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Protein
Submitted name:

cDNA FLJ50525, highly similar to Amyloid beta A4 protein (APP) (ABPP) (Alzheimer disease amyloid protein homolog)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ50525, highly similar to Amyloid beta A4 protein (APP) (ABPP) (Alzheimer disease amyloid protein homolog)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiB7Z313.

Expressioni

Gene expression databases

BgeeiB7Z313.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000284981.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000232190.
HOVERGENiHBG000051.

Family and domain databases

Gene3Di4.10.230.10. 1 hit.
InterProiIPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR024329. Amyloid_glyco_E2_domain.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
[Graphical view]
PANTHERiPTHR23103:SF7. PTHR23103:SF7. 1 hit.
PfamiPF10515. APP_amyloid. 1 hit.
PF12925. APP_E2. 1 hit.
PF03494. Beta-APP. 1 hit.
[Graphical view]
PRINTSiPR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
SUPFAMiSSF109843. SSF109843. 1 hit.
PROSITEiPS00320. A4_INTRA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z313-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLKKYVRAEQ KDRQHTLKHF EHVRMVDPKK AAQIRSQVMT HLRVIYERMN
60 70 80 90 100
QSLSLLYNVP AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA
110 120 130 140 150
LMPSLTETKT TVELLPVNGE FSLDDLQPWH SFGADSVPAN TENEVEPVDA
160 170 180 190 200
RPAADRGLTT RPGSGLTNIK TEEISEVKMD AEFRHDSGYE VHHQKLVFFA
210 220 230 240 250
EDVGSNKGAI IGLMVGGVVI ATVIVITLVM LKKKQYTSIH HGVVEVDAAV
260 270
TPEERHLSKM QQNGYENPTY KFFEQMQN
Length:278
Mass (Da):31,450
Last modified:March 3, 2009 - v1
Checksum:i0E42419A05F5387E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295373 mRNA. Translation: BAH12049.1.
UniGeneiHs.434980.

Genome annotation databases

UCSCiuc011acg.2. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295373 mRNA. Translation: BAH12049.1.
UniGeneiHs.434980.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000284981.

Chemistry

BindingDBiB7Z313.

Proteomic databases

PRIDEiB7Z313.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

UCSCiuc011acg.2. human.

Phylogenomic databases

HOGENOMiHOG000232190.
HOVERGENiHBG000051.

Miscellaneous databases

NextBioi35479126.

Gene expression databases

BgeeiB7Z313.

Family and domain databases

Gene3Di4.10.230.10. 1 hit.
InterProiIPR008155. Amyloid_glyco.
IPR013803. Amyloid_glyco_Abeta.
IPR024329. Amyloid_glyco_E2_domain.
IPR019745. Amyloid_glyco_intracell_CS.
IPR028866. APP.
IPR019543. APP_amyloid_C.
[Graphical view]
PANTHERiPTHR23103:SF7. PTHR23103:SF7. 1 hit.
PfamiPF10515. APP_amyloid. 1 hit.
PF12925. APP_E2. 1 hit.
PF03494. Beta-APP. 1 hit.
[Graphical view]
PRINTSiPR00203. AMYLOIDA4.
PR00204. BETAAMYLOID.
SUPFAMiSSF109843. SSF109843. 1 hit.
PROSITEiPS00320. A4_INTRA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: Corpus callosumImported.

Entry informationi

Entry nameiB7Z313_HUMAN
AccessioniPrimary (citable) accession number: B7Z313
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: June 24, 2015
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.