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B7Z2C7

- B7Z2C7_HUMAN

UniProt

B7Z2C7 - B7Z2C7_HUMAN

Protein
Submitted name:

cDNA FLJ55968, highly similar to Adenylate cyclase type 5 (EC 4.6.1.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 40 (01 Oct 2014)
      Sequence version 1 (03 Mar 2009)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. adenylate cyclase activity Source: Ensembl
    2. nucleotide binding Source: UniProtKB-KW

    GO - Biological processi

    1. adenosine receptor signaling pathway Source: Ensembl
    2. adenylate cyclase-activating dopamine receptor signaling pathway Source: Ensembl
    3. adenylate cyclase-inhibiting dopamine receptor signaling pathway Source: Ensembl
    4. intracellular signal transduction Source: InterPro
    5. locomotory behavior Source: Ensembl
    6. neuromuscular process controlling balance Source: Ensembl

    Keywords - Molecular functioni

    LyaseUniRule annotationSAAS annotation

    Keywords - Ligandi

    Nucleotide-bindingSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    cDNA FLJ55968, highly similar to Adenylate cyclase type 5 (EC 4.6.1.1)Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: Ensembl
    3. primary cilium Source: Ensembl

    Keywords - Cellular componenti

    Membrane

    Expressioni

    Gene expression databases

    ArrayExpressiB7Z2C7.
    BgeeiB7Z2C7.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    HOVERGENiHBG050458.
    KOiK08045.

    Family and domain databases

    Gene3Di3.30.70.1230. 2 hits.
    InterProiIPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    IPR009398. Adenylate_cyclase-like.
    [Graphical view]
    PfamiPF06327. DUF1053. 1 hit.
    PF00211. Guanylate_cyc. 2 hits.
    [Graphical view]
    SMARTiSM00044. CYCc. 2 hits.
    [Graphical view]
    SUPFAMiSSF55073. SSF55073. 2 hits.
    PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    B7Z2C7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAVLCNRAAF HQDHMGLACY ALIAVVLAVQ VVGLLLPQPR SASEGIWWTV    50
    FFIYTIYTLL PVRMRAAVLS GVLLSALHLA IALRTNAQDQ FLLKQLVSNV 100
    LIFSCTNIVG VCTHYPAEVS QRQAFQETRE CIQARLHSQR ENQQQERLLL 150
    SVLPRHVAME MKADINAKQE DMMFHKIYIQ KHDNVSILFA DIEGFTSLAS 200
    QCTAQELVMT LNELFARFDK LAAENHCLRI KILGDCYYCV SGLPEARADH 250
    AHCCVEMGMD MIEAISLVRE VTGVNVNMRV GIHSGRVHCG VLGLRKWQFD 300
    VWSNDVTLAN HMEAGGKAGR IHITKATLNY LNGDYEVEPG CGGERNAYLK 350
    EHSIETFLIL RCTQKRKEEK AMIAKMNRQR TNSIGHNPPH WGAERPFYNH 400
    LGGNQVSKEM KRMGFEDPKD KNAQESANPE DEVDEFLGRA IDARSIDRLR 450
    SEHVRKFLLT FREPDLEKKY SKQVDDRFGA YVACASLVFL FICFVQITIV 500
    PHSIFMLSFY LTCSLLLTLV VFVSVIYSCV KLFPSPLQTL SRKIVRSKMN 550
    STLVGVFTIT LVFLAAFVNM FTCNSRDLLG CLAQEHNISA SQVNACHVAE 600
    SAVNYSLGDE QGFCGSPWPN CNFPEYFTYS VLLSLLACSV FLQISCIGKL 650
    VLMLAIELIY VLIVEVPGVT LFDNADLLVT ANAIDFFNNG TSQCPEHATK 700
    VALKVVTPII ISVFVLALYL HAQQVESTAR LDFLWKLQAT EEKEEMEELQ 750
    AYNRRLLHNI LPKDVAAHFL ARERRNDELY YQSCECVAVM FASIANFSEF 800
    YVELEANNEG VECLRLLNEI IADFDEIISE DRFRQLEKIK TIGSTYMAAS 850
    GLNDSTYDKV GKTHIKALAD FAMKLMDQMK YINEHSFNNF QMKIGLNIGP 900
    VVAGVIGARK PQYDIWGNTV NVASRMDSTG VPDRIQVTTD MYQVLAANTY 950
    QLECRGVVKV KGKGEMMTYF LNGGPPLS 978
    Length:978
    Mass (Da):110,064
    Last modified:March 3, 2009 - v1
    Checksum:i1FF7FB611BD419A8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK294565 mRNA. Translation: BAH11813.1.
    RefSeqiNP_899200.1. NM_183357.2.
    UniGeneiHs.593292.

    Genome annotation databases

    GeneIDi111.
    KEGGihsa:111.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK294565 mRNA. Translation: BAH11813.1 .
    RefSeqi NP_899200.1. NM_183357.2.
    UniGenei Hs.593292.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    DNASUi 111.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 111.
    KEGGi hsa:111.

    Organism-specific databases

    CTDi 111.

    Phylogenomic databases

    HOVERGENi HBG050458.
    KOi K08045.

    Miscellaneous databases

    GenomeRNAii 111.
    NextBioi 427.

    Gene expression databases

    ArrayExpressi B7Z2C7.
    Bgeei B7Z2C7.

    Family and domain databases

    Gene3Di 3.30.70.1230. 2 hits.
    InterProi IPR001054. A/G_cyclase.
    IPR018297. A/G_cyclase_CS.
    IPR009398. Adenylate_cyclase-like.
    [Graphical view ]
    Pfami PF06327. DUF1053. 1 hit.
    PF00211. Guanylate_cyc. 2 hits.
    [Graphical view ]
    SMARTi SM00044. CYCc. 2 hits.
    [Graphical view ]
    SUPFAMi SSF55073. SSF55073. 2 hits.
    PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
    PS50125. GUANYLATE_CYCLASE_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "NEDO human cDNA sequencing project focused on splicing variants."
      Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
      , Sugano S., Nomura N., Isogai T.
      Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: AmygdalaImported.

    Entry informationi

    Entry nameiB7Z2C7_HUMAN
    AccessioniPrimary (citable) accession number: B7Z2C7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: March 3, 2009
    Last sequence update: March 3, 2009
    Last modified: October 1, 2014
    This is version 40 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.