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Protein
Submitted name:

14-3-3 protein zeta/delta

Gene

YWHAZ

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
14-3-3 protein zeta/deltaImported
Submitted name:
cDNA FLJ50142, highly similar to 14-3-3 protein zeta/delta (Protein kinase Cinhibitor protein 1)Imported
Gene namesi
Name:YWHAZImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 8

Organism-specific databases

EuPathDBiHostDB:ENSG00000164924.17.
HGNCiHGNC:12855. YWHAZ.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000164924.

PTM / Processingi

Proteomic databases

MaxQBiB7Z2E6.

Expressioni

Gene expression databases

BgeeiENSG00000164924.
ExpressionAtlasiB7Z2E6. baseline and differential.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 12214_3_3InterPro annotationAdd BLAST122

Sequence similaritiesi

Belongs to the 14-3-3 family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0841. Eukaryota.
COG5040. LUCA.
GeneTreeiENSGT00760000119116.
HOGENOMiHOG000240379.
HOVERGENiHBG050423.

Family and domain databases

Gene3Di1.20.190.20. 1 hit.
InterProiView protein in InterPro
IPR000308. 14-3-3.
IPR023409. 14-3-3_CS.
IPR036815. 14-3-3_dom_sf.
IPR023410. 14-3-3_domain.
PANTHERiPTHR18860. PTHR18860. 1 hit.
PfamiView protein in Pfam
PF00244. 14-3-3. 1 hit.
PRINTSiPR00305. 1433ZETA.
SMARTiView protein in SMART
SM00101. 14_3_3. 1 hit.
SUPFAMiSSF48445. SSF48445. 1 hit.
PROSITEiView protein in PROSITE
PS00797. 1433_2. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z2E6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKGDYYRYLA EVAAGDDKKG IVDQSQQAYQ EAFEISKKEM QPTHPIRLGL
60 70 80 90 100
ALNFSVFYYE ILNSPEKACS LAKTAFDEAI AELDTLSEES YKDSTLIMQL
110 120
LRDNLTLWTS DTQGDEAEAG EGGEN
Length:125
Mass (Da):13,985
Last modified:March 3, 2009 - v1
Checksum:iE245092E4C7BEEA5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC018781 Genomic DNA. No translation available.
AC027373 Genomic DNA. No translation available.
AK294647 mRNA. Translation: BAH11832.1.
UniGeneiHs.492407.

Genome annotation databases

EnsembliENST00000521309; ENSP00000429623; ENSG00000164924.
ENST00000522819; ENSP00000428775; ENSG00000164924.
UCSCiuc011lhg.2. human.

Similar proteinsi

Entry informationi

Entry nameiB7Z2E6_HUMAN
AccessioniPrimary (citable) accession number: B7Z2E6
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 25, 2017
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported