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Protein
Submitted name:

cDNA FLJ52540, highly similar to Lysosome-associated membrane glycoprotein 2

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ52540, highly similar to Lysosome-associated membrane glycoprotein 2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei265 – 288HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

LysosomePROSITE-ProRule annotation, Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi42 ↔ 78PROSITE-ProRule annotation
Disulfide bondi220 ↔ 257PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotation

Proteomic databases

MaxQBiB7Z2R9.
PaxDbiB7Z2R9.
PeptideAtlasiB7Z2R9.
PRIDEiB7Z2R9.

Structurei

3D structure databases

ProteinModelPortaliB7Z2R9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the LAMP family.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG4818. Eukaryota.
ENOG410XQ96. LUCA.
HOVERGENiHBG052303.

Family and domain databases

InterProiView protein in InterPro
IPR002000. Lysosome-assoc_membr_glycop.
PANTHERiPTHR11506. PTHR11506. 1 hit.
PfamiView protein in Pfam
PF01299. Lamp. 1 hit.
PRINTSiPR00336. LYSASSOCTDMP.
PROSITEiView protein in PROSITE
PS51407. LAMP_3. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z2R9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCFRLFPVP GSGLVLVCLV LGILTVDELL AIRIPLNDLF RCNSLSTLEK
60 70 80 90 100
NDVVQHYWDV LVQAFVQNGT VSTNEFLCDK DKTSTVAPTI HTTVPSPTTT
110 120 130 140 150
PTPKEKPEAG TYSVNNGNDT CLLATMGLQL NITQDKVASV ININPNTTHS
160 170 180 190 200
TGSCRSHTAL LRLNSSTIKY LDFVFAVKNE NRFYLKEVNI SMYLVNGSVF
210 220 230 240 250
SIANNNLSYW DAPLGSSYMC NKEQTVSVSG AFQINTFDLR VQPFNVTQGK
260 270 280 290 300
YSTAEECSAD SDLNFLIPVA VGVALGFLII VVFISYMIGR RKSRTGYQSV
Length:300
Mass (Da):32,980
Last modified:March 3, 2009 - v1
Checksum:i22FD69D9C72EE378
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK295038 mRNA. Translation: BAH11955.1.
UniGeneiHs.496684.

Similar proteinsi

Entry informationi

Entry nameiB7Z2R9_HUMAN
AccessioniPrimary (citable) accession number: B7Z2R9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: August 30, 2017
This is version 56 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation