UniProtKB - B7Z313 (B7Z313_HUMAN)
(max 400 entries)x
Your basket is currently empty. i
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
Protein
Submitted name:
cDNA FLJ50525, highly similar to Amyloid beta A4 protein (APP) (ABPP) (Alzheimer disease amyloid protein homolog)
Gene
N/A
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ50525, highly similar to Amyloid beta A4 protein (APP) (ABPP) (Alzheimer disease amyloid protein homolog)Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 209 – 231 | HelicalSequence analysisAdd BLAST | 23 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 56 | APP_E2InterPro annotationAdd BLAST | 56 | |
Domaini | 183 – 221 | Beta-APPInterPro annotationAdd BLAST | 39 | |
Domaini | 224 – 274 | APP_amyloidInterPro annotationAdd BLAST | 51 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 63 – 83 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisPhylogenomic databases
eggNOGi | KOG3540. Eukaryota. ENOG410ZW2A. LUCA. |
HOGENOMi | HOG000232190. |
HOVERGENi | HBG000051. |
Family and domain databases
Gene3Di | 1.20.120.770. 1 hit. 2.30.29.30. 1 hit. 4.10.230.10. 1 hit. |
InterProi | View protein in InterPro IPR008155. Amyloid_glyco. IPR013803. Amyloid_glyco_Abeta. IPR037071. Amyloid_glyco_Abeta_sf. IPR024329. Amyloid_glyco_E2_domain. IPR019745. Amyloid_glyco_intracell_CS. IPR028866. APP. IPR019543. APP_amyloid_C. IPR036176. E2_sf. IPR011993. PH-like_dom_sf. |
PANTHERi | PTHR23103. PTHR23103. 1 hit. PTHR23103:SF7. PTHR23103:SF7. 1 hit. |
Pfami | View protein in Pfam PF10515. APP_amyloid. 1 hit. PF12925. APP_E2. 1 hit. PF03494. Beta-APP. 1 hit. |
PRINTSi | PR00203. AMYLOIDA4. PR00204. BETAAMYLOID. |
SUPFAMi | SSF109843. SSF109843. 1 hit. |
PROSITEi | View protein in PROSITE PS00320. A4_INTRA. 1 hit. |
i Sequence
Sequence statusi: Complete.
B7Z313-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLKKYVRAEQ KDRQHTLKHF EHVRMVDPKK AAQIRSQVMT HLRVIYERMN
60 70 80 90 100
QSLSLLYNVP AVAEEIQDEV DELLQKEQNY SDDVLANMIS EPRISYGNDA
110 120 130 140 150
LMPSLTETKT TVELLPVNGE FSLDDLQPWH SFGADSVPAN TENEVEPVDA
160 170 180 190 200
RPAADRGLTT RPGSGLTNIK TEEISEVKMD AEFRHDSGYE VHHQKLVFFA
210 220 230 240 250
EDVGSNKGAI IGLMVGGVVI ATVIVITLVM LKKKQYTSIH HGVVEVDAAV
260 270
TPEERHLSKM QQNGYENPTY KFFEQMQN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK295373 mRNA. Translation: BAH12049.1. |
UniGenei | Hs.434980. |
Similar proteinsi
Entry informationi
Entry namei | B7Z313_HUMAN | |
Accessioni | B7Z313Primary (citable) accession number: B7Z313 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | March 3, 2009 |
Last sequence update: | March 3, 2009 | |
Last modified: | March 28, 2018 | |
This is version 58 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |