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B7Z2C7

- B7Z2C7_HUMAN

UniProt

B7Z2C7 - B7Z2C7_HUMAN

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Protein
Submitted name:

cDNA FLJ55968, highly similar to Adenylate cyclase type 5 (EC 4.6.1.1)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. adenylate cyclase activity Source: Ensembl
  2. nucleotide binding Source: UniProtKB-KW

GO - Biological processi

  1. adenosine receptor signaling pathway Source: Ensembl
  2. adenylate cyclase-activating dopamine receptor signaling pathway Source: Ensembl
  3. adenylate cyclase-inhibiting dopamine receptor signaling pathway Source: Ensembl
  4. intracellular signal transduction Source: InterPro
  5. locomotory behavior Source: Ensembl
  6. neuromuscular process controlling balance Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotationSAAS annotation

Keywords - Ligandi

Nucleotide-bindingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ55968, highly similar to Adenylate cyclase type 5 (EC 4.6.1.1)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: Ensembl
  3. primary cilium Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiB7Z2C7.
ExpressionAtlasiB7Z2C7. baseline and differential.

Family & Domainsi

Sequence similaritiesi

Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG050458.
KOiK08045.

Family and domain databases

Gene3Di3.30.70.1230. 2 hits.
InterProiIPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR009398. Adenylate_cyclase-like.
IPR029787. Nucleotide_cyclase.
[Graphical view]
PfamiPF06327. DUF1053. 1 hit.
PF00211. Guanylate_cyc. 2 hits.
[Graphical view]
SMARTiSM00044. CYCc. 2 hits.
[Graphical view]
SUPFAMiSSF55073. SSF55073. 2 hits.
PROSITEiPS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

B7Z2C7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVLCNRAAF HQDHMGLACY ALIAVVLAVQ VVGLLLPQPR SASEGIWWTV
60 70 80 90 100
FFIYTIYTLL PVRMRAAVLS GVLLSALHLA IALRTNAQDQ FLLKQLVSNV
110 120 130 140 150
LIFSCTNIVG VCTHYPAEVS QRQAFQETRE CIQARLHSQR ENQQQERLLL
160 170 180 190 200
SVLPRHVAME MKADINAKQE DMMFHKIYIQ KHDNVSILFA DIEGFTSLAS
210 220 230 240 250
QCTAQELVMT LNELFARFDK LAAENHCLRI KILGDCYYCV SGLPEARADH
260 270 280 290 300
AHCCVEMGMD MIEAISLVRE VTGVNVNMRV GIHSGRVHCG VLGLRKWQFD
310 320 330 340 350
VWSNDVTLAN HMEAGGKAGR IHITKATLNY LNGDYEVEPG CGGERNAYLK
360 370 380 390 400
EHSIETFLIL RCTQKRKEEK AMIAKMNRQR TNSIGHNPPH WGAERPFYNH
410 420 430 440 450
LGGNQVSKEM KRMGFEDPKD KNAQESANPE DEVDEFLGRA IDARSIDRLR
460 470 480 490 500
SEHVRKFLLT FREPDLEKKY SKQVDDRFGA YVACASLVFL FICFVQITIV
510 520 530 540 550
PHSIFMLSFY LTCSLLLTLV VFVSVIYSCV KLFPSPLQTL SRKIVRSKMN
560 570 580 590 600
STLVGVFTIT LVFLAAFVNM FTCNSRDLLG CLAQEHNISA SQVNACHVAE
610 620 630 640 650
SAVNYSLGDE QGFCGSPWPN CNFPEYFTYS VLLSLLACSV FLQISCIGKL
660 670 680 690 700
VLMLAIELIY VLIVEVPGVT LFDNADLLVT ANAIDFFNNG TSQCPEHATK
710 720 730 740 750
VALKVVTPII ISVFVLALYL HAQQVESTAR LDFLWKLQAT EEKEEMEELQ
760 770 780 790 800
AYNRRLLHNI LPKDVAAHFL ARERRNDELY YQSCECVAVM FASIANFSEF
810 820 830 840 850
YVELEANNEG VECLRLLNEI IADFDEIISE DRFRQLEKIK TIGSTYMAAS
860 870 880 890 900
GLNDSTYDKV GKTHIKALAD FAMKLMDQMK YINEHSFNNF QMKIGLNIGP
910 920 930 940 950
VVAGVIGARK PQYDIWGNTV NVASRMDSTG VPDRIQVTTD MYQVLAANTY
960 970
QLECRGVVKV KGKGEMMTYF LNGGPPLS
Length:978
Mass (Da):110,064
Last modified:March 3, 2009 - v1
Checksum:i1FF7FB611BD419A8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK294565 mRNA. Translation: BAH11813.1.
RefSeqiNP_899200.1. NM_183357.2.
UniGeneiHs.593292.

Genome annotation databases

GeneIDi111.
KEGGihsa:111.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK294565 mRNA. Translation: BAH11813.1 .
RefSeqi NP_899200.1. NM_183357.2.
UniGenei Hs.593292.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

DNASUi 111.
Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 111.
KEGGi hsa:111.

Organism-specific databases

CTDi 111.

Phylogenomic databases

HOVERGENi HBG050458.
KOi K08045.

Miscellaneous databases

GenomeRNAii 111.
NextBioi 427.

Gene expression databases

Bgeei B7Z2C7.
ExpressionAtlasi B7Z2C7. baseline and differential.

Family and domain databases

Gene3Di 3.30.70.1230. 2 hits.
InterProi IPR001054. A/G_cyclase.
IPR018297. A/G_cyclase_CS.
IPR009398. Adenylate_cyclase-like.
IPR029787. Nucleotide_cyclase.
[Graphical view ]
Pfami PF06327. DUF1053. 1 hit.
PF00211. Guanylate_cyc. 2 hits.
[Graphical view ]
SMARTi SM00044. CYCc. 2 hits.
[Graphical view ]
SUPFAMi SSF55073. SSF55073. 2 hits.
PROSITEi PS00452. GUANYLATE_CYCLASE_1. 2 hits.
PS50125. GUANYLATE_CYCLASE_2. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "NEDO human cDNA sequencing project focused on splicing variants."
    Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T.
    , Sugano S., Nomura N., Isogai T.
    Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: AmygdalaImported.

Entry informationi

Entry nameiB7Z2C7_HUMAN
AccessioniPrimary (citable) accession number: B7Z2C7
Entry historyi
Integrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: October 29, 2014
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.