOVERGENi HBG000051.

Miscellaneous databases

NextBioi 35479126.

Gene expression databases

Bgeei B7Z313.
ExpressionAtlasi B7Z313. baseline and differential.

Family and domain databases

Gene3Di 4.10.230.10. 1 hit.
InterProi IPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR024329. Amyloid_glyco_E2_domain.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
[Graphical view ]
PANTHERi PTHR23103:SF7. PTHR23103:SF7. 1 hit.
Pfami PF10515. APP_amyloid. 1 hit.
PF12925. APP_E2. 1 hit.
PF03494. Beta-APP. 1 hit.
[Graphical view ]
PRINTSi PR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
SUPFAMi SSF109843. SSF109843. 1 hit.
PROSITEi PS00320. A4_INTRA. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Corpus callosumImported.

Entry informationi

Entry nameiB7Z313_HUMAN
AccessioniPrimary (citable) accession number: B7Z313
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.