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Protein
Submitted name:

Ral guanine nucleotide dissociation stimulator-like 1, isoform CRA_d

Gene

RGL1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Ral guanine nucleotide dissociation stimulator-like 1, isoform CRA_dImported
Submitted name:
cDNA FLJ50518, highly similar to Ral guanine nucleotide dissociation stimulator-like 1Imported
Gene namesi
Name:RGL1Imported
ORF Names:hCG_2025089Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 194N-terminal Ras-GEFInterPro annotationAdd BLAST132
Domaini230 – 499Ras-GEFInterPro annotationAdd BLAST270
Domaini646 – 733Ras-associatingInterPro annotationAdd BLAST88

Phylogenomic databases

eggNOGiKOG3629. Eukaryota.
ENOG410ZUT5. LUCA.
HOVERGENiHBG005864.

Family and domain databases

CDDicd00155. RasGEF. 1 hit.
cd06224. REM. 1 hit.
Gene3Di1.10.840.10. 1 hit.
InterProiView protein in InterPro
IPR000159. RA_dom.
IPR000651. Ras-like_Gua-exchang_fac_N.
IPR019804. Ras_G-nucl-exch_fac_CS.
IPR023578. Ras_GEF_dom.
IPR001895. RASGEF_cat_dom.
IPR030748. RGL1.
IPR029071. Ubiquitin-rel_dom.
PANTHERiPTHR23113:SF258. PTHR23113:SF258. 1 hit.
PfamiView protein in Pfam
PF00788. RA. 1 hit.
PF00617. RasGEF. 1 hit.
PF00618. RasGEF_N. 1 hit.
SMARTiView protein in SMART
SM00314. RA. 1 hit.
SM00147. RasGEF. 1 hit.
SM00229. RasGEFN. 1 hit.
SUPFAMiSSF48366. SSF48366. 2 hits.
SSF54236. SSF54236. 1 hit.
PROSITEiView protein in PROSITE
PS50200. RA. 1 hit.
PS00720. RASGEF. 1 hit.
PS50009. RASGEF_CAT. 1 hit.
PS50212. RASGEF_NTER. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z2W5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEVKPVGEPT QEVSKFKLST KVESTGHWLV EDHVRIWEVL KTEEVEGDQL
60 70 80 90 100
PPGHTVSQYE TCKIRTIKAG TLEKLVENLL TAFGDNDFTY ISIFLSTYRG
110 120 130 140 150
FASTKEVLEL LLDRYGNLTS PNCEEDGSQS SSESKMVIRN AIASILRAWL
160 170 180 190 200
DQCAEDFREP PHFPCLQKLL DYLTRMMPGS DPERRAQNLL EQFQKQEVET
210 220 230 240 250
DNGLPNTISF SLEEEEELEG GESAEFTCFS EDLVAEQLTY MDAQLFKKVV
260 270 280 290 300
PHHCLGCIWS RRDKKENKHL APTIRATISQ FNTLTKCVVS TILGGKELKT
310 320 330 340 350
QQRAKIIEKW INIAHECRLL KNFSSLRAIV SALQSNSIYR LKKTWAAVPR
360 370 380 390 400
DRMLMFEELS DIFSDHNNHL TSRELLMKEG TSKFANLDSS VKENQKRTQR
410 420 430 440 450
RLQLQKDMGV MQGTVPYLGT FLTDLTMLDT ALQDYIEGGL INFEKRRREF
460 470 480 490 500
EVIAQIKLLQ SACNSYCMTP DQKFIQWFQR QQLLTEEESY ALSCEIEAAA
510 520 530 540 550
DASTTSPKPR KSMVKRLSLL FLGSDMITSP TPTKEQPKST ASGSSGESMD
560 570 580 590 600
SVSVSSCESN HSEAEEGSIT PMDTPDEPQK KLSESSSSCS SIHSMDTNSS
610 620 630 640 650
GMSSLINPLS SPPSCNNNPK IHKRSVSVTS ITSTVLPPVY NQQNEDTCII
660 670 680 690 700
RISVEDNNGN MYKSIMLTSQ DKTPAVIQRA MLKHNLDSDP AEEYELVQVI
710 720 730 740 750
SEDKELVIPD SANVFYAMNS QVNFDFILRK KNSMEEQVKL RSRTSLTLPR
760
TAKRGCWSNR HSKITL
Length:766
Mass (Da):86,553
Last modified:March 3, 2009 - v1
Checksum:i8A232F33576D7752
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295179 mRNA. Translation: BAH12001.1.
CH471067 Genomic DNA. Translation: EAW91168.1.
RefSeqiNP_001284598.1. NM_001297669.1.
NP_001284599.1. NM_001297670.1.
UniGeneiHs.497148.

Genome annotation databases

GeneIDi23179.

Similar proteinsi

Entry informationi

Entry nameiB7Z2W5_HUMAN
AccessioniPrimary (citable) accession number: B7Z2W5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: August 30, 2017
This is version 75 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.