B7Z1W1 (B7Z1W1_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Glutamate receptor 1 Ensembl ENSP00000441507

Submitted name:
cDNA FLJ52587, highly similar to Glutamate receptor 1 EMBL BAH11647.1

Gene names

Name:

GRIA1 Ensembl ENSP00000441507

Organism

Homo sapiens (Human) [Reference proteome] EMBL BAH11647.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	716 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Biological process	Ion transport Transport
Cellular component	Cell junction Cell membrane SAAS SAAS019594 Membrane Postsynaptic cell membrane SAAS SAAS019594 Synapse
Domain	Transmembrane Transmembrane helix SAAS SAAS019594
Molecular function	Ion channel Ligand-gated ion channel SAAS SAAS019594 Receptor SAAS SAAS019594 EMBL BAH11647.1
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	ionotropic glutamate receptor signaling pathway Inferred from electronic annotation. Source: GOC
Cellular_component	cell junction Inferred from electronic annotation. Source: UniProtKB-KW integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-KW postsynaptic membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	extracellular-glutamate-gated ion channel activity Inferred from electronic annotation. Source: InterPro ionotropic glutamate receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	B7Z1W1 [UniParc]. Last modified March 3, 2009. Version 1. Checksum: 74E47E920EF71AC0	FASTA	716	81,131
	10 20 30 40 50 60 MQHIFAFFCT GFLGAVVGAN FPNNIQIVCS QFSKGVYAIF GFYERRTVNM LTSFCGALHV 70 80 90 100 110 120 CFITPSFPVD TSNQFVLQLR PELQDALISI IDHYKWQKFV YIYDADRGLS VLQKVLDTAA 130 140 150 160 170 180 EKNWQVTAVN ILTTTEEGYR MLFQDLEKKK ERLVVVDCES ERLNAILGQI IKLEKNGIGY 190 200 210 220 230 240 HYILANLGFM DIDLNKFKES GANVTGFQLV NYTDTIPAKI MQQWKNSDAR DHTRVDWKRP 250 260 270 280 290 300 KYTSALTYDG VKVMAEAFQS LRRQRIDISR RGNAGDCLAN PAVPWGQGID IQRALQQVRF 310 320 330 340 350 360 EGLTGNVQFN EKGRRTNYTL HVIEMKHDGI RKIGYWNEDD KFVPAATDAQ AGGDNSSVQN 370 380 390 400 410 420 RTYIVTTILE DPYVMLKKNA NQFEGNDRYE GYCVELAAEI AKHVGYSYRL EIVSDGKYGA 430 440 450 460 470 480 RDPDTKAWNG MVGELVYGRA DVAVAPLTIT LVREEVIDFS KPFMSLGISI MIKKPQKSKP 490 500 510 520 530 540 GVFSFLDPLA YEIWMCIVFA YIGVSVVLFL VSRFSPYEWH SEEFEEGRDQ TTSDQSNEFG 550 560 570 580 590 600 IFNSLWFSLG AFMQQGCDIS PRSLSGRIVG GVWWFFTLII ISSYTANLAA FLTVERMVSP 610 620 630 640 650 660 IESAEDLAKQ TEIAYGTLEA GSTKEFFRRS KIAVFEKMWT YMKSAEPSVF VRTTEEGMIR 670 680 690 700 710 VRKSKGKYAY LLESTMNEYI EQRKPCDTMK VGGNLDSKGY GIATPKGSAL RTRQAL

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The DNA sequence and comparative analysis of human chromosome 5." Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S. , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M. Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[2]	"NEDO human cDNA sequencing project focused on splicing variants." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAH11647.1.
[3]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC010613 Genomic DNA. No translation available. AC025156 Genomic DNA. No translation available. AC091960 Genomic DNA. No translation available. AC091962 Genomic DNA. No translation available. AK294011 mRNA. Translation: BAH11647.1.
IPI	IPI00956375.
UniGene	Hs.519693. Hs.737709.
3D structure databases
SMR	B7Z1W1. Positions 29-712.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000537037; ENSP00000441507; ENSG00000155511.
Organism-specific databases
HGNC	HGNC:4571. GRIA1.
GenAtlas	Search...
Phylogenomic databases
HOVERGEN	HBG051839.
Gene expression databases
ArrayExpress	B7Z1W1.
Family and domain databases
InterPro	IPR001828. ANF_lig-bd_rcpt. IPR019594. Glu_rcpt_Glu/Gly-bd. IPR001320. Iontro_glu_rcpt. IPR001508. NMDA_rcpt. [Graphical view]
Pfam	PF01094. ANF_receptor. 1 hit. PF00060. Lig_chan. 1 hit. PF10613. Lig_chan-Glu_bd. 1 hit. [Graphical view]
PRINTS	PR00177. NMDARECEPTOR.
SMART	SM00918. Lig_chan-Glu_bd. 1 hit. SM00079. PBPe. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	35478836.

Entry information

Entry name

B7Z1W1_HUMAN

Accession

Primary (citable) accession number: B7Z1W1

Entry history

Integrated into UniProtKB/TrEMBL:	March 3, 2009
Last sequence update:	March 3, 2009
Last modified:	May 1, 2013
This is version 32 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.