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Protein
Submitted name:

cDNA FLJ51566, highly similar to Pyruvate dehydrogenase (lipoamide) kinase isozyme 1 (EC 2.7.11.2)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, Transferase
LigandPyruvateImported

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ51566, highly similar to Pyruvate dehydrogenase (lipoamide) kinase isozyme 1 (EC 2.7.11.2)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

MaxQBiB7Z207.
PaxDbiB7Z207.
PeptideAtlasiB7Z207.
PRIDEiB7Z207.

Expressioni

Gene expression databases

BgeeiENSG00000152256.

Structurei

3D structure databases

ProteinModelPortaliB7Z207.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 238Histidine kinaseInterPro annotationAdd BLAST124

Phylogenomic databases

eggNOGiKOG0787. Eukaryota.
COG0642. LUCA.
HOVERGENiHBG000511.

Family and domain databases

Gene3Di1.20.140.20. 1 hit.
3.30.565.10. 1 hit.
InterProiView protein in InterPro
IPR018955. BCDHK/PDK_N.
IPR003594. HATPase_C.
IPR005467. His_kinase_dom.
PfamiView protein in Pfam
PF10436. BCDHK_Adom3. 1 hit.
PF02518. HATPase_c. 1 hit.
SMARTiView protein in SMART
SM00387. HATPase_c. 1 hit.
SUPFAMiSSF55874. SSF55874. 1 hit.
SSF69012. SSF69012. 1 hit.
PROSITEiView protein in PROSITE
PS50109. HIS_KIN. 1 hit.

Sequencei

Sequence statusi: Complete.

B7Z207-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQGVIEYKE SFGVDPVTSQ NVQYFLDRFY MSRISIRMLL NQHSLLFGGK
60 70 80 90 100
GKGSPSHRKH IGSINPNCNV LEVIKDGYEN ARRLCDLYYI NSPELELEEL
110 120 130 140 150
NAKSPGQPIQ VVYVPSHLYH MVFELFKNAM RATMEHHANR GVYPPIQVHV
160 170 180 190 200
TLGNEDLTVK MSDRGGGVPL RKIDRLFNYM YSTAPRPRVE TSRAVPLAGF
210 220 230 240 250
GYGLPISRLY AQYFQGDLKL YSLEGYGTDA VIYIKALSTD SIERLPVYNK
260 270 280
AAWKHYNTNH EADDWCVPSR EPKDMTTFRS A
Length:281
Mass (Da):32,036
Last modified:March 3, 2009 - v1
Checksum:iD6AABC3D0CFA611F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK294194 mRNA. Translation: BAH11693.1.
UniGeneiHs.470633.
Hs.733780.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiB7Z207_HUMAN
AccessioniPrimary (citable) accession number: B7Z207
Entry historyiIntegrated into UniProtKB/TrEMBL: March 3, 2009
Last sequence update: March 3, 2009
Last modified: July 5, 2017
This is version 58 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.